Cetcip L
✅ Allergy symptom relief
✅ Non-drowsy formula
✅ Rapid symptom control
✅ Enhanced comfort
Contains Levocetirizine
✓ Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience · Last reviewed: May 2026
⚡ Quick Answer — What is Cetcip-L?
Cetcip-L contains levocetirizine 5 mg, the active R-isomer of cetirizine. Levocetirizine is a second-generation H1 antihistamine with rapid onset (within 1 hour), 24-hour duration, and minimal sedation. Used for allergic rhinitis, chronic urticaria, and allergic skin conditions. Once-daily dosing in the evening. Manufactured by Cipla; international brand Xyzal.
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What Is Cetcip-L?
Cetcip-L contains levocetirizine — the active R-enantiomer of cetirizine. It is more selective for H1 receptors than cetirizine, with comparable efficacy at half the milligram dose and slightly less sedation. Internationally sold as Xyzal.
How Does Levocetirizine Work?
Levocetirizine selectively binds peripheral H1 histamine receptors with high affinity. Blocking histamine relieves itch, sneezing, runny nose, watery eyes, hives, and the early-phase allergic response. Unlike first-generation antihistamines, it has minimal CNS penetration, giving negligible sedation at therapeutic doses.
Uses and Indications
- Allergic rhinitis — seasonal and perennial
- Chronic spontaneous urticaria
- Allergic conjunctivitis
- Atopic dermatitis adjunct
- Adjunct in allergic asthma with rhinitis
Cetcip-L Dosage
| Patient | Dose | Frequency |
|---|---|---|
| Adults & children >12 yr | 5 mg | Once daily in the evening |
| Children 6–11 yr | 2.5 mg | Once daily in the evening |
| Children 2–5 yr (syrup) | 1.25 mg | Once daily |
| Renal impairment (CrCl <50 ml/min) | Reduce dose 50% | Once daily |
Side Effects of Cetcip-L
- Mild drowsiness in 5–14% (better than cetirizine; worse than loratadine)
- Dry mouth
- Headache
- Mild fatigue
- Rarely: weight gain, palpitations
Serious — stop and seek help:
- Severe allergic reaction
- Severe persistent drowsiness preventing daily function
Warnings and Precautions
- Renal impairment: reduce dose; levocetirizine is renally excreted.
- Driving and machinery: usually safe — but assess individual response.
- Pregnancy and breastfeeding: reasonable safety data; loratadine has slightly more pregnancy data and is sometimes preferred.
- Allergic asthma: levocetirizine helps the rhinitis component but does not control bronchospasm.
Contraindications
- Hypersensitivity to levocetirizine or cetirizine
- End-stage renal disease (CrCl <10 ml/min)
- Severe hepatic impairment with renal impairment
Drug Interactions
- Alcohol and CNS depressants — modest additive sedation
- No significant CYP-mediated interactions
Storage
- Store below 25°C in a cool, dry place away from direct sunlight.
- Keep in original packaging until use to protect from moisture and light.
- Do not use after the expiry date printed on the strip.
- Keep out of reach of children.
Related Alternatives on MedsBase
- Alaspan — loratadine antihistamine
- Flomist Nasal Spray — fluticasone for rhinitis
- Montek Plus — montelukast + levocetirizine combo
- Budenase AQ Nasal Spray — budesonide nasal
- Asthafen — ketotifen mast-cell stabiliser
Frequently Asked Questions
Is Cetcip-L the same as Xyzal?
Yes — both contain levocetirizine 5 mg. Xyzal (UCB) is the international brand; Cetcip-L is the Cipla generic.
How is Cetcip-L different from cetirizine?
Cetirizine is the racemic mixture (50:50 R and S isomers). Cetcip-L is just the active R-isomer. Same efficacy at half the milligram dose, slightly less sedation.
How fast does Cetcip-L work?
Onset within 1 hour; full effect within 2–3 hours; duration 24 hours.
Can children take Cetcip-L?
Yes from age 2 in age-appropriate doses (1.25 mg syrup from age 2; 2.5 mg from age 6; 5 mg from age 12).
Is it safe in pregnancy?
Reasonable safety data; loratadine is sometimes preferred for more pregnancy data.
Why evening dosing?
Evening dosing minimises any daytime sedation and matches the early-morning peak of allergic symptoms.
Will Cetcip-L treat my asthma?
No — it relieves rhinitis (sneeze, itch, runny nose) but does not control asthma bronchospasm. Continue your inhalers.
Can I take Cetcip-L every day?
Yes — long-term daily use is acceptable for chronic urticaria and perennial rhinitis. No tolerance develops.
How does Cetcip-L compare to fexofenadine?
Both are non-sedating second-generation antihistamines. Fexofenadine has the lowest drowsiness rate; levocetirizine is slightly more sedating but cheaper. Both equally effective for most allergy symptoms.
More options in Asthma/COPD Treatment
Ranked by recent MedsBase order volume — what other customers in this category are picking.
| Strength | 5 mg |
|---|---|
| Quantity | 50 Tablet/s, 100 Tablet/s, 200 Tablet/s |
| Pharma Form | Tablet/s |
| Manufacturer | Cipla Inc |
| Treatment | Allergy symptoms |
| Generic Brand | Levocetirizine |
Cetcip L
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Cetcip L
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