Super Avana
✅ Enhances erectile function
✅ Supports sexual performance
✅ Promotes stronger erections
✅ Generic for Stendra ® & Priligy ®
Super Avana contains Avanafil & Dapoxetine
✓ Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience · Last reviewed: May 2026
⚡ Quick Answer — What is Super Avana?
Super Avana contains avanafil 100 mg + dapoxetine 60 mg and is used for erectile dysfunction with premature ejaculation. Available in 100+60 mg (packs of 4 / 20 / 40 / 60 / 120 tablets). Clinical effect lasts around 4–6 hours for ED; 3–5 hours for PE. Manufactured by Sunrise Remedies.
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Super Avana is a dual-action tablet combining avanafil 100 mg (the fastest-onset PDE5 inhibitor currently on the market) and dapoxetine 60 mg (a short-acting SSRI for premature ejaculation). It is designed for men with co-existing ED and PE who want the quickest possible onset and the cleanest side-effect profile of the PDE5 class.
Manufactured by Sunrise Remedies, Super Avana offers the convenience of one tablet instead of two, with fixed-ratio dosing and the most selective PDE5 molecule available.
What Is Super Avana?
Super Avana contains two active ingredients that target distinct components of the male sexual response:
- Avanafil 100 mg — the newest-generation PDE5 inhibitor with the fastest onset (effects within 15 minutes), the highest PDE5 selectivity, and the cleanest side-effect profile (lower headache, flushing, and visual-disturbance rates than sildenafil or vardenafil)
- Dapoxetine 60 mg — a short-acting SSRI that extends intravaginal ejaculatory latency time (IELT) by 2–3× in men with PE
The 100 mg avanafil dose is the maximum clinical strength — used when 100 mg has proven insufficient.
How Does Super Avana Work?
The two drugs act on separate, complementary pathways:
- Avanafil selectively blocks PDE5 in penile smooth muscle, prolonging cyclic GMP activity and enabling a sustained erection in response to sexual stimulation. Its high PDE5 selectivity (PDE6/PDE11 sparing) means fewer visual disturbances and less dyspepsia than older PDE5 inhibitors
- Dapoxetine inhibits the serotonin transporter centrally, delaying the ejaculatory reflex by about 2–3× the baseline IELT
Onset is remarkably fast — avanafil begins working in as little as 15 minutes, and dapoxetine peaks around 60 minutes. Taking the tablet 30–60 minutes before intended activity aligns both windows.
Uses and Indications
- Combined ED and premature ejaculation — primary indication
- Men wanting the fastest possible PDE5 onset — avanafil’s 15-minute onset is unmatched
- Men who experienced side effects on sildenafil or vardenafil — avanafil’s cleaner profile often resolves headache, flushing, and visual-disturbance complaints
- Men on multiple medications — avanafil has fewer CYP-mediated interactions than older PDE5 inhibitors
Super Avana Dosage and Administration
| Scenario | Recommended Dose | Frequency / Timing |
|---|---|---|
| ED + PE — standard | 1 tablet (avanafil 100 mg + dapoxetine 60 mg) | 30–60 minutes before intercourse; max 1 tablet / 24 h |
| First-time use | Start with lower-strength single components if possible | 100 mg avanafil is the maximum dose — consider titrating up |
| Dose-sensitive / elderly | Separate lower-strength components | Titrate under medical guidance |
| Mild hepatic impairment | Reduced dose, with caution | Both components cleared hepatically |
| Moderate–severe hepatic impairment | Contraindicated | Dapoxetine component unsafe |
| Severe renal impairment | Not recommended | Insufficient data |
| Age >64 | Not recommended | Dapoxetine safety unproven in this population |
| Maximum daily dose | 1 tablet per 24 hours | Do not stack with other PDE5 or SSRI |
How to Take Super Avana Properly
- Swallow whole with a full glass of water — reduces syncope risk from dapoxetine
- Take 30–60 minutes before intended activity — avanafil’s fast onset gives flexibility
- Avanafil is less affected by food than sildenafil or vardenafil, but a very heavy fatty meal can still slow onset
- Do not take more than one tablet per 24 hours
- Avoid alcohol — amplifies dapoxetine-related dizziness and orthostatic hypotension
- Do not combine with additional PDE5 inhibitors or SSRIs
Side Effects of Super Avana
| Component / Severity | Side Effect |
|---|---|
| Avanafil — common | Headache, flushing, nasal congestion, back pain (generally milder than sildenafil/vardenafil) |
| Dapoxetine — common | Nausea, dizziness, headache, dry mouth, fatigue, insomnia |
| Combined — uncommon | Syncope, orthostatic hypotension, palpitations |
| Rare | Priapism, NAION, sudden hearing loss, serotonin syndrome (with other serotonergic drugs) |
Why avanafil’s side-effect profile is notable: avanafil is the most PDE5-selective molecule in the class — it spares PDE6 (retinal) and PDE11 (skeletal muscle) significantly better than sildenafil/vardenafil, which translates to fewer visual disturbances and less back/muscle pain.
