⚡ Quick Answer — What is Alphagan P Drop?
Alphagan P Drop is brimonidine 0.15%, an alpha-2 adrenergic agonist eye drop that lowers eye pressure ~20% by reducing aqueous production AND increasing uveoscleral outflow. Three times daily dosing. Caution in children — avoid in age < 2 years (apnoea risk).
📦 Minden rendelést fedez a Újraküldési Garancia — ha a csomagod nem érkezik meg 20 munkanapon belül, újraküldjük.
Miért rendelj a MedsBase-ról
Alphagan P Drop is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our Újraküldési Garancia — ha 20 munkanapon belül nem érkezik meg, ingyenesen újraküldjük. Több mint 1400 hitelesített vásárlói vélemény támasztja alá.
What is Alphagan P Drop?
Alphagan P Drop is manufactured by Allergan and contains brimonidine tartrate 0.15% as a sterile ophthalmic solution. Brimonidine is a highly selective alpha-2 adrenergic agonist used to lower IOP in open-angle glaucoma and ocular hypertension. It has a unique dual mechanism — reducing aqueous humour production AND increasing uveoscleral outflow — and is one of the few glaucoma drops with a possible neuroprotective effect on retinal ganglion cells suggested by laboratory and small-cohort clinical evidence.
Hogyan működik
Brimonidine activates alpha-2 receptors on the ciliary body, decreasing cAMP and reducing aqueous production. It also increases uveoscleral outflow. Average IOP reduction is 18–22%. The 0.15% formulation (Alphagan P) uses a Purite preservative system that breaks down in the tear film into water, oxygen, and chloride ions, making it gentler than benzalkonium chloride for long-term use.
Indikációk és adagolás
| Agoprex is a 25 mg agomelatine tablet supplied by Sun Pharma. Agomelatine is mechanistically unique among antidepressants: it acts as an agonist at melatonin MT1 and MT2 receptors and an antagonist at 5-HT2C serotonin receptors. The dual mechanism resynchronises disrupted circadian rhythms (a feature of major depression) while indirectly increasing dopamine and noradrenaline release in the frontal cortex. | Dose |
|---|---|
| Open-angle glaucoma / ocular hypertension | 1 drop in affected eye(s) three times daily (every 8 hours) |
| Kiegészítő terápia | Twice daily |
| Post-laser (LPI, SLT) IOP spike prophylaxis | 1 drop pre-procedure and 1 drop post-procedure |
Mellékhatások
Local (10–20%): conjunctival hyperaemia, allergic conjunctivitis (typically appears at 6–18 months — characteristic late onset), follicular conjunctivitis, eye pruritus, foreign body sensation, blurred vision.
Rendszeres: dry mouth, fatigue, drowsiness, headache, hypotension. Children (especially under 6) can develop somnolence and bradycardia.
Figyelmeztetések és ellenjavallatok
- Children < 2 years — absolute contraindication (apnoea risk)
- Children 2–6 years — use only with caution and supervision
- Concurrent MAO inhibitors — relative contraindication, additive sedation
- Súlyos szív- és érrendszeri betegség, ortosztatikus hypotónia
- Concurrent CNS depressants (alcohol, sedatives, opioids) — additive sedation
- Terhesség/szoptatás – konzultáljon szakorvossal
Tárolás
15–25°C között, fénytől védve tároljuk. Az első nyitás után 28 nappal dobja el.
Gyakran Ismételt Kérdések
Why does Alphagan P Drop cause an allergic reaction late?
Brimonidine is one of the few glaucoma drops with classic late-onset allergic conjunctivitis — typically appearing 6–18 months into therapy. If your eyes start to feel itchy and red months after a smooth start, this is the likely cause. Stop the drop and discuss alternatives.
Is Alphagan P Drop neuroprotective?
Some preclinical and small clinical studies suggest brimonidine may protect retinal ganglion cells beyond the IOP-lowering effect. The Low-Pressure Glaucoma Treatment Study (LoGTS) showed less visual-field progression on brimonidine vs timolol despite equivalent IOP control. The evidence is suggestive rather than definitive.
Why three times a day?
Brimonidine has an 8-hour duration of action. Three-times-daily dosing maintains 24-hour IOP control as monotherapy. As an add-on it can usually be twice daily.
Can I use Alphagan P Drop with my child?
If your child is under 2 years old, do not use Alphagan P Drop — it can cause life-threatening apnoea. For children 2–6 years, use only under specialist supervision. Children over 6 are generally treated like adults but with closer monitoring for somnolence.
What is Purite preservative?
An oxidising preservative that breaks down on contact with the tear film into water, oxygen, and chloride ions. Gentler than benzalkonium chloride for long-term daily use.
Why does Alphagan P Drop make me feel tired?
Brimonidine crosses the blood-brain barrier and activates central alpha-2 receptors (similar to clonidine), causing sedation, dry mouth, and mild hypotension. Use punctal occlusion to reduce systemic absorption.
Can I combine Alphagan P Drop with other glaucoma drops?
Yes — additive with prostaglandins, beta-blockers, and CAIs. Wait 5 minutes between bottles. Fixed combinations such as brimonidine+timolol exist.
What if I take MAO inhibitors?
Avoid the combination — additive sedation and hypotension are possible. Discuss with your prescriber.
Can I drive after using Alphagan P Drop?
Brimonidine can cause drowsiness, especially when starting or in heat. Wait until you know how it affects you before driving long distances.
Mi a teendő, ha kihagyok egy adagot?
Take it as soon as you remember unless the next scheduled dose is close. Do not double up.
Egyéb Szemápoló Gyógyszerek
Az ezt a terméket megtekintő vásárlók ezeket az alternatívákat is figyelembe veszik kínálatunkban: Szemápolás választék:
- Xalatan szemcsepp (latanoproszt)
- Azopt szemcsepp (brinzolamid)
- Alphagan P szemcsepp (brimondin)
- Iotim szemcsepp (timolol)
- Careprost (bimatoproszt)
Orvosi felelősségi nyilatkozat
Az oldalon található információk csak tájékoztató jellegűek, és nem helyettesítik a szakorvos (szemorvos vagy optometrista) által adott orvosi tanácsot. A szemproblémák gyorsan fenyegethetik a látást – hirtelen látásvesztés, súlyos fájdalom vagy trauma esetén sürgősen forduljon szemorvoshoz. Mindig konzultáljon szakorvossal bármilyen kezelés megkezdése, leállítása vagy módosítása előtt.



























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