Frontline Plus XL

✅ Effective flea control
✅ Prevents flea infestations
✅ Kills flea eggs
✅ Long-lasting protection
✅ Suitable for large dogs

Frontline Plus XL contains fipronil and methoprene.

Product Overview

Frontline Plus XL is a veterinarian-recommended medication specially formulated for dogs. It contains the active ingredients fipronil and (S)-methoprene, which work together to provide comprehensive protection against fleas, ticks, and their larvae and eggs. Frontline Plus XL comes in convenient pipettes for easy topical application, making it a reliable choice for pet owners seeking long-lasting flea and tick control for their furry companions.


Frontline Plus XL is used to effectively prevent and treat flea and tick infestations in dogs. It kills adult fleas, flea eggs, flea larvae, ticks, and chewing lice, providing both immediate relief and long-term protection. Frontline Plus XL can help alleviate itching and discomfort caused by flea bites, as well as reduce the risk of tick-borne diseases such as Lyme disease and Rocky Mountain spotted fever.

How to Use

To use Frontline Plus XL, simply remove one pipette from the package and hold it upright. Tap the narrow part of the pipette to ensure the contents are in the main body of the pipette. Snap off the tip along the scored line to open the pipette, and part the fur between your dog’s shoulder blades to expose the skin. Apply the entire contents of the pipette directly onto the skin, making sure to avoid contact with your dog’s eyes or mouth. Repeat the application monthly for continuous protection.

How it Works

Frontline Plus XL works by targeting the nervous systems of fleas and ticks upon contact. The active ingredient fipronil disrupts the normal functioning of insect nerve cells, leading to paralysis and eventual death of the pests. Additionally, (S)-methoprene acts as an insect growth regulator, preventing flea eggs and larvae from developing into adults, thus breaking the flea life cycle. This dual-action formula ensures rapid elimination of existing parasites and prevents reinfestation.

Dosage and Administration

For dogs weighing over 40kg, apply one pipette (4.02mL) of Frontline Plus XL solution directly onto the skin once a month. Ensure proper dosage by choosing the appropriate product based on your dog’s weight. Do not use Frontline Plus XL on cats or other animals, as it is formulated specifically for dogs. Consult your veterinarian for advice on the most suitable flea and tick control regimen for your pet.


  • Provides comprehensive protection against fleas, ticks, and their larvae and eggs
  • Kills adult fleas, flea eggs, flea larvae, ticks, and chewing lice
  • Offers both immediate relief and long-lasting prevention
  • Helps alleviate itching and discomfort caused by flea bites
  • Reduces the risk of tick-borne diseases in dogs

Common Side Effects

Common side effects of Frontline Plus XL may include temporary skin irritation or sensitivity at the application site. These reactions are typically mild and transient, resolving on their own without any specific treatment. However, if your dog experiences persistent irritation or other adverse effects, discontinue use and consult your veterinarian for further guidance.


Avoid contact with eyes or mouth when applying Frontline Plus XL to your dog. Do not allow children to handle treated dogs until the application site is dry. If accidental ingestion occurs, seek medical advice immediately and bring the product label or packaging for reference. Frontline Plus XL is for external use on dogs only and should not be ingested or applied to other species. Use with caution in debilitated, aged, or pregnant animals.

Storage Information

Store Frontline Plus XL in the original packaging at room temperature, away from heat and direct sunlight. Keep out of reach of children and pets. Do not store or reuse empty pipettes. Dispose of used pipettes properly according to local regulations.


Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified veterinarian. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your veterinarian and discuss all your queries related to any pet health concerns or medicines. We intend to support, not replace, the pet owner-veterinarian relationship.


1 Box, 2 Boxes, 3 Boxes, 6 Boxes


There are no reviews yet.

Be the first to review “Frontline Plus XL”