Vitara-V
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Vitara-V contains Vardenafil.
✓ Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience · Last reviewed: May 2026
⚡ Quick Answer — What is Vitara-V?
Vitara-V contains vardenafil and is used for erectile dysfunction. Available in 20 / 40 / 60 mg. Clinical effect lasts around 4 to 5 hours. Manufactured by Sunrise Remedies.
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Vitara-V is a vardenafil tablet used to treat erectile dysfunction. Manufactured by Sunrise Remedies, it contains the same active ingredient as Bayer’s branded Levitra® at a lower price.
Vardenafil is a selective phosphodiesterase type 5 (PDE5) inhibitor with a slightly faster onset and a tighter receptor-binding profile than sildenafil. It has a reputation for reliable response in diabetic ED and in patients who have had suboptimal results with sildenafil.
What Is Vitara-V?
Vitara-V is a prescription PDE5 inhibitor used on-demand before sexual activity. Its clinical window of 4–5 hours is similar to sildenafil, but onset can be as fast as 15–25 minutes in some patients. Vardenafil is particularly well studied in men with diabetic ED, where response rates are often higher than with other PDE5 inhibitors.
Vitara-V is most commonly prescribed for:
- Erectile dysfunction of any cause
- Diabetic ED — robust efficacy in men with diabetes
- ED unresponsive to sildenafil — vardenafil’s distinct receptor-binding profile produces a response in some non-responders
- Post-prostatectomy erectile recovery — off-label
How Does Vitara-V Work?
Vardenafil is one of the most potent PDE5 inhibitors by in-vitro receptor binding. Clinically:
- Sexual stimulation releases nitric oxide in penile tissue
- Nitric oxide activates guanylate cyclase, increasing cyclic GMP
- cGMP relaxes smooth muscle, boosting arterial inflow and trapping blood in the erectile bodies
- PDE5 breaks down cGMP, ending the erection
- Vardenafil blocks PDE5, prolonging the body’s own response to stimulation
Onset is typically 25–60 minutes, sometimes as fast as 15 minutes. Plasma half-life is about 4–5 hours. Like sildenafil, absorption is slowed by a high-fat meal, so timing matters.
Uses and Indications
- Erectile dysfunction — first-line PDE5 option, licensed in most markets
- Diabetic ED — particularly well supported by clinical data
- Post-prostatectomy rehabilitation — off-label
Vitara-V Dosage and Administration
| Scenario | Recommended Dose | Frequency / Timing |
|---|---|---|
| ED — starter dose | 10 mg | 25–60 min before activity; max 1 dose / 24 h |
| ED — inadequate response | 20 mg | Step up after 2–3 adequate trials at 10 mg |
| ED — lower sensitivity / elderly | 5 mg | Titrate upward based on tolerance |
| Mild–moderate hepatic impairment | 5 mg starter, max 10 mg | Increased levels |
| Severe renal impairment (dialysis) | 5 mg with caution | Insufficient data — specialist supervision |
| Maximum daily dose | 20 mg | Not licensed for daily dosing |
How to Take Vitara-V Properly
- Swallow whole with water — a high-fat meal can delay onset by up to 1 hour
- Allow 25–60 minutes before anticipated activity
- Do not exceed one dose per 24 hours
- Avoid grapefruit juice (CYP3A4 inhibition)
- Skip alcohol or limit to 1–2 drinks at most
Side Effects of Vitara-V
Side-effect profile is broadly similar to sildenafil and tadalafil, with some differences in frequency.
| Severity | Side Effect |
|---|---|
| Common (≥1 in 10) | Headache, facial flushing, nasal congestion |
| Common (≥1 in 100) | Dyspepsia, dizziness, back pain, nausea, visual disturbance |
| Uncommon | Palpitations, hypotension, skin rash, epistaxis, QT prolongation |
| Rare | Priapism, sudden vision loss (NAION), sudden hearing loss, myocardial infarction |
Note on QT prolongation: vardenafil has a small effect on QT interval — caution in patients on other QT-prolonging drugs (certain antiarrhythmics, macrolides, fluoroquinolones, methadone).
