Peptides

Research Peptides at MedsBase — The Complete Reference

Peptides are short chains of amino acids that act as biological signalling molecules — coordinating tissue repair, immune responses, growth-hormone release, satiety, melanocortin activity, mitochondrial function, and dozens of other physiological processes. Research peptides have become one of the most actively studied categories in modern biotech, regenerative medicine, and longevity science.

This hub is the canonical reference for the entire MedsBase peptide catalogue: it groups the 62 in-stock compounds by research goal, provides a CAS-keyed analytical table for laboratory referencing, links each molecule to its dedicated research guide, and answers the practical questions researchers actually need answered before reconstitution — sterile technique, cold-chain storage, and how to read the Certificate of Analysis that accompanies every shipment.

Pick by research goal

The fastest way to navigate a 62-compound catalogue is by the biological pathway you are studying. The seven clusters below cover every SKU on this category page.

1. Tissue repair & recovery

The most-researched cluster in regenerative peptide science. BPC‑157 is the prototype — a stable 15-amino-acid fragment of body protection compound found in gastric juice, studied for tendon, ligament, gastrointestinal, and vascular repair. TB‑500 (thymosin β‑4) is its frequent stack partner, acting on actin polymerization and angiogenesis. KPV is the α‑MSH tripeptide fragment with anti-inflammatory effects studied in colitis and skin-barrier models.

• BPC‑157 · Full research guide
• TB‑500 (Thymosin Beta-4) · Full research guide
• BPC‑157 + TB‑500 Blend · BPC vs TB: which to pick
• Peptide Healing Stack (BPC + TB + BAC)
• GLOW Blend (BPC‑157 + GHK-Cu + TB‑500)
• KPV (Lys‑Pro‑Val) · Full research guide
• Background: Best peptides for recovery — comparative analysis

2. Growth-hormone axis (GHRH & GHRP secretagogues)

These peptides stimulate endogenous growth-hormone release through two complementary mechanisms. GHRH analogues (Sermorelin, CJC‑1295, Tesamorelin) bind the GHRH receptor on pituitary somatotrophs. GHRPs / ghrelin mimetics (Ipamorelin, GHRP‑2, GHRP‑6, Hexarelin) bind the GHS-R1a receptor for amplified pulsatile release. The classical research stack pairs one of each — e.g. CJC‑1295 + Ipamorelin — for synergistic GH release with minimal cortisol/prolactin elevation. HGH 191AA is recombinant human growth hormone itself (somatropin); HGH Fragment 176‑191 is a lipolysis-selective C-terminal fragment without the growth-promoting effects of full-length GH. IGF‑1 LR3 sits downstream of GH and represents the anabolic readout.

• Sermorelin · Full research guide
• CJC‑1295 with DAC (4–8 day half-life)
• CJC‑1295 without DAC (Mod-GRF 1‑29, ~30 min half-life)
• Tesamorelin (the comparator drug, Egrifta, is FDA-approved for HIV-associated lipodystrophy — the only FDA-approved GHRH analogue)
• Ipamorelin (the cleanest GHRP for selectivity)
• GHRP‑2 Acetate · GHRP‑6 Acetate
• HGH 191AA (Somatropin)
• HGH Fragment 176‑191
• IGF‑1 LR3 · Full research guide
• Background: CJC‑1295 + Ipamorelin stack guide · Stack mechanism deep-dive

3. GLP‑1 & incretin/metabolic peptides

The most clinically advanced peptide cluster — every compound in this group has either an FDA-approved comparator drug or a Phase 2/3 trial readout. Semaglutide (comparator: Ozempic / Wegovy) is the GLP‑1 monoagonist that established the class. Tirzepatide (comparator: Mounjaro / Zepbound) adds GIP for dual-agonist weight loss. Retatrutide is the triple agonist (GLP-1 + GIP + glucagon) currently in Phase 3 with the largest weight-loss readouts to date. Mazdutide and Survodutide are dual GLP‑1/glucagon agonists. Cagrilintide is a long-acting amylin analogue typically researched alongside semaglutide (“CagriSema”).

• Semaglutide
• Tirzepatide
• Retatrutide · Mechanism guide · Research protocol · Retatrutide vs Tirzepatide
• Mazdutide
• Survodutide
• Cagrilintide
• Background: Peptide stacks for fat loss

4. Cosmetic, skin & hair-research peptides

GHK‑Cu is the prototype copper tripeptide — the most-researched cosmetic peptide, with documented effects on collagen synthesis, hair-follicle stimulation, and wound healing. AHK‑Cu is its hair-specific analogue. Melanotan II is a synthetic α‑MSH analogue studied for melanocortin-receptor pigmentation effects (and the parent compound of bremelanotide, sold separately as PT‑141 below).