Warnings and Precautions
- Cardiovascular fitness for sex — sexual activity places cardiac demand on the heart. Men with active angina, recent MI (within 90 days), uncontrolled arrhythmia, or severe heart failure should have a cardiac assessment before starting a PDE5 inhibitor
- Blood pressure — PDE5 inhibitors cause mild, transient reductions in BP; use with caution if taking multiple antihypertensives
- Priapism — higher risk in men with sickle-cell disease, multiple myeloma, or leukaemia; seek urgent care if an erection lasts more than 4 hours
- Vision — discontinue and seek review if sudden visual changes occur; rare cases of non-arteritic anterior ischaemic optic neuropathy (NAION) have been reported
- Hearing — rare reports of sudden sensorineural hearing loss — stop and consult a doctor if affected
- Alcohol — significant alcohol intake combined with any PDE5 inhibitor can compound dizziness, headache, and low blood pressure
- Grapefruit juice — inhibits CYP3A4 and can raise blood levels
Contraindications — Who Should NOT Take This Medication
- Concurrent use of any nitrate — GTN, isosorbide mono/dinitrate, nicorandil, amyl nitrite (“poppers”)
- Concurrent use of guanylate cyclase stimulators such as riociguat
- Recent heart attack (within 90 days), unstable angina, or angina during intercourse
- NYHA Class II or greater heart failure within the last 6 months
- Uncontrolled arrhythmia, hypotension (BP <90/50) or uncontrolled hypertension (BP >170/100)
- Stroke within the last 6 months
- Known non-arteritic anterior ischaemic optic neuropathy (NAION) in one or both eyes
- Severe hepatic impairment (Child-Pugh C)
- Hypersensitivity to the active ingredient or any excipient
Drug Interactions
| Drug / Class | Interaction |
|---|---|
| Nitrates (GTN, ISMN, ISDN, amyl nitrite/”poppers”) | Absolute contraindication — severe, potentially fatal hypotension |
| Alpha-blockers (doxazosin, tamsulosin, alfuzosin) | Additive blood-pressure lowering — stabilise alpha-blocker dose first, start at lowest PDE5 dose |
| CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir, clarithromycin) | Raise PDE5 plasma levels — reduce dose or avoid combination |
| CYP3A4 inducers (rifampicin, phenytoin, carbamazepine, St John’s wort) | Lower PDE5 plasma levels — efficacy may be reduced |
| Riociguat and other sGC stimulators | Contraindicated — severe hypotension risk |
| Other PDE5 inhibitors | Do not combine — additive side effects without extra efficacy |
| Antihypertensives | Small additive BP reduction — usually clinically insignificant |
| Grapefruit juice | Inhibits CYP3A4 — avoid large or regular intake |
Always share a full list of your current medications, including over-the-counter products, recreational drugs, and herbal supplements, with your prescriber before starting this medication.
What to Do in Case of Overdose
Symptoms of a PDE5 overdose include severe headache, marked hypotension, dizziness, back or muscle pain, and prolonged erection. Management is supportive, with fluid resuscitation and cardiac monitoring. Contact your local poisons service or emergency department immediately if an overdose is suspected.
Storage Instructions
- Store below 30 °C in a dry place, away from direct sunlight
- Keep in the original blister packaging until use
- Keep out of reach of children and pets
- Do not use after the expiry date printed on the pack
- Dispose of unused tablets via a pharmacy take-back scheme where available
Related Alternatives on MedsBase
Looking for related ED or sexual-health treatment options?
- Modula — tadalafil 5 mg, ideal for once-daily low-dose therapy
- Vidalista — Centurion Labs tadalafil, 2.5 to 80 mg
- Tadacip — Cipla tadalafil 20 mg
- Megalis — Macleods tadalafil 10 mg / 20 mg
- Suhagra — Cipla sildenafil 25/50/100 mg
- Browse all Erectile Dysfunction treatments →
Frequently Asked Questions
Who should take Super Avana?
Men with both erectile dysfunction and premature ejaculation who want the fastest-onset PDE5 option available, or who had intolerable side effects (headache, flushing, visual changes) on sildenafil- or vardenafil-based combinations.
How fast does Super Avana work?
Avanafil can begin working in as little as 15 minutes — the fastest onset of any PDE5 inhibitor. Dapoxetine peaks around 60 minutes. Plan 30–60 minutes before intended activity for best alignment.
How long does Super Avana last?
The ED window (avanafil) is about 4–6 hours; the PE-delay window (dapoxetine) is 3–5 hours. These overlap well for a typical single sexual encounter.
Super Avana vs Super Tadalis Sx — which is better?
Both combine an ED drug with dapoxetine. Super Avana (avanafil-based) offers the fastest onset and cleanest side-effect profile in a 4–6 hour window. Super Tadalis Sx (tadalafil-based) offers a much longer 36-hour ED window. Choose on the basis of timing: brief single encounter (this product) vs whole-weekend cover (tadalafil combo).
Can I drink alcohol with Super Avana?
Avoid alcohol. The dapoxetine component causes dizziness and fainting that alcohol significantly amplifies. Avanafil itself has milder interaction with alcohol than sildenafil, but the dapoxetine side is the limiting factor.
Does Super Avana have fewer side effects than sildenafil-based combinations?
Yes, typically. Avanafil’s high PDE5 selectivity means less headache, flushing, dyspepsia, and visual disturbance than sildenafil or vardenafil. The dapoxetine-side effects (nausea, dizziness) are the same as other dapoxetine combinations.
Is Super Avana safe if I have heart disease?
Contraindicated with nitrates, within 90 days of MI, or in unstable angina/severe heart failure. Cardiac assessment is recommended before starting any PDE5-containing medication. Avanafil has a slightly more favourable cardiac profile than older PDE5s but the same contraindications apply.
What if I only have PE (not ED)?
Use pure dapoxetine — Poxet. You don’t need the PDE5 component and adding it unnecessarily increases side-effect burden.
What if I only have ED (not PE)?
Use pure avanafil — Avana. Same fast-onset advantage without the dapoxetine-side effects.
Can I take Super Avana every day?
No — on-demand only. Max 1 tablet per 24 hours.
Are there age limits?
Not recommended above age 64 due to dapoxetine safety data limitations.
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| Strength | 100+60 mg |
|---|---|
| Quantity | 4 Tablet/s, 20 Tablet/s, 40 Tablet/s, 60 Tablet/s, 120 Tablet/s |
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