{"id":58015,"date":"2024-02-27T18:12:30","date_gmt":"2024-02-27T18:12:30","guid":{"rendered":"https:\/\/medsname.com\/etibo\/"},"modified":"2026-04-30T10:17:00","modified_gmt":"2026-04-30T10:17:00","slug":"etibo","status":"publish","type":"product","link":"https:\/\/medsbase.com\/sv\/product\/etibo\/","title":{"rendered":"Etibo"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 8px 0;\"><strong>\ud83d\udca1 Snabbt svar<\/strong><\/p>\n<p style=\"margin:0;\"><strong>Etibo<\/strong> \u00e4r <strong>lapatinib 250 mg<\/strong>, en <strong>dual HER2\/EGFR tyrosine kinase inhibitor<\/strong> for advanced or metastatic <strong>HER2-positive breast cancer<\/strong>. Oral once-daily therapy combined with capecitabine or other regimens, usually after trastuzumab (Herceptin) failure. Significant side effects include diarrhoea, rash, and cardiotoxicity; requires close oncologist supervision and ECG monitoring.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Vad du f\u00e5r med MedsBase:<\/strong> WHO-GMP-certifierad tillverkare \u00b7 Diskret f\u00f6rpackning \u00b7 V\u00e4rldsvid leverans \u00b7 1 400+ verifierade <a href=\"https:\/\/medsbase.com\/sv\/reviews\/\">kundrecensioner<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Varje best\u00e4llning omfattas av v\u00e5r <a href=\"https:\/\/medsbase.com\/sv\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 om din f\u00f6rs\u00e4ndelse inte anl\u00e4nder inom 20 arbetsdagar, skickar vi om den.<\/p>\n<h3>Varf\u00f6r best\u00e4lla fr\u00e5n MedsBase<\/h3>\n<p>V\u00e5ra generiska l\u00e4kemedel kommer fr\u00e5n WHO-GMP-certifierade tillverkare och skickas v\u00e4rldsvidt i diskreta, enkla f\u00f6rpackningar \u2014 inget l\u00e4kemedelsnamn p\u00e5 f\u00f6rs\u00e4ndelsens utsida. Kortbetalningar hanteras via en reglerad betalningsprocessor (kontoutdrag visar en reglerad kortbetalningsprocessor \u2014 aldrig \u201cMedsBase\u201d eller n\u00e5got l\u00e4kemedelsnamn). Krypto och SEPA-bank\u00f6verf\u00f6ring accepteras ocks\u00e5. Varje best\u00e4llning backas upp av v\u00e5r Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.95em;\">\n<strong>\ud83d\udd12 Varf\u00f6r best\u00e4lla fr\u00e5n MedsBase:<\/strong> Verifierad \u00e4kta tillverkare \u00b7 V\u00e4rldsvid leverans \u00b7 S\u00e4ker kassaprocess (kreditkort, krypto) \u00b7 Betyg 4.9\u2605 av 1 400+ kunder\n<\/div>\n<h2><strong>What Is Etibo?<\/strong><\/h2>\n<p>Etibo is a branded generic of <strong>lapatinib<\/strong> 250 mg, a small-molecule tyrosine kinase inhibitor that targets <strong>HER2 (ErbB2)<\/strong> och <strong>EGFR (ErbB1)<\/strong>. Lapatinib blocks intracellular signaling downstream of these receptors, halting proliferation of HER2-positive cancer cells. Manufactured by Natco Pharma.<\/p>\n<p><strong>Kritiskt:<\/strong> Lapatinib is an oncology drug used only under specialist supervision. It is not a general women&#8217;s health product. Use strictly according to oncologist protocol \u2014 typically after trastuzumab resistance develops.<\/p>\n<h2><strong>Kliniska anv\u00e4ndningsomr\u00e5den<\/strong><\/h2>\n<ul>\n<li><strong>Advanced\/metastatic HER2+ breast cancer<\/strong>: 1250 mg daily (5 tablets) + capecitabine \u2014 after trastuzumab failure.<\/li>\n<li><strong>HER2+ breast cancer with letrozole<\/strong> in postmenopausal women with ER+\/HER2+ metastatic disease.<\/li>\n<li><strong>Not indicated<\/strong> for adjuvant (early-stage curative) therapy \u2014 trastuzumab \u00b1 pertuzumab remain standard there.