Avonza

Product Overview

Avonza is a medication containing the active ingredients Lamivudine (300mg), Tenofovir disoproxil fumarate (300mg), and Efavirenz (400mg) in tablet form. It is a combination antiretroviral therapy (ART) used for the treatment of human immunodeficiency virus (HIV) infection in adults and pediatric patients weighing at least 40 kg (88 lbs). Avonza helps to suppress the replication of the HIV virus, reduce viral load, and improve immune function. It is an important component of HIV treatment regimens and is typically used in combination with other antiretroviral medications.

Uses

Avonza is indicated for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 40 kg. It is used as part of a comprehensive HIV treatment regimen to control the virus, prevent disease progression, and improve the quality of life for individuals living with HIV. Avonza is not a cure for HIV infection but helps to manage the condition by reducing viral load and preserving immune function. It is important to take Avonza regularly and as prescribed by a healthcare provider to achieve optimal treatment outcomes.

How to Use

Avonza tablets should be taken orally once daily on an empty stomach, preferably at bedtime, to minimize side effects such as dizziness and central nervous system disturbances. Swallow the tablet whole with a full glass of water, and do not chew, crush, or break it. It is important to follow the dosage instructions provided by the healthcare provider and not to miss doses, as this can lead to reduced effectiveness and the development of drug resistance.

How it Works

Avonza contains a combination of antiretroviral drugs that work together to inhibit different stages of the HIV replication cycle. Lamivudine and Tenofovir disoproxil fumarate are nucleoside reverse transcriptase inhibitors (NRTIs) that interfere with the action of an enzyme called reverse transcriptase, which is essential for the replication of HIV. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that also inhibits reverse transcriptase activity. By blocking reverse transcriptase, Avonza prevents the conversion of viral RNA into DNA, thereby reducing viral load and slowing down disease progression.

Dosage and Administration

The recommended dosage of Avonza for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 40 kg is one tablet taken orally once daily. The tablet should be taken on an empty stomach, preferably at bedtime, to minimize side effects. Dosage adjustments may be necessary based on individual patient characteristics and treatment response. It is important to take Avonza regularly and at the same time each day to maintain effective drug levels in the body.

Benefits

• Effectively treats HIV-1 infection and helps to control viral replication
• Improves immune function and reduces the risk of disease progression
• Once-daily dosing regimen for convenience and improved adherence
• Combination therapy targets multiple stages of the HIV replication cycle
• Well-tolerated with manageable side effects in most patients

Common Side Effects

Common side effects of Avonza may include nausea, vomiting, diarrhea, headache, dizziness, fatigue, and rash. These side effects are usually mild to moderate in severity and may improve with continued use of the medication. However, if any side effects persist or become bothersome, it is important to inform a healthcare provider.

Warnings

Avonza may cause serious side effects, including liver problems, lactic acidosis, and central nervous system symptoms such as depression and hallucinations. Patients should be advised to seek immediate medical attention if they experience symptoms of liver problems, lactic acidosis, or central nervous system toxicity. Avonza may also interact with other medications, so it is important to inform a healthcare provider of all medications being taken.

Storage Information

Store Avonza tablets at room temperature away from moisture and heat. Keep the medication out of reach of children and pets. Do not use Avonza if the packaging is torn or shows signs of tampering.

Disclaimer:

Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.