Aprecap
Aprecap (Aprepitant 125/80 mg) — Cipla NK1 receptor antagonist antiemetic for prevention of acute and delayed chemotherapy-induced nausea/vomiting.
✓ Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience · Last reviewed: May 2026
Quick Answer
Aprecap — Aprepitant 125 mg/80 mg (Cipla Inc). NK1 receptor antagonist antiemetic for prevention of acute and delayed nausea/vomiting from highly and moderately emetogenic chemotherapy (cisplatin, AC, MEC). Used in combination with 5-HT3 antagonist + dexamethasone.
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⚠️ Specialist-supervised cancer therapy — this medication is started, monitored, and stopped by an oncologist or haematologist. Dosing depends on tumour type, stage, body surface area, organ function, and concomitant therapy. Self-treatment is not appropriate; the information below is educational and supports informed conversations with your specialist.
Aprepitant is a moderate CYP3A4 inhibitor. Significant interactions with dexamethasone (raises levels — dose-reduce dexamethasone 50%), warfarin (transient INR fall), oral contraceptives (efficacy reduced — use additional non-hormonal method during therapy and for 1 month after).
Frequently Asked Questions
When is this used?
NK1 receptor antagonist antiemetic for prevention of acute and delayed nausea/vomiting from highly and moderately emetogenic chemotherapy (cisplatin, AC, MEC). Used in combination with 5-HT3 antagonist + dexamethasone.
Side effects?
Class-specific — see safety boxes above. Most supportive cancer medications are well-tolerated when used per protocol but require specialist supervision.
Drug interactions?
Always disclose all medications. Cancer supportive therapy interacts with multiple cytotoxics, chemo regimens, and concomitant medications.
Pregnancy?
Variable by molecule. Consult oncology for pregnancy planning during cancer therapy.
Monitoring?
Specialist-determined — typically FBC, electrolytes, renal/liver function, cardiac monitoring as relevant.
What if I miss a dose?
Take when you remember; do not double up. Discuss with oncology team if multiple doses missed.
When is treatment finished?
Determined by clinical response, planned regimen length, and patient tolerance.
Storage?
Per package insert — typically below 25-30°C, away from light and moisture. Pregnant household members should not handle broken tablets/capsules.
Cost?
Generic Indian biosimilars and chemical equivalents are dramatically less expensive than originator products with documented bioequivalence and clinical equivalence.
Vaccines?
Coordinate with oncology — live vaccines may be contraindicated during cancer therapy.
Other Cancer & Supportive Medications
- Xeloda — capecitabine 500 mg — oral 5-FU prodrug for breast/colorectal/gastric cancers
- Altraz — anastrozole 1 mg — aromatase inhibitor for post-menopausal breast cancer
- Xbira — abiraterone 250 mg — CYP17 inhibitor for metastatic prostate cancer
- Zoldria — zoledronic acid IV — for bone metastases and hypercalcaemia
- Actorise — darbepoetin alfa — for chemotherapy-induced anaemia
More options in Anti Cancer Medication
Ranked by recent MedsBase order volume — what other customers in this category are picking.
| Strength | 125 mg |
|---|---|
| Quantity | 3 Capsule/s, 6 Capsule/s, 9 Capsule/s |
| Pharma Form | Tablet/s |
| Manufacturer | Glenmark Pharmaceuticals |
| Treatment | Nausea and vomiting due to chemotherapy |
| Generic Brand | Aprepitant |
Aprecap
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