Natrilix SR

Product Overview

Natrilix SR is a medication containing the active ingredient Indapamide. It belongs to a class of drugs known as diuretics or water pills. It is formulated as a sustained-release tablet, designed to gradually release the medication into the body over an extended period. This allows for once-daily dosing, providing convenient and effective management of hypertension (high blood pressure) and edema (fluid retention). By promoting diuresis (increased urine production), it helps reduce blood volume and decrease peripheral vascular resistance, ultimately leading to lower blood pressure and improved fluid balance.

Uses

Natrilix SR is primarily used for the treatment of hypertension (high blood pressure) and edema (fluid retention) associated with conditions such as congestive heart failure, liver cirrhosis, and kidney disease. It helps lower blood pressure by increasing urine output and reducing excess fluid accumulation in the body.It may be used alone or in combination with other antihypertensive agents to achieve optimal blood pressure control and reduce the risk of cardiovascular events such as stroke and heart attack.

How to Use

Natrilix SR tablets should be taken orally with a full glass of water, preferably in the morning with breakfast to minimize the risk of nocturnal diuresis (increased urination at night). The tablets should be swallowed whole and not crushed, chewed, or broken. It is important to follow the dosage instructions provided by your healthcare provider, as the dose of Natrilix SR may vary depending on the severity of your condition and your individual response to the medication. Do not stop taking Natrilix SR suddenly without consulting your doctor, as this may lead to rebound hypertension or worsening of edema.

How it Works

Indapamide, the active ingredient in Natrilix SR, is a thiazide-like diuretic that works by inhibiting the reabsorption of sodium and chloride ions in the distal convoluted tubules of the kidneys. By increasing the excretion of sodium and chloride in the urine, it promotes diuresis and helps reduce blood volume. This leads to a decrease in peripheral vascular resistance and ultimately lowers blood pressure. Additionally, Natrilix SR has mild vasodilatory effects, further contributing to its antihypertensive action.

Dosage and Administration

The recommended starting dose of Natrilix SR for the treatment of hypertension is usually 1.5 mg once daily, taken in the morning. Depending on your blood pressure response, your healthcare provider may adjust the dose up to a maximum of 2.5 mg once daily. For the management of edema, the usual starting dose is 1.5 mg once daily, which may be increased up to 5 mg once daily if necessary. Dosage adjustments may be necessary in patients with impaired renal function or electrolyte imbalances.

Benefits

1. Effective treatment for hypertension and edema.
2. Once-daily dosing with sustained-release formulation.
3. Helps lower blood pressure and reduce fluid retention.
4. May be used alone or in combination with other antihypertensive agents.
5. Reduces the risk of cardiovascular events such as stroke and heart attack.

Common Side Effects

Common side effects of Natrilix SR may include dizziness, headache, weakness, electrolyte imbalances (such as hypokalemia and hyponatremia), and increased urination. These side effects are usually mild and transient, resolving with continued use of the medication. However, if any side effects persist or worsen, contact your healthcare provider for further evaluation and management.

Warnings

Natrilix SR should be used with caution in patients with severe renal impairment, as the drug may exacerbate electrolyte imbalances. It should also be used cautiously in patients with hepatic impairment, gout, or systemic lupus erythematosus (SLE). Natrilix SR may cause orthostatic hypotension (a sudden drop in blood pressure upon standing), especially in elderly patients. Avoid driving or operating heavy machinery until you know how it affects you. Inform your healthcare provider of any other medications you are taking, as they may interact with it.

Storage Information

Store Natrilix SR tablets at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use it if the packaging is damaged or if the tablets appear discolored or deteriorated. Dispose of any unused or expired medication properly according to local regulations.

Disclaimer:

Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.