Warnings and Precautions
- Cardiovascular fitness for sex — sexual activity places cardiac demand on the heart. Men with active angina, recent MI (within 90 days), uncontrolled arrhythmia, or severe heart failure should have a cardiac assessment before starting a PDE5 inhibitor
- Blood pressure — PDE5 inhibitors cause mild, transient reductions in BP; use with caution if taking multiple antihypertensives
- Priapism — higher risk in men with sickle-cell disease, multiple myeloma, or leukaemia; seek urgent care if an erection lasts more than 4 hours
- Vision — discontinue and seek review if sudden visual changes occur; rare cases of non-arteritic anterior ischaemic optic neuropathy (NAION) have been reported
- Hearing — rare reports of sudden sensorineural hearing loss — stop and consult a doctor if affected
- Alcohol — significant alcohol intake combined with any PDE5 inhibitor can compound dizziness, headache, and low blood pressure
- Grapefruit juice — inhibits CYP3A4 and can raise blood levels
Contraindications — Who Should NOT Take This Medication
- Concurrent use of any nitrate — GTN, isosorbide mono/dinitrate, nicorandil, amyl nitrite (“poppers”)
- Concurrent use of guanylate cyclase stimulators such as riociguat
- Recent heart attack (within 90 days), unstable angina, or angina during intercourse
- NYHA Class II or greater heart failure within the last 6 months
- Uncontrolled arrhythmia, hypotension (BP <90/50) or uncontrolled hypertension (BP >170/100)
- Stroke within the last 6 months
- Known non-arteritic anterior ischaemic optic neuropathy (NAION) in one or both eyes
- Severe hepatic impairment (Child-Pugh C)
- Hypersensitivity to the active ingredient or any excipient
Drug Interactions
| Drug / Class | Interaction |
|---|---|
| Nitrates (GTN, ISMN, ISDN, amyl nitrite/”poppers”) | Absolute contraindication — severe, potentially fatal hypotension |
| Alpha-blockers (doxazosin, tamsulosin, alfuzosin) | Additive blood-pressure lowering — stabilise alpha-blocker dose first, start at lowest PDE5 dose |
| CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir, clarithromycin) | Raise PDE5 plasma levels — reduce dose or avoid combination |
| CYP3A4 inducers (rifampicin, phenytoin, carbamazepine, St John’s wort) | Lower PDE5 plasma levels — efficacy may be reduced |
| Riociguat and other sGC stimulators | Contraindicated — severe hypotension risk |
| Other PDE5 inhibitors | Do not combine — additive side effects without extra efficacy |
| Antihypertensives | Small additive BP reduction — usually clinically insignificant |
| Grapefruit juice | Inhibits CYP3A4 — avoid large or regular intake |
Always share a full list of your current medications, including over-the-counter products, recreational drugs, and herbal supplements, with your prescriber before starting this medication.
What to Do in Case of Overdose
Symptoms of a PDE5 overdose include severe headache, marked hypotension, dizziness, back or muscle pain, and prolonged erection. Management is supportive, with fluid resuscitation and cardiac monitoring. Contact your local poisons service or emergency department immediately if an overdose is suspected.
Storage Instructions
- Store below 30 °C in a dry place, away from direct sunlight
- Keep in the original blister packaging until use
- Keep out of reach of children and pets
- Do not use after the expiry date printed on the pack
- Dispose of unused tablets via a pharmacy take-back scheme where available
Related Alternatives on MedsBase
Looking for related ED or sexual-health treatment options?
- Modula — tadalafil 5 mg, ideal for once-daily low-dose therapy
- Vidalista — Centurion Labs tadalafil, 2.5 to 80 mg
- Tadacip — Cipla tadalafil 20 mg
- Megalis — Macleods tadalafil 10 mg / 20 mg
- Suhagra — Cipla sildenafil 25/50/100 mg
- Browse all Erectile Dysfunction treatments →
Frequently Asked Questions
How fast does Vitara-V work?
Onset is typically 25–60 minutes, occasionally as fast as 15 minutes in fasting patients. Plan at least 25 minutes before intended activity.
How long does Vitara-V last?
The clinical window is approximately 4–5 hours. Plasma half-life is about 4–5 hours.
Is vardenafil stronger than sildenafil?
In vitro, vardenafil binds PDE5 more tightly, but at equivalent clinical doses the real-world effect is broadly similar. Where vardenafil stands out is in diabetic ED and in some sildenafil non-responders.
Vitara-V vs tadalafil — which is better?
Both are effective. Vardenafil offers a shorter, tighter window (4–5 h); tadalafil offers extended cover (up to 36 h) and is licensed for daily dosing. If you want spontaneity over several days, tadalafil. If you want an on-demand session with clear on/off, vardenafil.
Is Vitara-V safer for diabetics?
Clinical data is robust for vardenafil in diabetic ED — it has consistently shown high response rates in diabetic men, who often have vascular and neurological contributors that blunt response to other agents.
Can I take Vitara-V with food?
A light meal is fine. A high-fat meal can slow onset by up to an hour — time your dose around meal content if possible.
Can I combine Vitara-V with alcohol?
Limit to 1–2 drinks. Heavy alcohol adds to vasodilation and dizziness, and it is itself a leading cause of short-term erectile difficulty.
Is Vitara-V safe with heart conditions?
Contraindicated with any nitrate, within 90 days of MI, or in unstable angina. Use with caution in patients on QT-prolonging drugs. Discuss your cardiac history with a doctor.
What if vardenafil doesn’t work for me?
Try 2–3 adequate 10 mg trials before stepping up to 20 mg. If still unsatisfactory, consider switching to tadalafil or avanafil, address reversible causes (alcohol, sleep, testosterone), or discuss combination approaches with a urologist.
Is Vitara-V licensed for once-daily use?
No — vardenafil is an on-demand medication only. For a once-daily schedule, tadalafil 5 mg (e.g. Modula) is the licensed option.
Like Vitara-V, Snovitra (vardenafil 10 mg) delivers the same vardenafil PDE5 inhibition with a 4–5 hour window — a useful low-dose option for men new to vardenafil or sensitive to higher strengths.
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