<\/li>\n<\/ul>\n<h2><strong>Hur man tar<\/strong><\/h2>\n<ol>\n<li>Ta <strong>1250 mg (5 tablets) once daily<\/strong>, <strong>at least 1 hour before or after food<\/strong>. Food significantly increases absorption and shifts dosing parameters; consistency matters.<\/li>\n<li>Typical partner drug: capecitabine 2000 mg\/m\u00b2\/day on days 1\u201314 of a 21-day cycle.<\/li>\n<li>ECG and LVEF monitoring at baseline and every 3 months (cardiotoxicity risk).<\/li>\n<li>Manage diarrhoea proactively \u2014 often grade 1\u20133, common in first cycle. Loperamide, hydration, dose reduction as needed.<\/li>\n<li>Avoid grapefruit, Seville oranges, and CYP3A4 inhibitors\/inducers.<\/li>\n<\/ol>\n<h2><strong>Biverkningar<\/strong><\/h2>\n<p><strong>Mycket vanligt:<\/strong> diarrhoea (60\u201380%), rash (40\u201360%), nausea, vomiting, fatigue, hand-foot syndrome, palmar-plantar erythrodysesthesia (with capecitabine combo).<\/p>\n<p><strong>Betydande:<\/strong> <strong>hepatotoxicity<\/strong> (monitor LFTs), <strong>cardiotoxicity \/ reduced LVEF<\/strong> (5\u20136%), QT prolongation, interstitial lung disease (rare but serious).<\/p>\n<p><strong>Allvarligt:<\/strong> severe liver injury, heart failure, severe skin reactions (Stevens-Johnson), pulmonary toxicity.<\/p>\n<h2><strong>Who Should Not Take Etibo<\/strong><\/h2>\n<ul>\n<li>HER2-negative breast cancer (ineffective)<\/li>\n<li>Sv\u00e5r leversvikt<\/li>\n<li>Symptomatic heart failure or severe cardiac dysfunction<\/li>\n<li>Pregnancy \u2014 teratogenic<\/li>\n<li>Concurrent strong CYP3A4 inhibitors or inducers without dose adjustment<\/li>\n<\/ul>\n<h2><strong>L\u00e4kemedelsinteraktioner<\/strong><\/h2>\n<ul>\n<li><strong>Starka CYP3A4-h\u00e4mmare<\/strong> (ketoconazole, ritonavir, clarithromycin, grapefruit): raise lapatinib levels significantly.<\/li>\n<li><strong>Starka CYP3A4-inducerare<\/strong> (rifampicin, carbamazepine, phenytoin, St John&#8217;s Wort): reduce lapatinib levels and efficacy.<\/li>\n<li><strong>PPIs, H2 blockers<\/strong>: reduce absorption \u2014 avoid or space by hours.<\/li>\n<li><strong>Warfarin, digoxin<\/strong>: may increase levels.<\/li>\n<\/ul>\n<h2><strong>F\u00f6rvaring<\/strong><\/h2>\n<p>Store at room temperature (15\u201330 \u00b0C), away from moisture. Keep in original packaging. Keep out of reach of children.<\/p>\n<h2 id=\"faqs\">Vanliga fr\u00e5gor<\/h2>\n<h3 class=\"wp-block-heading\">When is lapatinib used?<\/h3>\n<p>Advanced\/metastatic HER2-positive breast cancer, typically after trastuzumab (Herceptin) resistance. Not used for early-stage curative therapy.<\/p>\n<h3 class=\"wp-block-heading\">Why take on empty stomach?<\/h3>\n<p>Food increases lapatinib absorption 4\u20135\u00d7, making dosing unpredictable. Standard is consistent fasting \u2014 1 hour before or after food \u2014 at a fixed time each day.<\/p>\n<h3 class=\"wp-block-heading\">How bad is the diarrhoea?<\/h3>\n<p>Common, often grade 1\u20132; manageable with loperamide and hydration. Grade 3+ diarrhoea may require treatment interruption and dose reduction. Report early.<\/p>\n<h3 class=\"wp-block-heading\">Will lapatinib damage my heart?<\/h3>\n<p>About 5\u20136% of patients have asymptomatic LVEF drops. ECG + echocardiogram at baseline and every 3 months. Usually reversible on dose adjustment or interruption.<\/p>\n<h3 class=\"wp-block-heading\">Can I take lapatinib with trastuzumab?<\/h3>\n<p>Combination lapatinib + trastuzumab is used in specific protocols. Not routine without oncologist supervision.<\/p>\n<h3 class=\"wp-block-heading\">What about fertility?<\/h3>\n<p>Effective contraception required during treatment and for 1 week after (teratogenic). Men should use effective contraception during and 3 months after.