✅ Manages Parkinson’s symptoms
✅ Reduces tremors and stiffness
✅ Improves motor function
✅ Enhances quality of life
✅ Increases dopamine levels

Xafinact contains Safinamide.

Product Overview

Xafinact is a medication containing the active ingredient Safinamide. It belongs to a class of drugs known as monoamine oxidase inhibitors (MAOIs) and is primarily used in the treatment of Parkinson’s disease. Xafinact works by increasing the levels of dopamine in the brain, a neurotransmitter that plays a crucial role in regulating movement and coordination. By inhibiting the enzyme monoamine oxidase-B (MAO-B), Xafinact helps alleviate the symptoms of Parkinson’s disease, including tremors, stiffness, and slowness of movement.


Xafinact is indicated for use as adjunctive therapy to levodopa/carbidopa in patients with Parkinson’s disease who experience “off” episodes, characterized by a re-emergence of Parkinson’s symptoms despite optimal treatment with levodopa. It helps improve motor function and reduce the frequency and severity of “off” periods, allowing patients to maintain better control over their movements throughout the day.

How to Use

Xafinact is typically taken orally once daily, with or without food, as directed by a healthcare provider. The tablets should be swallowed whole with a glass of water and should not be crushed, chewed, or broken. It is important to follow the prescribed dosage and regimen consistently to achieve optimal therapeutic effects. Patients should not stop or change the dosage of Xafinact without consulting their healthcare provider.

How it Works

The active ingredient in Xafinact, Safinamide, works by selectively inhibiting the enzyme monoamine oxidase-B (MAO-B), which is responsible for the breakdown of dopamine in the brain. By blocking the action of MAO-B, Xafinact increases the levels of dopamine available in the brain, thereby improving the transmission of nerve impulses and restoring the balance of neurotransmitters. This helps alleviate the motor symptoms associated with Parkinson’s disease and reduces the frequency and severity of “off” episodes.

Dosage and Administration

The recommended dosage of Xafinact is typically 50 mg once daily, administered orally. The dosage may be adjusted based on individual response and tolerability, with a maximum recommended dose of 100 mg per day. Xafinact should be taken at the same time each day, and patients should not exceed the prescribed dosage without consulting their healthcare provider. It may take several weeks for patients to experience the full therapeutic benefits of Xafinact.


The primary benefit of Xafinact is its ability to improve motor function and reduce the frequency and severity of “off” episodes in patients with Parkinson’s disease. By increasing dopamine levels in the brain, Xafinact helps alleviate symptoms such as tremors, stiffness, and bradykinesia, leading to better mobility and quality of life for individuals living with Parkinson’s disease.

Common Side Effects

Common side effects associated with Xafinact may include nausea, insomnia, falls, dyskinesia, constipation, and headache. These side effects are typically mild to moderate in severity and may diminish over time as the body adjusts to the medication. However, patients should report any persistent or bothersome side effects to their healthcare provider for further evaluation and management.


Xafinact may interact with other medications, particularly those that increase serotonin levels or inhibit CYP3A4 enzymes, leading to potential adverse effects or reduced efficacy. It is important to inform healthcare providers of all medications, supplements, and herbal products being taken before starting Xafinact therapy. Additionally, patients should be monitored for the development of serotonin syndrome, orthostatic hypotension, and hallucinations while taking Xafinact.

Storage Information

Xafinact tablets should be stored at room temperature, away from moisture, heat, and direct sunlight. Keep the medication out of reach of children and pets. Do not use Xafinact beyond the expiration date printed on the packaging.


Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


50 mg, 100 mg


30 Tablet/s, 60 Tablet/s, 90 Tablet/s, 180 Tablet/s


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