✅ Treats acne
✅ Reduces oil production
✅ Clears skin
✅ Prevents scarring
✅ Oral medication

Accufine contains Isotretinoin.

Product Overview

Accufine is a medication containing the active ingredient Isotretinoin, a retinoid derivative of vitamin A. It is primarily used for the treatment of severe nodular acne that has not responded to other acne treatments. Accufine works by reducing the production of sebum (skin oil) and preventing the formation of acne lesions such as blackheads, whiteheads, and cysts. It is available in oral capsule form and is usually prescribed for a limited duration under the close supervision of a healthcare provider.


Accufine is indicated for the treatment of severe recalcitrant nodular acne in patients who have failed to respond to conventional acne therapies. It is reserved for cases where acne lesions are large, deep, and painful, or when they are associated with a risk of scarring or psychological distress. Accufine is not intended for the treatment of mild to moderate acne or for acne that is primarily inflammatory in nature.

How to Use

Accufine capsules should be taken orally with a full glass of water, preferably with food to enhance absorption and minimize gastrointestinal side effects. The dosage and duration of treatment are determined by the healthcare provider based on the severity of the acne, the patient’s response to therapy, and any underlying medical conditions. Accufine is usually taken once or twice daily for a period of 15 to 20 weeks, although individual treatment regimens may vary.

How it Works

Accufine works by targeting multiple factors involved in the pathogenesis of acne. It reduces the size and activity of the sebaceous glands, leading to a decrease in sebum production and secretion. Accufine also helps to normalize the process of keratinization within the hair follicles, preventing the formation of microcomedones that can develop into acne lesions. Additionally, it has anti-inflammatory properties that help to reduce inflammation associated with acne lesions and prevent the formation of new lesions.

Dosage and Administration

The recommended dosage of Accufine for the treatment of severe nodular acne is usually 0.5 to 1 mg/kg/day, divided into two doses taken with meals. The total daily dose may be adjusted based on the patient’s response to therapy and tolerability. Accufine capsules should be swallowed whole and not crushed, chewed, or opened, as this may increase the risk of irritation to the esophagus. It is important to follow the dosage instructions provided by the healthcare provider and not to exceed the prescribed dose.


The benefits of Accufine include its high efficacy in treating severe nodular acne, particularly when other acne treatments have failed. It can significantly reduce the number and severity of acne lesions, improve the appearance of the skin, and prevent the development of permanent scarring. By targeting multiple aspects of acne pathogenesis, it provides long-lasting results and helps to restore self-confidence and quality of life for individuals with severe acne.

Common Side Effects

Common side effects associated with the use of Accufine may include dry skin, dry lips, dry eyes, nosebleeds, joint pain, and muscle pain. These side effects are usually mild to moderate in severity and tend to improve with continued use of the medication. However, some individuals may experience more serious side effects such as depression, suicidal ideation, liver toxicity, or increased intracranial pressure, which may require medical attention.


Accufine is contraindicated in pregnant women due to the risk of severe birth defects, including craniofacial abnormalities, cardiovascular malformations, and central nervous system abnormalities. Female patients of childbearing age must use effective contraception before, during, and after treatment with Accufine to prevent pregnancy. It may also cause psychiatric adverse effects such as depression, mood changes, or suicidal ideation, particularly in individuals with a history of mental health disorders.

Storage Information

Accufine capsules should be stored at room temperature between 20°C to 25°C (68°F to 77°F), away from moisture and heat. It is important to keep it out of reach of children and pets. Do not store it in the bathroom or near the kitchen sink, as moisture and humidity may affect its stability. If the medication is outdated or no longer needed, it should be disposed of properly according to local regulations.


Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Additional Information


5 mg, 10 mg, 20 mg, 30 mg, 40 mg


30 Capsule/s, 60 Capsule/s, 90 Capsule/s, 180 Capsule/s


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