Atrest

Product Overview

Atrest is a medication containing the active ingredient Tetrabenazine (12.5mg) in tablet form. It is primarily used in the management of movement disorders such as Huntington’s disease. Atrest works by reducing the levels of certain chemicals in the brain that are involved in the control of movement, thereby helping to alleviate symptoms associated with movement disorders.

Uses

Atrest is indicated for the treatment of chorea, a characteristic symptom of Huntington’s disease. Chorea is characterized by involuntary, irregular, jerky movements that can affect various parts of the body, including the face, arms, and legs. Atrest helps to reduce the frequency and severity of chorea episodes, improving the quality of life for individuals with Huntington’s disease.

How to Use

Atrest tablets should be taken orally as directed by a healthcare professional. The dosage may vary depending on the individual’s condition and medical history. It is usually taken two to three times daily with or without food. Swallow the tablet whole with a glass of water; do not crush, chew, or break the tablet. It is important to follow the prescribed dosage and frequency of administration to achieve optimal therapeutic effects.

How it Works

Tetrabenazine, the active ingredient in Atrest, works by inhibiting the reuptake of dopamine and norepinephrine, two neurotransmitters involved in the regulation of movement. By decreasing the levels of these neurotransmitters in the brain, Tetrabenazine helps to reduce excessive neuronal activity, which is characteristic of movement disorders such as chorea in Huntington’s disease.

Dosage and Administration

The recommended starting dosage of Atrest for the treatment of chorea associated with Huntington’s disease is 12.5mg once daily. The dosage may be titrated gradually over several weeks based on the individual’s response and tolerance to the medication. The maximum recommended dosage is 50mg per day. Dosage adjustments may be necessary in patients with hepatic impairment or those taking concomitant medications that affect hepatic enzyme activity.

Benefits

• Effectively reduces the frequency and severity of chorea episodes
• Improves overall motor function and coordination
• Enhances quality of life for individuals with Huntington’s disease
• Well-tolerated with few systemic side effects
• May help to alleviate associated symptoms such as anxiety and depression

Common Side Effects

Common side effects of Atrest may include drowsiness, dizziness, fatigue, nausea, and insomnia. Some individuals may experience parkinsonism-like symptoms such as tremor, rigidity, and bradykinesia. These side effects are usually mild to moderate in severity and tend to resolve with continued use or dosage adjustments. However, if side effects persist or worsen, consult a healthcare professional.

Warnings

Before using Atrest, inform your healthcare provider if you have a history of depression, suicidal thoughts, or liver disease. Atrest may increase the risk of depression and suicidal ideation, particularly in individuals with a predisposition to these conditions. Use caution when operating heavy machinery or performing tasks that require mental alertness, as Atrest may cause drowsiness and impair cognitive function.

Storage Information

Store Atrest tablets at room temperature (between 68°F to 77°F or 20°C to 25°C) in a tightly closed container, away from moisture and heat. Keep out of reach of children and pets. Do not use Atrest tablets beyond the expiration date printed on the packaging.

Disclaimer:

Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.