Angiplat

Product Overview

Angiplat is a medication containing the active ingredient Nitroglycerin. It is a vasodilator primarily used for the treatment of angina pectoris, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart muscle. Angiplat is available in various formulations, including sublingual tablets, sprays, and transdermal patches. This medication works by relaxing the smooth muscle in blood vessels, dilating them to improve blood flow and oxygen supply to the heart. It is commonly prescribed to relieve acute episodes of angina and to prevent angina attacks in individuals with coronary artery disease.

Uses

Angiplat is indicated for the management of angina pectoris, both stable and unstable forms. It is used to alleviate chest pain or discomfort associated with myocardial ischemia, a condition characterized by reduced blood flow to the heart muscle. Angiplat is often prescribed as a short-acting sublingual tablet or spray for the acute relief of angina attacks. Additionally, long-acting formulations such as transdermal patches may be used for the prevention of recurrent angina episodes.

How to Use

Sublingual tablets or sprays of Angiplat are administered under the tongue at the onset of angina symptoms. The tablet should be placed under the tongue and allowed to dissolve completely without chewing or swallowing. The spray should be administered onto or under the tongue as directed by a healthcare professional. For transdermal patches, the skin should be clean, dry, and hair-free before applying the patch to a non-hairy area of the chest or upper arm. Rotate patch sites to prevent skin irritation.

How it Works

Nitroglycerin, the active ingredient in Angiplat, is converted into nitric oxide (NO) in the body. Nitric oxide acts as a potent vasodilator, relaxing the smooth muscle in blood vessels and increasing their diameter. This results in the dilation of both coronary and systemic arteries, leading to improved blood flow and oxygen delivery to the heart muscle. By dilating coronary arteries, Angiplat reduces myocardial oxygen demand and relieves chest pain associated with angina pectoris.

Dosage and Administration

The dosage of Angiplat varies depending on the formulation and the severity of angina symptoms. For acute relief of angina attacks, sublingual tablets or sprays are typically administered as needed, with a recommended initial dose of 0.3 to 0.6 mg. If symptoms persist after 5 minutes, a second dose may be administered. Long-acting formulations such as transdermal patches are usually applied once daily, with dosage adjustments made based on individual patient response and tolerance.

Benefits

Angiplat offers several benefits for individuals with angina pectoris. It provides rapid relief from angina symptoms, allowing patients to resume normal activities with reduced discomfort. By improving blood flow to the heart muscle, Angiplat helps to prevent myocardial ischemia and reduce the risk of serious cardiovascular events such as heart attacks. Additionally, long-acting formulations of Angiplat offer sustained protection against angina episodes, enhancing overall quality of life for patients with coronary artery disease.

Common Side Effects

Common side effects of Angiplat may include headache, dizziness, flushing, and hypotension (low blood pressure). These side effects are usually mild and transient, resolving on their own without the need for medical intervention. However, severe headaches, fainting, or excessive hypotension may indicate a serious adverse reaction and require immediate medical attention.

Warnings

Angiplat should be used with caution in patients with hypotension, hypovolemia, or constrictive pericarditis. It is contraindicated in patients with severe anemia, increased intracranial pressure, or a history of hypersensitivity to nitroglycerin or other nitrates. Long-term use of Angiplat may lead to tolerance, necessitating dose adjustments or drug holidays to maintain efficacy. Patients should avoid sudden discontinuation of Angiplat, as rebound angina and myocardial infarction may occur.

Storage Information

Store Angiplat tablets or sprays at room temperature away from moisture and heat. Keep the medication out of reach of children and pets. Transdermal patches should be stored in their original packaging and applied immediately after opening. Do not expose transdermal patches to excessive heat or moisture, as this may affect drug potency.

Disclaimer:

Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.