Product Overview
Glibaheal M is a medication containing the active ingredients Glibenclamide and Metformin. It is a combination oral anti-diabetic drug used to manage type 2 diabetes mellitus. Glibenclamide belongs to the sulfonylurea class of medications and works by stimulating the release of insulin from the pancreas, thereby reducing blood sugar levels. Metformin is a biguanide medication that improves insulin sensitivity and reduces glucose production in the liver. Together, these two drugs help control blood sugar levels in patients with type 2 diabetes.
Uses
Glibaheal M is used to treat type 2 diabetes mellitus in adults when diet, exercise, and single-agent therapy with either Glibenclamide or Metformin do not provide adequate glycemic control. It helps lower blood sugar levels by increasing insulin secretion and decreasing hepatic glucose production. Glibaheal M may also improve insulin sensitivity and glucose utilization in peripheral tissues, leading to better glycemic control over time.
How to Use
Glibaheal M tablets are taken orally with meals to minimize gastrointestinal side effects. The dosage is individualized based on the patient’s glycemic response and tolerance. It is usually started at a low dose and gradually increased to achieve the desired blood glucose level. The tablets should be swallowed whole with a glass of water and should not be crushed or chewed. It is important to follow the prescribed dosing regimen and continue other lifestyle modifications such as diet and exercise while taking Glibaheal M.
How it Works
Glibenclamide stimulates the release of insulin from pancreatic beta cells by binding to sulfonylurea receptors on the cell membrane. This leads to an increase in insulin secretion, which helps lower blood glucose levels. Metformin works by reducing hepatic glucose production and increasing insulin sensitivity in peripheral tissues such as muscle and fat. Together, Glibenclamide and Metformin work synergistically to improve glycemic control in patients with type 2 diabetes mellitus.
Dosage and Administration
The recommended starting dose of it is one tablet once or twice daily, with meals. The dosage may be titrated gradually based on the patient’s blood glucose levels and response to treatment. The maximum recommended daily dose is usually two tablets taken twice daily. It is important to monitor blood glucose levels regularly and adjust the dosage as needed under the guidance of a healthcare professional.
Benefits
- Combination therapy for improved glycemic control in type 2 diabetes mellitus.
- Dual mechanism of action targeting insulin secretion and insulin sensitivity.
- Convenient oral administration with once or twice daily dosing.
- Helps lower blood glucose levels and reduce the risk of diabetes-related complications.
- May offer better control over fasting and postprandial blood sugar levels compared to monotherapy.
Common Side Effects
Common side effects of it may include hypoglycemia (low blood sugar), gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal discomfort. These side effects are usually mild and transient, but they may occur more frequently with higher doses or when starting treatment. Rarely, allergic reactions, liver function abnormalities, and lactic acidosis may occur with Metformin use.
Warnings
Glibaheal M should be used with caution in patients with impaired renal function, hepatic impairment, or a history of lactic acidosis. It is contraindicated in patients with type 1 diabetes mellitus, diabetic ketoacidosis, and severe renal or hepatic impairment. Patients should be monitored regularly for signs of hypoglycemia, particularly during dose adjustments or when using other medications that may potentiate the effects of Glibenclamide or Metformin.
Storage Information
These tablets should be stored at room temperature (20°C to 25°C) in a dry place away from moisture and heat. Keep the tablets in their original blister pack until ready for use to protect them from light and humidity. Do not store the medication in the bathroom or near the kitchen sink. Keep out of reach of children and pets.
Disclaimer:
Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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