Hetrazan

Product Overview

Hetrazan is a medication containing the active ingredient Diethylcarbamazine IP. It is primarily used for the treatment of parasitic infections caused by filarial worms, including lymphatic filariasis (elephantiasis) and tropical eosinophilia. It works by immobilizing and killing the microfilariae (larval stage) of the parasites, thereby reducing their numbers in the bloodstream and alleviating symptoms associated with the infection. This medication is available in oral tablet form and is typically prescribed as part of a comprehensive treatment regimen under the supervision of a healthcare professional.

Uses

Hetrazan is indicated for the treatment of parasitic infections caused by various species of filarial worms, including Wuchereria bancrofti, Brugia malayi, and Brugia timori. It is commonly used to treat lymphatic filariasis, a debilitating condition characterized by the obstruction of lymphatic vessels and swelling of extremities. It is also effective in the management of tropical eosinophilia, a rare condition characterized by elevated levels of eosinophils in response to filarial infections.

How to Use

Hetrazan tablets should be taken orally with a full glass of water, preferably after meals to reduce gastrointestinal side effects. The dosage and duration of treatment may vary depending on the severity of the infection and the patient’s response to therapy. It is important to follow the dosage instructions provided by your healthcare provider and complete the full course of treatment as prescribed, even if symptoms improve before the medication is finished.

How it Works

Hetrazan exerts its anthelmintic (anti-parasitic) effects by disrupting the metabolism and energy production of the microfilariae, leading to their paralysis and death. This prevents the adult worms from reproducing and further spreading the infection within the host’s body. Additionally, it may modulate the host’s immune response, reducing inflammation and tissue damage associated with the parasitic infection. By targeting the microfilariae, it helps alleviate symptoms and prevent complications of filarial diseases.

Dosage and Administration

The recommended dosage of this for the treatment of filarial infections is typically 6 mg/kg body weight per day, divided into two or three doses. The duration of treatment may range from several days to several weeks, depending on the type and severity of the infection. Your healthcare provider will determine the appropriate dosage and duration of therapy based on your medical history and individual response to treatment. It is important to take it exactly as prescribed and not to exceed the recommended dosage.

Benefits

Hetrazan offers several benefits for individuals suffering from parasitic infections, including lymphatic filariasis and tropical eosinophilia. By targeting the microfilariae responsible for the infection, it helps reduce parasite burden and alleviate symptoms such as swelling, pain, and inflammation. Early initiation of treatment with it can prevent the progression of filarial diseases and minimize the risk of long-term complications, including permanent disability. Hetrazan is generally well-tolerated when used as directed under the supervision of a healthcare professional.

Common Side Effects

Common side effects of this may include nausea, vomiting, abdominal pain, diarrhea, dizziness, headache, and fatigue. These side effects are usually mild and transient, resolving with continued use or upon completion of treatment. In rare cases, allergic reactions or severe adverse effects such as liver toxicity or neurotoxicity may occur. If you experience any persistent or severe side effects while taking it, contact your healthcare provider immediately.

Warnings

Before taking it, inform your healthcare provider if you have a history of liver or kidney disease, epilepsy, or other neurological disorders. It may interact with certain medications, including anticoagulants, anticonvulsants, and antiarrhythmics, so it is important to disclose all medications you are currently taking to avoid potential drug interactions. Pregnant or breastfeeding women should use it with caution, as its safety during pregnancy and lactation has not been established.

Storage Information

Store these at room temperature away from moisture, heat, and light. Keep the medication out of reach of children and pets. Do not use expired or damaged tablets, and discard any unused portion of the medication properly according to local regulations.

Disclaimer:

Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.