Bonair Inhaler

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What Is Bonair Inhaler?

Bonair Inhaler is a pressurised metered-dose inhaler (HFA pMDI) manufactured by Sun Pharma at WHO-GMP certified facilities. Each inhaler delivers 100 mcg per actuation of salbutamol (the international generic name is albuterol). salbutamol is on the WHO List of Essential Medicines and is the world’s most-used reliever medication for asthma and reversible airflow obstruction.

How Does Bonair Inhaler Work?

salbutamol selectively activates beta-2 adrenergic receptors on the smooth muscle that rings the bronchial airways. Receptor activation raises intracellular cyclic AMP, smooth muscle relaxes, and the airway lumen widens — this is bronchodilation. Bronchodilation begins within 1–5 minutes, peaks at 30–90 minutes, and lasts 4–6 hours. salbutamol also modestly inhibits mast-cell mediator release, reduces plasma exudation from airway capillaries, and improves mucociliary clearance.

Selectivity is dose-dependent: at therapeutic doses, β2 effects predominate; at higher systemic doses (oral tablets, repeated nebulisation), spillover onto β1 receptors causes tachycardia and palpitations, and onto β2 receptors elsewhere causes tremor and hypokalaemia.

Uses and Indications

• Acute asthma exacerbations — first-line reliever (rescue) inhaler/nebulisation
• Chronic obstructive pulmonary disease (COPD) — symptomatic relief of acute breathlessness and exercise dyspnoea
• Exercise-induced bronchoconstriction — inhaled 15–30 minutes before exercise
• Bronchospasm with allergen, cold air, or viral exposure
• Anaphylaxis with bronchospasm — adjunct to adrenaline
• Hyperkalaemia (off-label) — nebulised salbutamol drives K⁺ intracellularly

Important: Bonair Inhaler is a reliever, not a controller. It does not reduce underlying airway inflammation. Patients using more than the equivalent of one SABA canister per month, or needing a SABA more than three days per week outside of exercise pre-dosing, have poorly-controlled asthma and require step-up to inhaled corticosteroid (ICS) or ICS-LABA combination therapy.

Bonair Inhaler Dosage

How to Use Bonair Inhaler Properly

• Shake the inhaler and remove the cap.
• Breathe out fully away from the device.
• Seal lips around the mouthpiece.
• Press and inhale slowly over 3–5 seconds.
• Hold breath 10 seconds, then breathe out gently.
• Wait 30 seconds before a second puff if needed.
• Use a spacer for children, elderly, or anyone with coordination difficulty.

Side Effects of Bonair Inhaler

Common (dose-related, settle within 30–60 minutes):

• Fine tremor, especially of the hands
• Palpitations or increased heart rate (typically 10–20 bpm rise)
• Headache
• Dry mouth, throat irritation (more common with DPI/MDI)
• Muscle cramps
• Hyperactivity or agitation in young children

Less common:

• Hypokalaemia — especially with high repeat doses, worsened by theophylline, steroids or loop diuretics
• Mild hyperglycaemia
• Insomnia if dosed late evening
• Lactic acidosis with very high continuous nebulised doses (rare)

Serious (stop and seek emergency help):

• Severe allergic reaction / angio-oedema / anaphylaxis
• Paradoxical bronchospasm — worsening wheeze immediately after dose
• Cardiac arrhythmias (atrial fibrillation, supraventricular tachycardia)
• Severe hypokalaemia with arrhythmia or muscle weakness

Warnings and Precautions

• Frequent {$brand} use = poor asthma control. Needing a reliever more than 3 days per week (excluding exercise pre-dosing) means the underlying disease is not managed. Step up ICS-based controller therapy.
• Carry your reliever with you — many fatal asthma attacks happen when the inhaler is at home or expired.
• Cardiovascular disease: use cautiously in severe coronary artery disease, arrhythmias, hyperthyroidism, or severe heart failure.
• Diabetes: monitor glucose with repeat high doses.
• Pregnancy and breastfeeding: salbutamol is used at the lowest effective dose. Uncontrolled asthma is more dangerous to mother and fetus than the drug itself.
• Severe attack red flags (call emergency services): no relief 10 min after a full dose, peak flow <50% of personal best, difficulty speaking in full sentences, blue lips or drowsiness.

Contraindications

• Known hypersensitivity to salbutamol or any formulation excipient
• Tachyarrhythmias (uncontrolled) — relative contraindication
• Phaeochromocytoma — relative contraindication
• Hypertrophic obstructive cardiomyopathy — caution

Drug Interactions

Storage

• Store below 25°C, protected from direct sunlight and heat.
• Do not refrigerate. Do not freeze.
• Do not puncture the canister; even an empty canister can explode if heated.
• Keep out of reach of children. Use within the expiry date printed on the canister.

Related Alternatives on MedsBase

• Asthalin Respules — salbutamol nebuliser solution
• Budecort Inhaler — budesonide ICS preventer
• Foracort Inhaler — budesonide + formoterol ICS-LABA
• Seretide Accuhaler — fluticasone + salmeterol ICS-LABA
• Duolin Inhaler — salbutamol + ipratropium combo reliever

Frequently Asked Questions

Is Bonair Inhaler the same as Asthalin or Ventolin?

Yes — all three are 100 mcg salbutamol HFA pressurised metered-dose inhalers. Bonair is Sun Pharma’s brand; Asthalin is Cipla’s; Ventolin is GSK’s. Clinically interchangeable.

How many puffs is safe in 24 hours?

Routine: 1–2 puffs every 4–6 hours, max 8 puffs/day. Acute severe attack: up to 4–10 puffs via spacer under supervision.

When should I switch from reliever to a controller?

Needing your reliever more than three days per week (excluding pre-exercise dosing), having night symptoms more than once a month, or using more than one canister a month — any of these is a signal to add an ICS preventer.

Can I use Bonair Inhaler with a beta-blocker?

Cardioselective β1-blockers are usually OK; non-selective beta-blockers (propranolol) and timolol drops can block salbutamol and trigger severe bronchospasm — avoid where possible.

How long does Bonair Inhaler last?

A 200-actuation canister lasts about 100 days at 2 puffs per day. Track actuations or check the dose counter (if present).

Is Bonair Inhaler safe for pregnant women?

Salbutamol is widely used in pregnancy. Uncontrolled asthma is more dangerous than the drug. Use the lowest effective dose; switch to ICS-LABA controller if needed.

Why am I shaky after using Bonair Inhaler?

Fine tremor is a normal β2 effect, especially with multiple puffs. It settles in 30–60 minutes.

Can I share my inhaler with someone else?

No. The mouthpiece harbours bacteria and viruses; it should not be shared.

How do I clean Bonair Inhaler?

Once a week, remove the metal canister, rinse the plastic actuator with warm water, shake out, and air-dry overnight. Do not put the canister itself in water.

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