⚡ Quick Answer — What is Lovegra?
Lovegra 100 mg contains sildenafil citrate as an oral tablet from Ajanta Pharma, marketed for female sexual arousal and lubrication difficulties. Important regulatory note: sildenafil is NOT FDA-approved for any female indication. Use in women is off-label. The FDA-approved medications for female hypoactive sexual desire disorder (HSDD) and female sexual arousal disorder (FSAD) are flibanserin (Addyi) and bremelanotide (Vyleesi), which work through different mechanisms. The evidence for sildenafil in women is mixed: modest benefit for SSRI-induced sexual dysfunction in women, limited benefit for general FSAD, and some benefit for arousal/lubrication in perimenopausal women without low desire. Typical dose (off-label): 50-100 mg approximately 30-60 minutes before anticipated sexual activity. Contraindications mirror male sildenafil use: absolute avoid with nitrates or guanylate cyclase stimulators, caution with cardiovascular disease, hepatic/renal impairment. Common side effects: headache, facial flushing, nasal congestion, mild dyspepsia.
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What Is Lovegra?
Lovegra is an oral sildenafil citrate 100 mg tablet from Ajanta Pharma, supplied in packs of 50 / 80 / 100 / 200 tablets. Lovegra is Ajanta Pharma’s sildenafil citrate 100 mg tablet marketed for female sexual arousal difficulties. Same active ingredient as the male Viagra / Kamagra line, offered off-label for women whose primary problem is peripheral arousal or lubrication response (rather than low desire).
Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor best known by its original brand name Viagra® (Pfizer, FDA-approved 1998 for male erectile dysfunction). The FDA has never approved sildenafil for any female indication. Nonetheless, sildenafil has been studied off-label in women for more than two decades, and some specialist clinicians prescribe it off-label for specific subsets of female sexual dysfunction. Lovegra is marketed internationally for that off-label female-sexual-health use.
Sildenafil is NOT FDA-approved for female sexual dysfunction. The FDA-approved medications for female hypoactive sexual desire disorder (HSDD) in premenopausal women are:
- Flibanserin (Addyi) — FDA-approved 2015; 5-HT1A agonist / 5-HT2A antagonist; taken daily at bedtime; works on desire, not arousal.
- Bremelanotide (Vyleesi) — FDA-approved 2019; melanocortin receptor agonist; subcutaneous injection before anticipated activity; works on desire.
These are NOT the same class as sildenafil. If your primary problem is low desire, flibanserin or bremelanotide is more likely to help than sildenafil. If your primary problem is arousal or lubrication (with desire intact), some specialist clinicians prescribe sildenafil off-label based on small-trial evidence. Speak to a clinician experienced in female sexual dysfunction before self-treating.
How Does Sildenafil Work in Women?
The female genital arousal response shares much of its physiology with the male erectile response:
- Sexual stimulation triggers nitric oxide (NO) release in female genital tissue — the clitoris, vaginal wall, and vulvar vestibule
- NO activates guanylate cyclase, raising local cGMP
- cGMP relaxes smooth muscle, increasing clitoral and vaginal blood flow, enabling vaginal lubrication and clitoral engorgement
- PDE5 is expressed in clitoral and vaginal tissue (though at lower levels than in the male corpus cavernosum). PDE5 breaks down cGMP, terminating the arousal response
- Sildenafil inhibits PDE5, prolonging the natural arousal response
Because PDE5 density is lower in female genital tissue than in the male corpus cavernosum, the magnitude of effect is typically smaller in women than in men at equivalent doses. The clinical question is whether the modest pharmacological effect translates into a meaningful subjective improvement, and the answer depends heavily on the specific female sexual dysfunction subtype.
Who May Benefit — and Who Is Unlikely To
Sildenafil in women has been studied in several specific subpopulations with different results:
- SSRI-induced sexual dysfunction — the strongest evidence for sildenafil in women. Multiple small randomised trials (most notably Nurnberg et al., JAMA 2008) found meaningful improvement in arousal, lubrication, and orgasm in women on SSRIs who developed treatment-emergent sexual dysfunction. Taken as needed before sex.
- Perimenopausal arousal / lubrication problems with intact desire — mixed evidence. Some trials show improvement; others do not. May help the subset of women whose primary problem is peripheral genital response rather than central desire.
- Female sexual arousal disorder (FSAD) with intact desire — small positive trials, but several negative trials. The effect size is modest at best.
- Hypoactive sexual desire disorder (HSDD) — low desire as the primary problem: sildenafil is unlikely to help. HSDD is a central-drive problem, not a peripheral vascular problem. Flibanserin or bremelanotide are the evidence-based options here.
