Hydrea
Hydrea (Hydroxyurea 500 mg) — BMS ribonucleotide reductase inhibitor for chronic myeloid leukaemia, polycythaemia vera, essential thrombocythaemia, sickle cell disease.
✓ Medicinskt granskad av Morgan Ellis — Apoteksforskare · 8 års erfarenhet · Senast granskad: maj 2026
Quick Answer
Hydrea — Hydroxyurea 500 mg (Bristol Myers Squibb). Ribonucleotide reductase inhibitor for chronic myeloid leukaemia (older first-line, now second-line after BCR-ABL TKIs), polycythaemia vera, essential thrombocythaemia, sickle cell disease, refractory cytoreduction.
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⚠️ Specialist-supervised cancer therapy — this medication is started, monitored, and stopped by an oncologist or haematologist. Dosing depends on tumour type, stage, body surface area, organ function, and concomitant therapy. Self-treatment is not appropriate; the information below is educational and supports informed conversations with your specialist.
Cumulative myelosuppression — weekly FBC initially. Cutaneous side effects: leg ulcers (especially ankles), nail/skin pigmentation, secondary skin cancers (squamous cell). Avoid in pregnancy (teratogenic) and breastfeeding.
Vanliga frågor
When is this used?
Ribonucleotide reductase inhibitor for chronic myeloid leukaemia (older first-line, now second-line after BCR-ABL TKIs), polycythaemia vera, essential thrombocythaemia, sickle cell disease, refractory cytoreduction. Specific protocols are oncologist-determined.
Biverkningar?
Class-typical: myelosuppression, nausea, alopecia, mucositis, fatigue. Specific toxicities depend on the drug — see safety boxes above.
Läkemedelsinteraktioner?
Cancer chemotherapy has multiple critical interactions. Always disclose all medications including herbals and supplements. Anticoagulants, anticonvulsants, antibiotics, antifungals, and antivirals all need review.
Graviditet?
Cytotoxic chemotherapy is teratogenic. Effective contraception during and for 6 months after for both partners.
Monitoring?
Specialist-determined — typically FBC, renal/liver function, electrolytes before each cycle. Drug-specific tests (echocardiogram for anthracyclines, audiometry for cisplatin, etc.).
Vad händer om jag missar en dos?
Oral cytotoxics: skip the missed dose, do not double up, contact your oncology team. IV: dosing is strictly scheduled — discuss any delay or missed cycle with the specialist.
Förvaring?
Oral cytotoxics: at room temperature, away from children, in original blister. Hand washing after handling tablets. Pregnant household members should not handle broken tablets.
Vaccines?
Live vaccines are contraindicated during chemotherapy. Inactivated vaccines (annual influenza, pneumococcal) are recommended. Coordinate with oncology for timing.
Long-term complications?
Class-dependent: secondary malignancy, infertility, cardiotoxicity, neuropathy. Discuss with oncology — fertility preservation may be relevant before starting.
When is treatment finished?
Determined by tumour response, treatment intent (curative vs palliative), and toxicity. Imaging and clinical assessment guide ongoing therapy.
Other Cancer Medications
- Xeloda — capecitabine 500 mg — oral 5-FU prodrug for breast/colorectal/gastric cancers
- Altraz — anastrozole 1 mg — aromatase inhibitor for post-menopausal breast cancer
- Xbira — abiraterone 250 mg — CYP17 inhibitor for metastatic prostate cancer
- Zoldria — zoledronic acid IV — for bone metastases and hypercalcaemia
- Actorise — darbepoetin alfa — for chemotherapy-induced anaemia
More options in Anti Cancer Medication
Rangerade efter senaste ordervolym på MedsBase — vad andra kunder i denna kategori väljer.
| Styrka | 500 mg |
|---|---|
| Kvantitet | 30 Kapsel/s, 60 Kapsel/s, 90 Kapsel/s |
| Farmaceutisk form | Kapsel/er |
| Tillverkare | Sarabhai Chemicals |
| Behandling | Resistant chronic myeloid leukemia |
| Generiskt märke | Hydroxyurea |
Hydrea
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Hydrea
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