Trajenta Duo

Product Overview

Trajenta Duo is a medication containing the active ingredients Linagliptin and Metformin. It is formulated to help manage type 2 diabetes mellitus by controlling blood sugar levels. Linagliptin works by increasing the levels of incretin hormones in the body, which stimulate insulin release and decrease glucagon secretion, leading to improved blood sugar control. Metformin works by reducing glucose production in the liver and improving insulin sensitivity in peripheral tissues.

Uses

Trajenta Duo is prescribed to individuals with type 2 diabetes mellitus to help lower blood sugar levels and reduce the risk of complications associated with diabetes. It is used as an adjunct to diet and exercise to improve glycemic control in adults who are unable to achieve adequate blood sugar control with diet and exercise alone. Trajenta Duo is not indicated for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.

How to Use

Trajenta Duo tablets should be taken orally with meals to reduce gastrointestinal side effects. The dosage may vary depending on individual factors such as age, renal function, and blood sugar levels. It is important to follow the dosage instructions provided by the healthcare provider. The tablets should be swallowed whole with a full glass of water and should not be chewed, crushed, or split.

How it Works

Linagliptin, one of the active ingredients in Trajenta Duo, works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which in turn increases the levels of incretin hormones. These hormones stimulate insulin release and decrease glucagon secretion, leading to improved blood sugar control. Metformin, the other active ingredient, works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues, thereby reducing blood sugar levels.

Dosage and Administration

The recommended dosage of Trajenta Duo may vary depending on individual factors such as renal function and blood sugar levels. It is typically taken twice daily with meals to reduce gastrointestinal side effects. The dosage should be adjusted based on the individual’s response to treatment and tolerability. Regular monitoring of blood sugar levels and renal function is recommended during treatment with Trajenta Duo.

Benefits

• Helps lower blood sugar levels in individuals with type 2 diabetes mellitus
• Improves glycemic control when used as an adjunct to diet and exercise
• Reduces the risk of complications associated with diabetes
• Convenient once-daily dosing regimen
• May improve insulin sensitivity and decrease insulin resistance

Common Side Effects

Common side effects of Trajenta Duo may include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal discomfort. These side effects are usually mild and transient, but individuals experiencing persistent or severe symptoms should consult their healthcare provider. In rare cases, allergic reactions or lactic acidosis may occur, and immediate medical attention should be sought if any concerning symptoms develop.

Warnings

Trajenta Duo should be used with caution in individuals with a history of kidney disease, liver disease, or heart failure, as it may exacerbate these conditions. It should not be used in individuals with severe renal impairment (eGFR <30 mL/min/1.73 m²) or acute or chronic metabolic acidosis. Trajenta Duo may also interact with certain medications, so it is important to inform the healthcare provider about all medications, supplements, and herbal products being taken.

Storage Information

Trajenta Duo tablets should be stored at room temperature away from moisture, heat, and light. Keep the tablets in their original packaging and out of reach of children and pets. Do not use Trajenta Duo tablets after the expiration date printed on the packaging.

Disclaimer:

Our sole intention is to ensure that its consumers get information that is expert-reviewed, accurate, and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions, or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.