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Ketosteril

✅ Enhances kidney function
✅ Reduces uremic symptoms
✅ Improves protein metabolism
✅ Lowers serum creatinine
✅ Manages chronic kidney disease

Artikelnummer: Ketosteril Kategori: , ,

Medicinskt granskad av Morgan Ellis — Apoteksforskare · 8 års erfarenhet  · Senast granskad: maj 2026

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Quick Answer

Ketosteril innehåller ketoanalogues + essential amino acids 630 mg made by Fresenius Kabi. It is used for nutritional support in chronic kidney disease (CKD) when used alongside a low-protein diet to delay disease progression and reduce uraemic symptoms. Take exactly as directed by your clinician — do not adjust the dose yourself.

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⚠ Important — this is a supplement, not an alpha-blocker or BPH medicine

Ketosteril is a renal nutritional supplement, not a treatment for an enlarged prostate or overactive bladder. It is used in adults with stage 3–5 CKD on a protein-restricted diet (~0.4–0.6 g/kg/day). If you are looking for a medicine for prostate or bladder symptoms, please use the alternatives panel at the bottom of this page.

What Ketosteril is and how it works

Ketosteril contains a fixed mix of ketoanalogues (nitrogen-free analogues of essential amino acids) and a smaller amount of essential amino acids. In CKD, dietary protein restriction reduces uraemic toxin generation but risks malnutrition. The ketoanalogues let the body manufacture amino acids by adding the patient’s own circulating nitrogen waste — so essential nutrition is preserved while urea load and uraemic symptoms (nausea, fatigue, itch) drop.

The combination is designed for use alongside a low-protein diet (typically 0.4–0.6 g/kg/day under dietitian supervision). It is not effective and may even worsen things on a normal-protein diet because excess nitrogen is then loaded back in.

Dose and how to take it

Patient groupRecommended dose
Adults > 70 kg with stage 3–5 CKD on low-protein diet4–8 tablets three times daily with main meals (12–24 tablets/day) per dietitian / nephrologist plan
Adults 40–70 kg1 tablet per 5 kg body weight per day, divided across meals
Children > 3 years (specialist supervision)1 tablet per 5 kg/day
End-stage CKD on dialysisSpecialist-guided; usually combined with intradialytic protein matching

Swallow whole with the main meal so the amino acids are available alongside dietary nitrogen sources. Do not crush or chew. Tablets are large; some users prefer to space them through a meal rather than take all at once. Ensure you are also drinking enough water unless your nephrologist has restricted fluids.

Övervakning

  • Serum calcium — ketoanalogues contain calcium; check at baseline and every 1–3 months. Stop if hypercalcaemia (> 2.6 mmol/L)
  • Serum phosphate, PTH, eGFR, BUN/urea — routine CKD monitoring
  • Body weight, MUAC and dietary protein intake — via dietitian to confirm adequate nutrition is maintained
  • Albumin, prealbumin — if malnutrition is suspected

Biverkningar

Side effectFrekvensAnteckningar
HyperkalcemiUncommon — stop if > 2.6 mmol/LCheck calcium periodically
GI upset (nausea, fullness)Common at firstTake with food; spread doses
ConstipationOvanligaAdequate fluid (within renal limits) and fibre
Hypersensitivity (rash, itch)SällsyntStop and review

Läkemedelsinteraktioner

CombinationEffektAction
Aluminium-containing antacidsCalcium can increase aluminium absorptionAvoid concurrent dosing — separate by 2 hours
Tetracyclines, fluoroquinolones, levothyroxine, oral iron, bisphosphonatesCalcium chelation reduces absorption of co-doseSeparate by 2 hours
Cardiac glycosides (digoxin)High calcium increases digoxin sensitivityMonitor; do not start concurrent calcium supplements
Vitamin D analogues, calcium supplementsAdditive risk of hypercalcaemiaSpecialist supervision

Who should not take Ketosteril

  • Hypercalcaemia (corrected serum calcium > 2.6 mmol/L)
  • Disorders of amino-acid metabolism (e.g. maple syrup urine disease, hereditary phenylketonuria)
  • Patients NOT on a structured low-protein diet (no benefit and possible nitrogen overload)
  • Severe galactose intolerance / Lapp lactase deficiency (excipient)
  • Hypersensitivity to any constituent

Vanliga frågor

Is Ketosteril a treatment for prostate or bladder problems?

No. It is a kidney-disease nutritional supplement — ketoanalogues plus essential amino acids — for use with a low-protein diet to delay CKD progression and reduce uraemic symptoms. Bladder/prostate medications are listed in the alternatives panel at the bottom of this page.

How does the low-protein diet plus Ketosteril actually slow CKD?

Less dietary nitrogen means less urea generation; the kidneys handle less waste; glomerular hyperfiltration drops. Adding ketoanalogues lets the body still build essential amino acids using circulating nitrogen waste, so nutritional status stays adequate. Trials show eGFR decline slows in stages 3–5 CKD on a structured protein-restricted diet plus ketoanalogues.

How many tablets per day?

Roughly 1 tablet per 5 kg of body weight per day, divided across the three main meals. A 70 kg adult typically takes 4–5 tablets at each meal (~12–14/day). Your nephrologist or dietitian will fine-tune.

Why with meals?

Ketoanalogues need an immediate source of nitrogen to be converted into essential amino acids. Taking them with meals provides that nitrogen and improves bioavailability.

Will I gain weight or muscle from this?

Ketosteril provides amino-acid building blocks but is not a high-calorie supplement. Maintenance of weight and muscle on a low-protein diet depends on adequate calories overall. A renal dietitian will plan calories around the protein restriction.

What about dialysis — do I still need it?

Most haemodialysis programmes match a more liberal dietary protein intake (1.0–1.2 g/kg/day) to dialysate amino-acid losses. Specialist supervision is needed; do not self-adjust.

Can I stop my phosphate binder?

No. Ketosteril does not bind dietary phosphate. Continue your prescribed binder (sevelamer, calcium acetate, lanthanum) at meal times unless your nephrologist says otherwise.

How is calcium measured and watched?

Corrected serum calcium is checked at baseline and every 1–3 months. If it rises above 2.6 mmol/L, the dose is reduced or stopped. Avoid concurrent calcium supplements unless your specialist directs.

Are there alternatives if I cannot tolerate Ketosteril?

Yes — structured low-protein diets without ketoanalogues, or alpha-keto acid mixtures with different ratios. The decision is individualised; ask your renal dietitian.

What other meds should I separate from this?

Tetracyclines, fluoroquinolones, levothyroxine, oral iron, bisphosphonates and aluminium-containing antacids should be taken at least 2 hours apart from Ketosteril because of calcium chelation.

Other Bladder & Prostate Medications

Medicinsk ansvarsfriskrivning. The information on this page is for general educational purposes only and is not a substitute for advice from a qualified clinician. Discuss any new medication or dose change with your doctor or pharmacist, especially if you are pregnant, breastfeeding, have other medical conditions, or take other medicines.

Fler alternativ i Bladder Prostate

Rangerade efter senaste ordervolym på MedsBase — vad andra kunder i denna kategori väljer.

Kvantitet

100 Tablet/s, 200 Tablet/s, 300 Tablet/s

Farmaceutisk form

Tabletter

Tillverkare

Fresenius Kabi

Behandling

Chronic Kidney Disease in the predialysis period

Generiskt märke

Ketoanalogues + Essential Amino Acids

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