- Orgasmic disorder alone — limited evidence for sildenafil; other approaches (Intrinsic Motivation Model sex therapy, mindfulness, clitoral stimulation devices) typically tried first.
Bottom line: sildenafil is a peripheral genital vasodilator. It can help women whose peripheral arousal response is blunted (e.g. on SSRIs). It does not address low desire, relationship factors, or central arousal deficits. Proper evaluation with a clinician experienced in female sexual dysfunction is the correct first step.
Lovegra Dose and How to Take
- Starting dose (off-label): 50 mg (half a 100 mg tablet) approximately 30-60 minutes before anticipated sexual activity. Because tablets are not always scored for reliable pharmacy-grade splitting, consider starting with a dedicated 50 mg product if precise dosing is needed.
- Standard dose: 100 mg (one full tablet) 30-60 minutes before activity if 50 mg produces inadequate response after 2-3 well-timed tries. Do not exceed 100 mg once per 24 hours.
- On an empty stomach or with a light meal for fastest onset. A fatty meal delays absorption by up to an hour.
- Swallow whole with water.
- Sexual stimulation is required — sildenafil enhances the natural arousal response, it does not produce arousal pharmacologically in the absence of stimulation.
- Assess response over 3-6 well-timed tries. If the first dose does not work, do not conclude the drug is ineffective — timing, setting, desire state, and stimulation quality all matter. If consistent failure across 6+ tries, sildenafil is unlikely to be the right treatment for your presentation.
Elderly (>65 years): consider starting at 25 mg. Severe hepatic impairment: reduce to 25 mg. Severe renal impairment (eGFR <30): reduce to 25 mg. Concurrent strong CYP3A4 inhibitor (ketoconazole, ritonavir, clarithromycin): start at 25 mg.
Pregnancy and breastfeeding: Pregnancy Category B (animal data reassuring, limited human data). Generally avoided in pregnancy and breastfeeding outside specialist indications (sildenafil is used in paediatric pulmonary hypertension in neonates, including during pregnancy for some foetal conditions, under specialist care).
Side Effects
Common
- Headache (10-15%)
- Facial flushing (5-10%)
- Nasal congestion (4-8%)
- Mild dyspepsia / stomach upset (5-7%)
- Visual disturbances — blue-tinted vision, light sensitivity (2-3%)
- Dizziness, mild palpitations
Less common / rare
- Back pain, muscle aches
- Allergic reactions (rash, itching)
- Transient changes in colour perception
Rare but serious — seek urgent medical attention
- Sudden vision loss (non-arteritic ischaemic optic neuropathy, NAION)
- Sudden hearing loss
- Severe cardiovascular events (MI, stroke) — very rare at therapeutic doses without underlying cardiovascular disease
- Severe allergic reaction (angioedema, anaphylaxis)
Contraindications & Warnings
- Nitrates in any form (nitroglycerin, isosorbide mono/dinitrate, amyl nitrite “poppers”) — ABSOLUTE contraindication; severe hypotension and death have occurred
- Guanylate cyclase stimulators (riociguat) — ABSOLUTE contraindication
- Recent myocardial infarction, unstable angina, severe heart failure (NYHA III-IV)
- Severe hypotension (baseline systolic BP < 90 mmHg)
- Severe hepatic impairment (reduce dose; specialist advice)
- History of NAION or retinitis pigmentosa
- Known hypersensitivity to sildenafil
- Pregnancy and breastfeeding (outside specialist indications)
- Age < 18 (not studied for female sexual dysfunction in this age group)
Drug Interactions
| Drug / class | Effect |
|---|---|
| Nitrates (any) | ABSOLUTE contraindication — severe hypotension, death |
| Alpha-blockers (doxazosin, tamsulosin) | Symptomatic hypotension — separate by 4+ hours or specialist advice |
| Strong CYP3A4 inhibitors (ketoconazole, ritonavir, clarithromycin) | Increased sildenafil levels — start at 25 mg and do not exceed 25 mg per 48 hours |
| CYP3A4 inducers (rifampin, phenytoin, carbamazepine) | Reduced sildenafil levels — may need higher dose, or different approach |
| Hormonal contraceptives | No clinically significant interaction — continue your normal contraceptive |
| SSRIs, SNRIs, bupropion | No direct PK interaction. Clinically: sildenafil is specifically used to counter SSRI-induced sexual side effects. |
| Flibanserin (Addyi) | Not formally studied in combination — specialist advice before combining |
| Alcohol | Moderate amounts (1-2 drinks) generally tolerated. Heavy alcohol amplifies hypotension and independently reduces sexual response. |
| Grapefruit / grapefruit juice | Inhibits CYP3A4; can raise sildenafil levels. Avoid during dosing. |
Storage
Store Lovegra below 25°C in the original blister pack, away from direct sunlight and humidity. Keep out of reach of children. Use before the printed expiry.