• GHK‑Cu (Copper Tripeptide) · Mechanism guide · GHK-Cu for hair-loss research
• AHK‑Cu
• Melanotan II · Full research guide

5. Nootropic & CNS peptides

Short peptides studied for blood-brain barrier penetration and CNS-receptor effects. Semax and Selank are Russian-developed regulatory peptides studied for attention/anxiolysis (both built around the ACTH 4‑7 / Tuftsin motifs respectively). DSIP is delta-sleep-inducing peptide. Adamax is a research compound being investigated as a Semax follow-on.

• Semax · Full research guide
• Selank
• DSIP (Delta Sleep-Inducing Peptide)
• Adamax · Full research guide

6. Longevity & mitochondrial peptides

The newest cluster — peptides studied for cellular ageing, mitochondrial function, and telomere biology. Epitalon is the pineal-derived tetrapeptide studied for telomerase activity. NAD⁺ is the central redox cofactor whose age-related decline drives several longevity hypotheses. SS‑31 (Elamipretide) is a cardiolipin-targeted tetrapeptide with FDA orphan-drug designation for primary mitochondrial myopathy (a regulatory marker that the molecule has passed Phase 2 safety milestones, though it is not approved for general use). MOTS‑c is a mitochondrial-derived peptide encoded in the 12S rRNA gene.

• Epitalon · Full research guide
• NAD⁺ · Full research guide
• SS‑31 (Elamipretide) · Full research guide
• MOTS‑c

7. Sexual, reproductive & muscle-research peptides

PT‑141 (Bremelanotide) is the comparator molecule to FDA-approved Vyleesi for hypoactive sexual desire disorder. Kisspeptin‑10 is the upstream activator of GnRH at the hypothalamic-pituitary-gonadal axis. Oxytocin Acetate is the nonapeptide studied for social bonding and parturition. Follistatin 344 binds and neutralises myostatin, and GDF‑8 (Myostatin) itself is included for researchers studying the inhibition axis directly.

• PT‑141 (Bremelanotide) · Full research guide
• Kisspeptin‑10
• Oxytocin Acetate
• Follistatin 344
• GDF‑8 (Myostatin)

CAS-keyed A–Z reference table

Analytical reference for all 39 compounds in stock. Compounds are listed alphabetically. CAS numbers, molecular formulae, and molecular weights are provided where the compound has a formal registration; recombinant proteins and proprietary research compounds are flagged accordingly. Click any compound name to open its product page; the full Certificate of Analysis with batch-specific HPLC purity is available on request.

CAS values and molecular weights are provided for analytical/reference use. Where a compound is a recombinant protein or proprietary research compound without a single formal CAS registration, that fact is noted explicitly rather than substituted with an arbitrary identifier. Batch-specific HPLC purity (typically ≥99.0%), sequence verification, and full COA are available on request for any shipment.

Reconstitution & sterile technique

Every peptide on this page ships lyophilized (freeze-dried) under vacuum-stoppered glass. Reconstitution introduces the working solution at the concentration appropriate for the planned research dosing. Three rules cover ~95% of reconstitution problems.

1. Use bacteriostatic water, not sterile water alone, for any solution intended to be held longer than 24 hours. BAC water contains 0.9% benzyl alcohol that prevents bacterial growth in the multi-dose vial; sterile water lacks this preservative and supports microbial contamination within hours.
2. Add diluent slowly, down the side of the vial wall. Direct injection onto the lyophilized cake denatures peptide and creates clumping. After diluent contact, swirl gently — never shake. Most peptides denature on vigorous agitation. Full dissolution should take under 60 seconds; if cloudy after 5 minutes, suspect cap-seal compromise or expired diluent.
3. Calculate concentration before drawing. A 5 mg BPC-157 vial reconstituted with 2 mL BAC water = 2500 mcg/mL. On a standard insulin syringe with 100-unit / 1 mL graduation, 10 units = 0.1 mL = 250 mcg. The full reconstitution math — including how syringe markings map to peptide dose — is worked example-by-example in the BPC‑157 reconstitution & dosing calculator and the BAC water sterile-technique guide.

Storage & cold-chain protocol

Peptide stability is temperature-dependent and the working stability window differs substantially between the lyophilized and reconstituted state.

MedsBase ships in temperature-stable packaging designed to keep lyophilized vials below 25 °C across typical 5–14 day international transit. The peptide-specific courier route is the reason peptides in cat 5426 are billed under a separate $50 USD flat shipping fee rather than the standard pharmacy courier — the route uses cold-chain operators and an EU-bonded warehouse rather than the general-medication network.

