Itrotab

Product Overview

Itrotab is a medication containing the active ingredient Itraconazole, which belongs to the class of antifungal medications known as triazole derivatives. It is used to treat a variety of fungal infections, including infections of the lungs, mouth, throat, and nails. Itrotab works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting fungal growth and replication. It is available in tablet form for oral administration.

Uses

Itrotab is primarily used for the treatment of fungal infections caused by susceptible strains of fungi, including Aspergillus, Blastomyces, Candida, Coccidioides, and Histoplasma. It is indicated for the treatment of fungal infections of the lungs (pulmonary aspergillosis), mouth and throat (oropharyngeal and esophageal candidiasis), and nails (onychomycosis). Itrotab may also be used to prevent fungal infections in immunocompromised patients, such as those with HIV/AIDS or undergoing chemotherapy.

How to Use

Itrotab tablets should be taken orally with a full glass of water, preferably with food to enhance absorption and minimize gastrointestinal side effects. The dosage and duration of treatment depend on the type and severity of the fungal infection, as well as the patient’s age, weight, and overall health condition. It is important to complete the full course of treatment as prescribed by the healthcare provider, even if symptoms improve before the medication is finished.

How it Works

Itrotab works by inhibiting the enzyme lanosterol 14-alpha-demethylase, which is involved in the synthesis of ergosterol, an essential component of fungal cell membranes. By disrupting ergosterol synthesis, Itrotab alters the permeability and integrity of fungal cell membranes, leading to leakage of cellular contents and ultimately fungal cell death. This mechanism of action is specific to fungi and does not affect mammalian cells, making Itrotab a selective antifungal agent.

Dosage and Administration

The recommended dosage of Itrotab depends on the type and severity of the fungal infection being treated. For most infections, the typical adult dosage is 100 to 200 mg once or twice daily. For the treatment of onychomycosis (fungal nail infection), a higher dosage of 200 mg twice daily for 1 week per month is often used. The duration of treatment may range from a few days to several months, depending on the response to therapy and the recurrence of infection.

Benefits

The benefits of Itrotab include its high efficacy in treating a wide range of fungal infections, including those caused by resistant strains of fungi. Itrotab is well tolerated and can be administered orally, making it convenient for patients to use at home. Itrotab offers a broad spectrum of antifungal activity, allowing for the treatment of various types of fungal infections with a single medication.

Common Side Effects

Common side effects associated with the use of Itrotab may include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain. Other common side effects may include headache, dizziness, rash, and elevated liver enzymes. These side effects are usually mild to moderate in severity and tend to resolve with continued use of the medication. However, some individuals may experience more serious side effects such as allergic reactions, liver toxicity, or heart rhythm abnormalities, which may require medical attention.

Warnings

Itrotab should be used with caution in patients with liver disease, heart disease, or electrolyte imbalances, as it may exacerbate these conditions. Itrotab may interact with certain medications, including cisapride, dofetilide, quinidine, and pimozide, leading to an increased risk of adverse effects. it is contraindicated in pregnant women and breastfeeding mothers due to the potential risk of harm to the fetus or infant. Patients should avoid consuming alcohol while taking Itrotab, as it may increase the risk of liver toxicity.

Storage Information

Itrotab tablets should be stored at room temperature between 20°C to 25°C (68°F to 77°F), away from moisture and heat. It is important to keep Itrotab out of reach of children and pets. Do not store Itrotab in the bathroom or near the kitchen sink, as moisture and humidity may affect its stability. If the medication is outdated or no longer needed, it should be disposed of properly according to local regulations.

Disclaimer:

Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.