✅ Dual Diuretic Action
✅ Potassium-Sparing Formula
✅ Effective Edema Control
✅ Combats Hypertension
✅ Prevents Electrolyte Imbalance

Amifru contains Frusemide and Amiloride.

Product Overview

Amifru is a medication containing the active ingredients Frusemide and Amiloride. It is a combination diuretic used to treat fluid retention (edema) and hypertension (high blood pressure). It works by increasing urine production and reducing the amount of excess fluid and sodium in the body, thereby relieving swelling and lowering blood pressure. This medication is available in tablet form for oral administration.


Amifru is primarily used to treat conditions such as congestive heart failure, liver cirrhosis, and kidney disorders, where fluid retention and hypertension are prominent symptoms. It helps remove excess fluid from the body by increasing urine output and reducing the workload on the heart and blood vessels. Additionally, it may be prescribed to manage hypertension in patients who are not adequately controlled with other antihypertensive medications.

How to Use

These tablets should be taken orally with a full glass of water, preferably in the morning to avoid nighttime urination. It is important to follow the dosage instructions provided by the healthcare provider. The tablets can be taken with or without food, but consistency is key for optimal effectiveness. If a dose is missed, it should be taken as soon as remembered, unless it is almost time for the next scheduled dose. It is not advisable to double the dose to catch up.

How it Works

Amifru combines two diuretic agents, Frusemide and Amiloride, to achieve its therapeutic effects. Frusemide works by inhibiting the reabsorption of sodium and chloride ions in the kidney tubules, leading to increased urine production and fluid excretion. Amiloride acts on the distal renal tubules to prevent the reabsorption of potassium and hydrogen ions, thereby maintaining electrolyte balance. Together, these mechanisms help reduce fluid retention and lower blood pressure.

Dosage and Administration

The dosage of Amifru is determined by the healthcare provider based on the patient’s medical condition, kidney function, and response to treatment. Typically, the starting dose may vary from one to two tablets per day. The dosage may be adjusted gradually to achieve the desired therapeutic effect. It is important to monitor electrolyte levels, kidney function, and blood pressure regularly during treatment with it.


  1. Effectively treats fluid retention and hypertension.
  2. Reduces swelling and edema associated with heart failure and kidney disorders.
  3. Helps lower blood pressure and improve cardiovascular health.
  4. Combination therapy provides synergistic effects for better outcomes.
  5. Convenient oral administration for ease of use.

Common Side Effects

Common side effects of Amifru may include electrolyte imbalances (such as low potassium levels), dehydration, dizziness, headache, and muscle cramps. These side effects are usually mild and transient but may require medical attention if they persist or worsen. Less common but more severe side effects may include kidney dysfunction, hyperkalemia (high potassium levels), and hypotension (low blood pressure).


Amifru should be used with caution in patients with pre-existing kidney impairment, electrolyte abnormalities, or dehydration. It may interact with other medications, such as ACE inhibitors and potassium supplements, increasing the risk of hyperkalemia. It should not be used in patients with anuria (lack of urine production) or severe electrolyte imbalances. Regular monitoring of renal function, electrolyte levels, and blood pressure is recommended during it’s therapy.

Storage Information

These tablets should be stored at room temperature, away from moisture and heat. They should be kept out of reach of children and pets. Unused portions of the medication should be disposed of properly according to local regulations for pharmaceutical waste.


Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Additional Information


40 mg


30 Tablet/s, 60 Tablet/s, 90 Tablet/s, 180 Tablet/s


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