Frequently Asked Questions
Is Lovegra the “female Viagra”?
Lovegra contains the same active ingredient (sildenafil) as the original brand Viagra, marketed for women. However, sildenafil is NOT FDA-approved for any female indication. The only FDA-approved drugs specifically for female sexual dysfunction (for premenopausal HSDD) are flibanserin (Addyi) and bremelanotide (Vyleesi), which are different classes. “Female Viagra” is marketing shorthand rather than a regulatory designation.
Will Lovegra increase my sexual desire?
Unlikely — sildenafil acts peripherally on genital blood flow, not centrally on desire. If your primary problem is low desire (lack of interest in sex), sildenafil is the wrong tool. Flibanserin (Addyi) or bremelanotide (Vyleesi) are the evidence-based treatments for low desire; both address central desire circuits.
Will Lovegra help arousal or lubrication problems?
Possibly — particularly if your desire is intact but arousal/lubrication response is blunted. The strongest evidence is for women on SSRIs or SNRIs who developed treatment-emergent sexual dysfunction. For perimenopausal women with arousal/lubrication problems (not low desire), evidence is mixed. Try with a clinician who can assess whether your specific presentation is likely to respond.
Can I take Lovegra with my birth control pill?
Yes — there is no clinically significant interaction between sildenafil and hormonal contraceptives. Sildenafil does not reduce contraceptive effectiveness and contraceptives do not meaningfully affect sildenafil levels. Continue your normal birth control.
How soon before sex should I take Lovegra?
30-60 minutes before anticipated activity, on an empty stomach or with a light meal. Peak effect is around 60-90 minutes after the dose, and the useful window lasts 4-6 hours total.
Can I take Lovegra with alcohol?
Moderate alcohol (1-2 drinks) is generally tolerated. Heavy alcohol amplifies the hypotensive side effects of sildenafil and independently reduces sexual response. If alcohol is affecting your sexual experience, reducing alcohol intake will often improve response more than adding sildenafil.
What if it does not work for me?
Try 3-6 well-timed doses before concluding it is not working. If consistent failure across multiple good attempts, sildenafil is probably not the right tool for your presentation. Options to discuss with a clinician experienced in female sexual dysfunction: flibanserin (Addyi) or bremelanotide (Vyleesi) for HSDD; topical oestrogen or ospemifene for post-menopausal vaginal atrophy; testosterone (off-label, specialist use) for some specific presentations; sex therapy or couples counselling for relational factors; mindfulness-based sex therapy for attention and arousal regulation.
Is it safe to take Lovegra in pregnancy?
Generally avoid in pregnancy outside specialist indications. Pregnancy Category B (animal data reassuring but human data limited). Sildenafil is used in neonatal and obstetric specialist care (pulmonary hypertension, some foetal growth restriction trials) under close monitoring — different from routine use for sexual dysfunction. Do not self-dose in pregnancy without specialist advice.
Can I take Lovegra while on SSRIs?
Yes — this is actually the single best-evidenced use of sildenafil in women. If you are on an SSRI (sertraline, paroxetine, escitalopram, fluoxetine, citalopram) or SNRI (venlafaxine, duloxetine) and have developed treatment-emergent sexual dysfunction, sildenafil has the strongest clinical evidence for improving arousal, lubrication and orgasm. Discuss with your prescribing clinician before starting.
Where can I order Lovegra online?
You can order Lovegra from MedsBase in pack sizes of 50 / 80 / 100 / 200 tablets. Orders ship worldwide with discreet packaging. Because sildenafil for female use is off-label in all jurisdictions, speak to a clinician experienced in female sexual dysfunction before starting.
Related Products on MedsBase
- Cenforce FM (Sildenafil 100 mg) — another sildenafil variant marketed for female sexual dysfunction
- Lovegra Oral Jelly — sildenafil sachet form marketed for women
- Cenforce — standard sildenafil 25-200 mg for male erectile dysfunction
Browse the full Sildenafil category for all sildenafil products on MedsBase.
Helpful reading: MedsBase customer reviews.
Patients on Lovegra 100 mg tablets sometimes switch to Lovegra Oral Jelly (sildenafil 100 mg sachet) for the easier-to-swallow jelly format and a modestly faster onset — the active ingredient and the off-label female-arousal context are identical.
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