Pentasa Suppositories

✅ Rectal inflammation relief
✅ Ulcerative colitis treatment
✅ Proctitis management
✅ Mesalazine delivery
✅ Bowel inflammation reduction

Pentasa Suppositories contains Mesalazine.

Product Overview

Pentasa Suppositories contain the active ingredient Mesalazine and are designed for rectal administration. Mesalazine, also known as mesalamine, belongs to a class of medications called aminosalicylates, which are used to treat inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn’s disease. These suppositories are formulated to deliver the medication directly to the affected area in the rectum and lower part of the colon, providing targeted relief from inflammation and symptoms associated with IBD.


Pentasa Suppositories are primarily used for the treatment of mild to moderate flare-ups of ulcerative colitis, a type of IBD characterized by inflammation and ulcers in the lining of the colon and rectum. By delivering Mesalazine directly to the affected area, these suppositories help reduce inflammation, relieve symptoms such as rectal bleeding and diarrhea, and promote healing of the intestinal mucosa.

How to Use

To use Pentasa Suppositories, first, wash your hands thoroughly with soap and water. Remove the suppository from its packaging and moisten it with water to ease insertion. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Gently insert the suppository into the rectum, pointed end first. Remain lying down for a few minutes to allow the suppository to dissolve and absorb. Wash your hands again after use.

How it Works

Mesalazine, the active ingredient in Pentasa Suppositories, works locally in the colon and rectum to reduce inflammation by inhibiting the production of inflammatory mediators and promoting the release of anti-inflammatory substances. By suppressing the inflammatory response, Mesalazine helps alleviate symptoms associated with ulcerative colitis, such as abdominal pain, diarrhea, and rectal bleeding. The rectal administration of Pentasa Suppositories allows for targeted delivery of Mesalazine to the affected area, maximizing its therapeutic effect.

Dosage and Administration

The recommended dosage of Pentasa Suppositories may vary depending on the severity of the condition and individual patient response. Typically, one suppository (containing 1 g of Mesalazine) is administered rectally once daily, preferably at bedtime, or as directed by a healthcare professional. It is important to follow the prescribed dosage and administration instructions provided by your doctor to achieve the best treatment outcomes.


Pentasa Suppositories offer several benefits for individuals with ulcerative colitis or other forms of IBD. By delivering Mesalazine directly to the inflamed tissue in the rectum and lower colon, these suppositories provide targeted relief from symptoms such as rectal bleeding, diarrhea, and abdominal pain. Additionally, Pentasa Suppositories may help reduce the frequency and severity of flare-ups, leading to improved quality of life for patients with IBD.

Common Side Effects

Common side effects of Pentasa Suppositories may include mild irritation or discomfort in the rectum, mild abdominal pain, headache, and nausea. These side effects are usually temporary and resolve on their own as the body adjusts to the medication. However, if you experience persistent or severe side effects, contact your healthcare provider for further evaluation.


Pentasa Suppositories should be used with caution in patients with known allergies to Mesalazine or other aminosalicylates. It is important to inform your healthcare provider about any existing medical conditions, allergies, or medications you are taking before starting Pentasa Suppositories. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using this medication with your doctor.

Storage Information

Pentasa Suppositories should be stored at room temperature, away from moisture and heat. Keep the suppositories in their original packaging and out of reach of children and pets. Do not use Pentasa Suppositories if the packaging is damaged or if the suppositories appear discolored or deformed.


Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


1 g


7 Suppositories, 14 Suppositories, 28 Suppositories


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