{"id":58265,"date":"2024-02-27T18:25:56","date_gmt":"2024-02-27T18:25:56","guid":{"rendered":"https:\/\/medsname.com\/lurasid\/"},"modified":"2026-04-30T10:24:16","modified_gmt":"2026-04-30T10:24:16","slug":"lurasid","status":"publish","type":"product","link":"https:\/\/medsbase.com\/sv\/product\/lurasid\/","title":{"rendered":"Lurasid"},"content":{"rendered":"

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\u26a1 Snabbt svar<\/h3>\n

Lurasid (Lurasidone 20 \/ 40 \/ 80 mg) is an atypical antipsychotic for schizophrenia and bipolar depression. Must be taken with food (\u2265 350 kcal)<\/strong> \u2014 fasting halves absorption and produces treatment failure. Metabolically among the cleanest atypicals.<\/p>\n<\/div>\n

\nVad du f\u00e5r med MedsBase:<\/strong> WHO-GMP-certifierad tillverkare \u00b7 Diskret f\u00f6rpackning \u00b7 V\u00e4rldsvid leverans \u00b7 1 400+ verifierade kundrecensioner<\/a>\n<\/div>\n

\ud83d\udce6 Varje best\u00e4llning omfattas av v\u00e5r Reshipment Assurance Policy<\/strong><\/a> \u2014 om din f\u00f6rs\u00e4ndelse inte anl\u00e4nder inom 20 arbetsdagar, skickar vi om den.<\/p>\n

Varf\u00f6r best\u00e4lla fr\u00e5n MedsBase<\/h3>\n

Lurasid at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our Reshipment Assurance Policy<\/a> \u2014 20 arbetsdagar leveranstid eller vi skickar om utan extra kostnad \u2014 och kvalificerar sig f\u00f6r v\u00e5rt kundlojalitetsprogram<\/a>. V\u00e4rldsomsp\u00e4nnande leverans \u00e4r tillg\u00e4nglig till de flesta destinationer.<\/p>\n

What Lurasid is and how it works<\/h2>\n

Lurasid is a lurasidone tablet supplied by Sun Pharma. Available strengths: 20 \/ 40 \/ 80 mg<\/strong>. Lurasidone is a D2\/5-HT2A antagonist with additional 5-HT7 antagonism (the 5-HT7 component is the basis for its bipolar-depression indication). It is one of the cleanest atypicals on metabolic markers \u2014 minimal weight gain, minimal lipid effect, minimal glucose effect.<\/p>\n

\nCRITICAL \u2014 must be taken with food (\u2265 350 kcal)<\/strong><\/p>\n

Fasting bioavailability of lurasidone is approximately half<\/strong> the fed bioavailability. Patients who skip a meal or take the dose at a small snack reach inadequate plasma levels and frequently appear to “fail” therapy. Take with the largest meal of the day, every day, at the same time.<\/strong> A glass of milk or a small biscuit is not enough \u2014 aim for at least 350 kcal of mixed-macronutrient food.<\/p>\n<\/div>\n

Indikationer och dosering<\/h2>\n\n\n\n\n\n\n\n\n\n
Indikation<\/th>\nStartdos<\/th>\nM\u00e5lgrupp<\/th>\nMax<\/th>\n<\/tr>\n<\/thead>\n
Schizofreni (vuxen)<\/td>\n40 mg OD with food<\/td>\n40\u201380 mg OD<\/td>\n160 mg<\/td>\n<\/tr>\n
Schizofreni (ungdomar \u2265 13 \u00e5r)<\/td>\n40 mg OD with food<\/td>\n40\u201380 mg OD<\/td>\n80 mg<\/td>\n<\/tr>\n
Bipolar depression (adult, monotherapy or adjunct)<\/td>\n20 mg OD with food<\/td>\n20\u201360 mg OD<\/td>\n120 mg<\/td>\n<\/tr>\n
Bipolar depression (paediatric \u2265 10 y)<\/td>\n20 mg OD with food<\/td>\n20\u201380 mg OD<\/td>\n80 mg<\/td>\n<\/tr>\n
Nedsatt njurfunktion (CrCl < 50)<\/td>\n20 mg OD with food<\/td>\nup to 80 mg<\/td>\n80 mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Viktiga s\u00e4kerhets\u00f6verv\u00e4ganden<\/h2>\n
\nFDA svart l\u00e5da \u2013 demensrelaterad psykos<\/strong><\/p>\n

Alla atypiska antipsykotiska l\u00e4kemedel b\u00e4r en FDA svart l\u00e5da-varning f\u00f6r \u00f6kad d\u00f6dlighet (fr\u00e4mst kardiovaskul\u00e4r och infektionsrelaterad) n\u00e4r de anv\u00e4nds f\u00f6r att behandla beteendest\u00f6rningar hos \u00e4ldre med demens. Atypiska antipsykotika \u00e4r inte godk\u00e4nda f\u00f6r demensrelaterad psykos eller agitation<\/strong>. Anv\u00e4ndning i denna population \u00e4r off-label, sista utv\u00e4g, tidsbegr\u00e4nsad och kr\u00e4ver explicit risk-nyttosamtal.<\/p>\n<\/div>\n

\nAkathisia and EPS<\/strong><\/p>\n

Akathisia is common at higher doses. EPS (rigidity, tremor, dystonia) less common than first-generation antipsychotics but can occur. Manageable with dose reduction or anticholinergic adjunct.<\/p>\n<\/div>\n

\nStrong CYP3A4 substrate<\/strong><\/p>\n

Avoid concurrent strong CYP3A4 inhibitors (azoles, clarithromycin, ritonavir, grapefruit juice) \u2014 they raise lurasidone levels several-fold. Avoid strong inducers (rifampicin, carbamazepine, phenytoin, St John’s wort) \u2014 they reduce levels into the ineffective range.<\/p>\n<\/div>\n

\nSuicidality (under-25, bipolar depression indication)<\/strong><\/p>\n

All antidepressant-class indications carry the under-25 suicidality warning.<\/p>\n<\/div>\n

Vanliga biverkningar<\/h2>\n