Genticyn Injection

Product Overview

Genticyn Injection is a medication containing the active ingredient Gentamicin, which belongs to the aminoglycoside class of antibiotics. It is a sterile solution for intramuscular or intravenous administration. Genticyn is primarily used to treat severe bacterial infections, including those affecting the respiratory tract, urinary tract, skin, and soft tissues. It is commonly prescribed in hospital settings for patients who require immediate and potent antimicrobial therapy.

Uses

Genticyn Injection is indicated for the treatment of serious bacterial infections caused by susceptible strains of bacteria. It is effective against a wide range of gram-negative bacteria, including Escherichia coli, Klebsiella species, Pseudomonas aeruginosa, and Proteus species. It is often used to treat infections such as pneumonia, septicemia, urinary tract infections, and complicated skin and soft tissue infections.

How to Use

Genticyn Injection is administered by a healthcare professional through intramuscular or intravenous routes. The dosage and duration of treatment depend on the severity of the infection, the patient’s age, weight, and renal function, as well as the susceptibility of the causative bacteria. The injection should be given slowly over a period of 30 minutes to minimize the risk of adverse reactions. It is important to follow the healthcare provider’s instructions carefully and complete the full course of treatment as prescribed.

How it Works

Genticyn Injection works by inhibiting bacterial protein synthesis, leading to cell death and eradication of the infection. Gentamicin binds to the bacterial ribosome, interfering with the translation of mRNA into protein. This disrupts bacterial growth and replication, ultimately resulting in bactericidal activity against susceptible bacteria.

Dosage and Administration

The dosage of it varies depending on the type and severity of the infection, as well as the patient’s age, weight, and renal function. For adults and children over 12 years of age, the usual dose is 1.5 to 2 mg/kg every 8 hours, not exceeding 5 mg/kg per day. For pediatric patients under 12 years old, the dosage is adjusted based on body weight. The injection should be administered slowly over 30 minutes to minimize the risk of toxicity.

Benefits

1. Potent broad-spectrum antibiotic effective against a wide range of gram-negative bacteria.
2. Rapid onset of action, providing prompt relief from severe bacterial infections.
3. Can be administered intramuscularly or intravenously for flexibility in treatment.
4. Suitable for use in hospitalized patients requiring immediate antimicrobial therapy.
5. Well-tolerated with minimal systemic side effects when used appropriately.

Common Side Effects

Common side effects of Genticyn Injection may include nephrotoxicity (kidney damage), ototoxicity (hearing loss), and neuromuscular blockade (muscle weakness). Other less common side effects may include nausea, vomiting, and allergic reactions such as rash or itching. Patients should be monitored closely for signs of toxicity, and dosage adjustments may be necessary based on renal function.

Warnings

Genticyn Injection should be used with caution in patients with pre-existing renal impairment, hearing loss, or neuromuscular disorders. It should not be used in patients with known hypersensitivity to aminoglycoside antibiotics. Prolonged or repeated use of it may increase the risk of nephrotoxicity and ototoxicity. The injection should be reconstituted and diluted according to the manufacturer’s instructions to avoid medication errors and adverse effects.

Storage Information

Genticyn Injection should be stored at controlled room temperature (20°C to 25°C) and protected from light. Do not freeze the medication. Keep the vials tightly closed until ready for use. Discard any unused portion of the reconstituted solution after use. Do not use it beyond the expiration date printed on the packaging.

Disclaimer:

Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.