Nitroderm TTS

Product Overview

Nitroderm TTS is a medication containing the active ingredient Nitroglycerin. It is a transdermal therapeutic system (TTS) designed to deliver controlled doses of nitroglycerin through the skin into the bloodstream. This medication is commonly used to prevent and relieve chest pain (angina) caused by coronary artery disease. Nitroderm TTS offers a convenient and effective method of delivering nitroglycerin, providing consistent relief from angina symptoms.

Uses

Nitroderm TTS is primarily used for the treatment of angina pectoris, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart muscle. By delivering nitroglycerin directly into the bloodstream, Nitroderm TTS helps dilate blood vessels, improve blood flow to the heart, and reduce the workload on the heart, thereby relieving angina symptoms and preventing angina attacks.

How to Use

To use Nitroderm TTS, clean and dry the skin area where the patch will be applied, typically on the chest or upper arm. Remove the protective backing from the patch and press it firmly onto the skin. Rotate the application site with each new patch to minimize skin irritation. The patch should be worn continuously for 12 to 14 hours, followed by a patch-free interval of 10 to 12 hours. It is essential to follow the healthcare provider’s instructions regarding patch application and removal carefully.

How it Works

Nitroglycerin, the active ingredient in Nitroderm TTS, is a vasodilator that works by relaxing and widening blood vessels, particularly the veins. This dilation reduces the workload on the heart by decreasing the amount of blood returning to the heart and lowers blood pressure, thereby improving blood flow to the heart muscle. By increasing oxygen supply to the heart and reducing its oxygen demand, Nitroderm TTS helps alleviate chest pain associated with angina.

Dosage and Administration

The dosage of Nitroderm TTS is determined based on the severity of angina symptoms and the individual’s response to treatment. Typically, the initial dose is one patch (5 mg) applied once daily. The healthcare provider may adjust the dosage as needed to achieve optimal symptom relief while minimizing side effects. It is essential to adhere to the prescribed dosing schedule and not exceed the recommended dose to avoid the risk of tolerance and rebound angina.

Benefits

Nitroderm TTS offers several benefits in the management of angina. By delivering nitroglycerin through the skin, it provides continuous and controlled release of the medication, ensuring consistent relief from angina symptoms throughout the day. The transdermal delivery system eliminates the need for frequent dosing and allows for convenient application, enhancing patient compliance. Additionally, Nitroderm TTS helps improve exercise tolerance and quality of life in individuals with angina.

Common Side Effects

Common side effects associated with Nitroderm TTS may include headache, dizziness, flushing, and skin irritation at the patch application site. These side effects are usually mild and transient, resolving with continued use or upon patch removal. In some cases, individuals may experience low blood pressure, rapid heartbeat, or allergic reactions. Patients experiencing severe or persistent side effects should seek medical attention promptly.

Warnings

Nitroderm TTS should be used with caution in individuals with hypotension (low blood pressure), severe anemia, or hypovolemia (low blood volume). It may interact with other medications, including phosphodiesterase inhibitors (e.g., sildenafil), leading to potentially life-threatening hypotension. Patients with a history of heart attack, heart failure, or recent stroke should use Nitroderm TTS under close medical supervision. Avoid abrupt discontinuation of the patch to prevent rebound angina or other adverse effects.

Storage Information

Nitroderm TTS patches should be stored at room temperature (between 68°F and 77°F or 20°C and 25°C), away from heat and moisture. Keep the patches in their original sealed pouch until ready for use. Store them out of reach of children and pets. Do not store Nitroderm TTS patches in the refrigerator or freezer. Check the expiration date on the packaging and discard any expired patches properly.

Disclaimer:

Our sole intention is to ensure that consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. It is for informational purposes only and may not cover all possible side effects, drug interactions, or warnings. Please consult your doctor for any queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.