<\/p>\n<h3 class=\"wp-block-heading\">Why is this in the Women&#039;s Health category?<\/h3>\n<p>HER2+ breast cancer disproportionately affects women (though rarely men get HER2+ breast cancer). Categorisation reflects the population, not a strict clinical cluster.<\/p>\n<h3 class=\"wp-block-heading\">Is lapatinib still first-line?<\/h3>\n<p>For second-line HER2+ metastatic disease (after trastuzumab), lapatinib + capecitabine was standard for years. Newer options (T-DM1\/Kadcyla, T-DXd\/Enhertu, tucatinib) have since largely supplanted it in first-world oncology \u2014 lapatinib remains important where newer agents are unavailable.<\/p>\n<h3 class=\"wp-block-heading\">Relaterade produkter f\u00f6r kvinnors h\u00e4lsa<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/sv\/tamodex\/\">Tamodex (Tamoxifen 10 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/tamilong\/\">Tamilong (Tamoxifen 20 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/letroheal\/\">Letroheal (Letrozole 2.5 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/duphaston\/\">Duphaston (Dydrogesteron 10 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/deviry\/\">Deviry (Medroxyprogesteron 10 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/naprosyn\/\">Naprosyn (Naproxen 250 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/candid-v-gel\/\">Candid-V Gel (Clotrimazole)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.9em;\">\n<p style=\"margin:0;\"><strong>\u2695\ufe0f Medicinsk ansvarsfriskrivning:<\/strong> Informationen \u00e4r av pedagogisk karakt\u00e4r och ers\u00e4tter inte medicinsk r\u00e5dgivning. Konsultera en l\u00e4kare innan du p\u00e5b\u00f6rjar, avslutar eller \u00e4ndrar n\u00e5gon medicinering, s\u00e4rskilt vid cancerbehandling, hormonella behandlingar och receptbelagda produkter.<\/p>\n<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Relaterade alternativ<\/h3>\n<p>Andra onkologiska l\u00e4kemedel som finns i lager tillsammans med denna produkt:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/sv\/verpin\/\">Verpin<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/triohale-rotacaps\/\">Triohale Rotacaps<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/inderal\/\">Inderal<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/hydrocl\/\">Hydrocl<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/sv\/ezedoc\/\">Ezedoc<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Targets cancer cells<br \/>\n\u2705 Inhibits tumor growth<br \/>\n\u2705 Treats breast cancer<br \/>\n\u2705 Blocks HER2 receptors<br \/>\n\u2705 F\u00f6rb\u00e4ttrar \u00f6verlevnadsgraden<\/p>\n<p>Etibo contains Lapatinib.<\/p>","protected":false},"featured_media":58016,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3595,3141,3223,3502],"product_tag":[4402,4403],"class_list":{"0":"post-58015","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-cancer-medication","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_cat-womens-health","10":"product_tag-etibo","11":"product_tag-lapatinib","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product\/58015","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/comments?post=58015"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/media\/58016"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/media?parent=58015"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product_brand?post=58015"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product_cat?post=58015"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/sv\/wp-json\/wp\/v2\/product_tag?post=58015"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}