Beclate Inhaler

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What Is Beclate Inhaler?

Beclate Inhaler is an Indian-manufactured generic pressurised metered-dose inhaler (HFA pMDI) of beclomethasone dipropionate, the same active drug used in international brand QVAR / Becotide. Each dose delivers 50, 100, 200, or 250 mcg per actuation. Cipla manufactures Beclate Inhaler at WHO-GMP certified facilities to bioequivalence standards.

How Does Beclate Inhaler Work?

beclomethasone dipropionate is a topical glucocorticoid delivered directly to the bronchial mucosa. It binds intracellular glucocorticoid receptors, translocates to the nucleus, and:

• Suppresses inflammatory gene transcription — reduces IL-4, IL-5, IL-13, TNF-α, eosinophil and lymphocyte recruitment
• Stabilises airway epithelium — reduces vascular permeability and mucus hypersecretion
• Restores β2-adrenergic receptor responsiveness — reverses tachyphylaxis to relievers
• Reduces airway hyperreactivity — fewer attacks triggered by exercise, cold air, allergens

Effect builds over 1–2 weeks of consistent twice-daily dosing. beclomethasone dipropionate has high topical potency and undergoes extensive first-pass hepatic metabolism, minimising systemic glucocorticoid effects at standard doses.

Uses and Indications

• Persistent asthma — first-line preventer at all severity levels (GINA Step 1 onward)
• Exercise-induced asthma — daily ICS reduces exercise-triggered bronchospasm
• Cough-variant asthma and eosinophilic bronchitis
• COPD with frequent exacerbations — added to LAMA + LABA when exacerbations recur (selective use; not for COPD without exacerbation history)
• Allergic asthma triggered by pollen, dust, animal dander — daily prevention through allergy season

Beclate Inhaler Dosage

How to Use Beclate Inhaler Properly

• Shake well; remove cap.
• Breathe out fully away from inhaler.
• Seal lips around mouthpiece.
• Press canister as you start a slow deep breath (3–5 seconds).
• Hold breath 10 seconds; breathe out gently.
• Wait 30 seconds between puffs.
• Rinse mouth, gargle, and spit after every dose.
• Use a spacer for children, elderly, and those with poor coordination.

Side Effects of Beclate Inhaler

Common (local, dose-related):

• Oral thrush (white candidal plaques in the mouth or throat)
• Hoarse voice / dysphonia
• Sore throat, mild cough on inhalation
• Occasional dry mouth

Less common:

• Slight reduction in growth velocity in children at higher doses (catch-up growth occurs; final adult height largely unaffected)
• Easy bruising of skin at high cumulative doses
• Possible adrenal suppression with high doses or strong CYP3A4 inhibitor co-prescription
• Cataracts and glaucoma at very high cumulative inhaled doses (rare)
• Mild weight gain (much less than with oral steroid)

Serious (stop and seek emergency help):

• Severe allergic reaction / angio-oedema
• Paradoxical bronchospasm immediately after inhalation
• Adrenal crisis during illness or surgery (rare, with high-dose long-term use)
• Pneumonia signs in COPD users (fever, productive cough, breathlessness change) — ICS slightly raises pneumonia risk in COPD

Warnings and Precautions

• {$brand} is a preventer, not a reliever. Do not use during an acute attack — use a SABA (Asthalin, Levolin) instead.
• Take it every day, even when you feel well. Effect builds over 1–2 weeks; it wears off if you skip doses.
• Rinse mouth and brush teeth after every dose to prevent thrush and hoarseness.
• Strong CYP3A4 inhibitors (ritonavir, ketoconazole, itraconazole, clarithromycin) raise systemic ICS exposure — seek alternative or monitor for Cushing-like effects.
• Do not stop suddenly after months of high-dose use — taper down to allow HPA-axis recovery.
• Pregnancy and breastfeeding: beclomethasone dipropionate is the most data-supported ICS in pregnancy (especially budesonide). Inhaled at standard doses is far safer than uncontrolled asthma.
• COPD users: ICS slightly raises pneumonia risk — ensure ICS adds value (eosinophilic phenotype, frequent exacerbations).

Contraindications

• Known hypersensitivity to beclomethasone dipropionate or any formulation excipient
• Untreated active fungal, bacterial, mycobacterial (TB), or viral respiratory infection — treat infection first
• Use with caution in active or quiescent pulmonary tuberculosis

Drug Interactions

Storage

• Store below 25°C, protected from direct sunlight and heat.
• Do not refrigerate. Do not freeze.
• Do not puncture the canister; even an empty canister can explode if heated.
• Keep out of reach of children. Use within the expiry date printed on the canister.

Related Alternatives on MedsBase

• Foracort Inhaler — budesonide + formoterol ICS-LABA combo
• Seretide Accuhaler — fluticasone + salmeterol ICS-LABA
• Asthalin Inhaler — salbutamol reliever
• Symbicort Turbohaler — budesonide + formoterol
• Montair — montelukast oral preventer

Frequently Asked Questions

How is Beclate different from Budecort?

Both are inhaled corticosteroids — Beclate (beclomethasone dipropionate) is older but well-established; Budecort (budesonide) has slightly higher topical potency and the most paediatric/pregnancy data. Either is a valid first-line preventer; choice often comes down to availability, prescriber preference, and individual response.

How long does Beclate take to work?

Some improvement within days; substantial benefit by 1 week; full effect 1–2 weeks of consistent dosing.

Why are there so many strengths?

Beclate is available in 50, 100, 200, and 250 mcg per actuation to allow precise dose titration across mild → severe asthma. Match the strength to the daily dose your doctor prescribes.

Can children use Beclate Inhaler?

Yes, from age 5 (with spacer + mask if younger). Use lowest effective dose — high cumulative ICS slightly slows growth velocity.

Is Beclate CFC-free?

Modern Beclate inhalers use HFA propellant. CFC versions were phased out worldwide by 2010. The HFA version delivers a finer particle size that reaches the small airways more effectively (so dose is sometimes halved relative to old CFC version).

Why must I rinse my mouth after Beclate?

To prevent oral thrush (candidiasis) and hoarseness — the two most common local side effects of inhaled corticosteroids.

Can I take Beclate during pregnancy?

Beclomethasone has been used in pregnancy for decades without consistent harm signal. Budesonide has more data and is the preferred ICS in pregnancy if a switch is feasible.

Should I use a spacer with Beclate?

Yes for children under 12, elderly, anyone with poor coordination, and during acute attacks. A spacer increases lung delivery 2–3× and reduces oropharyngeal deposition (less thrush, less hoarseness).

How long does a Beclate canister last?

A 200-actuation canister lasts about 50 days at 4 puffs/day. Track usage or check the dose counter.

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