Instgra

Product Overview

Instgra is a medication containing the active ingredient Dolutegravir. It belongs to a class of drugs known as integrase strand transfer inhibitors (INSTIs), which are used in the treatment of HIV (human immunodeficiency virus) infection. Instgra works by blocking the action of integrase, an enzyme that HIV needs to multiply and infect healthy cells. This helps to reduce the viral load in the body and slow down the progression of HIV infection. It is available in tablet form and is typically used in combination with other antiretroviral medications as part of a comprehensive HIV treatment regimen.

Uses

Instgra is primarily used for the treatment of HIV-1 infection in adults and children aged 6 years and older. It is indicated for both treatment-naive individuals and those who have previously received HIV treatment. It is effective in reducing HIV viral load, increasing CD4 cell counts, and improving immune function. By suppressing HIV replication, it helps to control the progression of HIV infection and reduce the risk of developing AIDS (acquired immunodeficiency syndrome) and its associated complications.

How to Use

Instgra tablets should be taken orally once daily with or without food. It is important to swallow the tablets whole with a full glass of water and not to crush, chew, or break them. It can be taken at any time of day, but it is recommended to take it at the same time each day to maintain consistent drug levels in the body. It is essential to follow the prescribed dosage and schedule provided by a healthcare provider. Do not skip doses or stop taking it without consulting a doctor, as this can lead to treatment failure and the development of drug-resistant HIV strains.

How it Works

The active ingredient in it, Dolutegravir, works by inhibiting the integrase enzyme, which is essential for the replication of HIV-1. By blocking integrase, it prevents the integration of viral DNA into the DNA of healthy cells, thereby halting the replication of the virus and reducing HIV viral load in the bloodstream. This helps to slow down the progression of HIV infection and preserve immune function. It is highly potent and has a high barrier to resistance, making it an important component of HIV treatment regimens.

Dosage and Administration

The recommended dosage of Instgra for the treatment of HIV-1 infection in adults and pediatric patients aged 6 years and older is 50 mg once daily. For individuals with certain drug-resistant HIV strains or other special populations, the dosage may be adjusted or administered in combination with other antiretroviral medications. It should be taken consistently at the same time each day to ensure optimal effectiveness. Dosage adjustments may be necessary in patients with renal impairment or when used concomitantly with certain medications.

Benefits

Instgra offers several benefits for individuals living with HIV infection. It effectively reduces HIV viral load, which helps to control the progression of the disease and improve immune function. Instgra is generally well-tolerated and has a favorable side effect profile compared to some other antiretroviral drugs. Its once-daily dosing regimen simplifies treatment adherence and improves patient convenience. Additionally, it has a high barrier to resistance, making it an effective long-term treatment option for HIV infection.

Common Side Effects

Common side effects of it may include headache, nausea, diarrhea, fatigue, insomnia, and abnormal dreams. These side effects are usually mild to moderate in severity and tend to improve over time as the body adjusts to the medication. Serious side effects such as hypersensitivity reactions and liver toxicity are rare but may occur. It is important to report any unusual or persistent side effects to a healthcare provider promptly.

Warnings

Instgra may cause severe or life-threatening side effects in some individuals, including allergic reactions, liver problems, and lactic acidosis. It may also interact with certain medications, including rifampin, antacids, and certain antiepileptic drugs, which can affect its efficacy or increase the risk of side effects. It should not be used during pregnancy unless the potential benefits outweigh the risks to the fetus. Pregnant individuals with HIV should consult a healthcare provider to discuss the safest and most effective treatment options.

Storage Information

Instgra tablets should be stored at room temperature between 20°C to 25°C (68°F to 77°F), away from moisture and heat. Keep the tablets in their original packaging and out of reach of children. Do not store it in the bathroom or near the kitchen sink, as moisture and humidity can affect its stability. If any unused or expired medication needs to be discarded, it should be done properly according to local regulations or guidelines.

Disclaimer:

Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.