What “for research use only” actually means here

None of the compounds on this page are FDA-, EMA-, or MHRA-approved for human therapeutic use. They are sold for in‑vitro laboratory research, analytical reference, and academic study only. Where a peptide has a regulatory comparator drug — for example Tesamorelin (the approved drug Egrifta, indicated for HIV-associated lipodystrophy), PT‑141 (Vyleesi, indicated for HSDD), Semaglutide (Ozempic / Wegovy), or Tirzepatide (Mounjaro / Zepbound) — that comparator is identified for clinical context only. The compound you are purchasing is not the FDA-approved finished pharmaceutical product; it is the research-grade lyophilized material.

Several compounds (SS‑31 / Elamipretide has FDA orphan-drug designation for primary mitochondrial myopathy; Retatrutide is in Phase 3 trials; Mazdutide and Survodutide are in late-stage development) have favorable regulatory trajectories but remain non-approved as of catalogue date.

Frequently asked research questions

What is the typical shipping time on peptide orders?

The dedicated peptide-courier route ships from an EU-bonded warehouse and clears most destinations within 5–14 business days. The route is separate from the general MedsBase pharmacy network — that’s why peptide orders carry a flat $50 USD shipping fee and a separate dispatch confirmation. Every order is covered by the same reshipment-assurance policy applied to all products on the site.

Are the peptides HPLC-tested? Can I see a COA?

Yes. Every batch is tested at HPLC purity threshold of ≥99.0%. The Certificate of Analysis for a specific batch — with retention times, peak integration, mass spectrometry confirmation of molecular weight, and sequence verification — is available on request. Contact support after order placement with the batch ID printed on your vial and the COA will be emailed back within one business day.

What’s the difference between CJC‑1295 with DAC and without DAC?

The “DAC” stands for Drug Affinity Complex — a maleimidopropionyl group that lets the peptide bind covalently to circulating albumin, extending half-life from ~30 minutes to roughly 4–8 days. Without-DAC CJC‑1295 (also called Mod-GRF 1‑29) produces sharp pulsatile GH release approximating endogenous pulsatility; with-DAC CJC‑1295 produces a sustained “GH bleed” elevation across days. Researchers pick based on which pulse profile they’re modelling. With-DAC is more commonly paired with Ipamorelin for sustained GH/IGF‑1 elevation studies; without-DAC is preferred where preservation of the natural pulse pattern matters.

What is the difference between Retatrutide, Tirzepatide, Semaglutide, Mazdutide, and Survodutide?

All five are incretin-class peptides differing by which receptor(s) they activate. Semaglutide — GLP‑1 receptor only (monoagonist). Tirzepatide — GLP‑1 + GIP (dual agonist). Retatrutide — GLP‑1 + GIP + glucagon (triple agonist). Mazdutide and Survodutide — GLP‑1 + glucagon (dual agonists, without the GIP arm). Trial readouts on weight-loss magnitude correlate broadly with the number of receptor arms activated. See the Retatrutide vs Tirzepatide head-to-head for direct trial comparison.

Can I stack BPC‑157 and TB‑500?

The BPC‑157 + TB‑500 stack is one of the most-researched tissue-repair combinations in peptide science — BPC‑157 acts on local growth-factor signalling and angiogenesis at the injury site, while TB‑500 acts systemically on actin polymerization and cell migration. Both products are stocked individually, as a pre-mixed blend, or as part of the Peptide Healing Stack with BAC water included. See the BPC vs TB comparison guide for mechanistic differentiation.

Why does GHK-Cu come paired with copper but other peptides don’t?

GHK is a tripeptide (glycyl-L-histidyl-L-lysine) with high copper-binding affinity. The biological activity researched in cosmetic and wound-healing models — collagen synthesis upregulation, hair-follicle stem-cell activation — depends on the Cu(II) chelated form, not the free peptide. The same logic applies to AHK-Cu. Most other peptides on this page are studied in their free-acid or acetate-salt form without metal chelation.

What does “lyophilized” mean and why does it matter?

Lyophilization (freeze-drying) is the standard preservation method for peptides — the peptide is frozen, then water is removed by sublimation under vacuum, leaving a stable solid cake. Lyophilized peptides have far longer shelf life than aqueous solutions because hydrolysis, oxidation, and microbial growth all require water. Reconstitute only the working volume you’ll use within ~30 days; keep remaining vials freezer-stored.

Can I order bacteriostatic water separately?

Yes — BAC water ships as a standalone SKU. The Peptide Healing Stack bundles BAC water with BPC‑157 + TB‑500. Standard sizes are 10 mL multi-dose vials — sufficient for several rounds of reconstitution depending on peptide concentration and study design.

Which peptide guide should I read first if I’m new to this catalogue?

For the tissue-repair cluster: BPC‑157 research guide → Best peptides for recovery. For growth-hormone: CJC‑1295 + Ipamorelin stack. For GLP-1 / metabolic: Retatrutide mechanism guide. For cosmetic / skin: GHK‑Cu deep-dive. For longevity: Epitalon & NAD⁺. For the practical reconstitution side: BAC water guide.