Seroflo Multihaler
✅ Long-term asthma control
✅ Reduces airway inflammation
✅ Relieves bronchospasm
✅ Improves lung function
✅ Prevents asthma symptoms
Seroflo Multihaler contains Salmeterol and Fluticasone Propionate.
✓ Orvosi ellenőrzés Morgan Ellis — Gyógyszerkutató · 8 év tapasztalat · Utolsó felülvizsgálat: 2026 május
⚡ Quick Answer — What is Seroflo Multihaler?
Seroflo Multihaler egy combination preventer (controller) inhaler for asthma and COPD, containing fluticasone propionate (an inhaled corticosteroid that reduces airway inflammation) plus Szalmeterol (a long-acting β2 agonist that holds the airways open for 12 hours). Each dose delivers fluticasone 100/250 mcg + salmeterol 50 mcg per dose, 10 ml-es üvegben forgalmazott. A szuszpenziós forma lehetővé teszi a pontos testsúlyalapú adagolást még a tablettát nem tudó gyermekeknél is, valamint hasznos felnőtteknél is nyelési nehézségek esetén. Cipla at WHO-GMP certified facilities — the same active drugs as international brand Seretide Multidose. Seroflo Multihaler is taken twice daily, every day, even when symptoms are absent. It is a preventer, not a rescue inhaler — keep a SABA reliever (Asthalin, Levolin) for acute attacks. Rinse mouth and gargle after every dose to prevent oral thrush and hoarseness.
📦 Minden rendelést fedez a Újraküldési Garancia — ha a csomagod nem érkezik meg 20 munkanapon belül, újraküldjük.
Miért rendelj a MedsBase-ról
Generikus gyógyszereink WHO-GMP minősítésű gyártóktól származnak, és diszkrét, egyszerű csomagolásban szállítjuk őket világszerte — a csomagon nem szerepel a gyógyszer neve. A kártyás fizetések egy szabályozott feldolgozón keresztül történnek (a számlaleírások egy szabályozott kártyafizetési feldolgozót tartalmaznak — soha nem “MedsBase” vagy bármilyen gyógyszer neve). Kriptovalutát és SEPA banki átutalást is elfogadunk. Minden rendelést a Reshipment Assurance Policy biztosíték fedez.
What Is Seroflo Multihaler?
Seroflo Multihaler is an Indian-manufactured dry-powder multihaler kombinálja fluticasone propionate + Szalmeterol. The international brand of this combination is Seretide Multidose. Combination ICS-LABA inhalers deliver superior asthma and COPD control compared to either component alone, with a single device improving adherence and reducing the risk of using LABA monotherapy (which carries a black-box warning for asthma death without concomitant ICS).
How Does Seroflo Multihaler Work?
The two active ingredients work on different mechanisms in parallel:
- fluticasone propionate (inhaled corticosteroid): suppresses inflammatory cytokines, reduces eosinophil and lymphocyte infiltration, stabilises airway mucosa, restores β2 receptor responsiveness. Effect builds over 1–2 weeks of consistent dosing.
- Szalmeterol (long-acting β2 agonist): activates bronchial smooth muscle β2 receptors, raising cyclic AMP and producing sustained bronchodilation lasting 12 hours (formoterol has 1–3 minute onset; salmeterol 15–30 minute onset).
- Synergy: the corticosteroid restores β2 receptor expression and prevents tachyphylaxis to LABA; the LABA improves smooth-muscle relaxation that ICS alone does not address. Combined, they reduce exacerbations more than either component alone at equivalent doses.
Felhasználás és indikációk
- Persistent asthma not controlled by ICS alone — first-line ICS-LABA combination
- Asthma maintenance therapy — twice daily, every day, regardless of symptoms
- COPD with frequent exacerbations, especially with elevated blood eosinophil count (≥300/µL) or asthma overlap
- Asthma-COPD overlap syndrome (ACOS)
- Step-up from ICS monotherapy when symptoms or exacerbations persist
Seroflo Multihaler Dosage
| Betegek | Dose | Gyakoriság |
|---|---|---|
| Adults — moderate | 1 inhalation 100/50 | Twice daily |
| Adults — severe | 1 inhalation 250/50 | Twice daily |
| Adults — COPD | 1 inhalation 250/50 | Twice daily |
How to Use Seroflo Multihaler Properly
- Hold the Multihaler upright. Slide the cover down to load a dose.
- Listen for the click — confirms dose readiness.
- Kilégzés teljesen, az eszköztől távol.
- Fogja össze az ajkait a szájrész körül.
- Inhale forcefully and deeply.
- Remove, hold breath 10 seconds, breathe out gently.
- Slide the cover up to close.
- Rinse mouth and spit; check the dose counter.
Side Effects of Seroflo Multihaler
Common (mostly local from ICS, plus some β2 effects from LABA):
- Oral thrush (white candidal plaques in mouth or throat)
- Hoarse voice / dysphonia
- Mild tremor (LABA effect; less than with high-dose SABA)
- Palpitations or heart rate increase (≤10 bpm at standard dose)
- Fejfájás
- Throat irritation, mild cough on inhalation
Kevesebb gyakorisággal:
- Enyhe növekedési sebesség csökkenés gyermekeknél magas dózisokban
- Easy bruising at high cumulative ICS doses
- Hypokalaemia at high LABA doses (with diuretics, theophylline, oral steroids)
- Pneumonia in COPD users (slight ICS-related increase)
- Adrenal suppression with high doses or strong CYP3A4 inhibitor co-prescription
Serious (stop and seek emergency help):
- Severe allergic reaction / anaphylaxis
- Paradox bronchospasmus
- Severe palpitations, chest pain, irregular heartbeat
- Adrenal crisis during illness or surgery
Figyelmeztetések és elővigyázatosság
- Use every day, even when you feel well. The benefit accumulates over 1–2 weeks; symptoms return within days of stopping.
- Never use the LABA component alone in asthma — LABA without ICS carries a higher risk of severe asthma death. {$brand} contains both components, so this is not an issue with this product.
- {$brand} is not a rescue inhaler (use Asthalin or Levolin for acute attacks).
- Rinse mouth, gargle, and spit out after every dose; brush teeth before bed.
- COPD users: ICS slightly raises pneumonia risk — ensure ICS adds value (eosinophilic phenotype, frequent exacerbations).
- Erős CYP3A4 gátlók (ritonavir, ketoconazole, itraconazole, clarithromycin) raise systemic exposure of both components — avoid prolonged co-prescription.
- Terhesség és szoptatás: Budesonide-formoterol has the most pregnancy data; uncontrolled asthma is far more dangerous than the medication.
- Szív- és érrendszeri betegség: use cautiously in severe coronary artery disease, arrhythmias, hyperthyroidism, severe heart failure.
Ellenjavallatok
- Known hypersensitivity to fluticasone propionate, salmeterol, or any formulation excipient
- Untreated active fungal, bacterial, mycobacterial (TB), or viral respiratory infection
- Severe hypersensitivity to lactose or milk proteins (DPI formulations contain lactose)
- Acute asthma attack — use a SABA reliever instead
Gyógyszerkölcsönhatások
| Interakcióba lépő gyógyszer | Hatás | Teendők |
|---|---|---|
| Strong CYP3A4 inhibitors (ritonavir, ketoconazole, itraconazole, clarithromycin) | Raise systemic ICS exposure → adrenal suppression / Cushing risk | Avoid; monitor cortisol if essential |
| Nem szelektív béta-blokkolók (propranolol, timolol cseppek) | Block LABA effect — risk of severe bronchospasm | Avoid; switch to cardioselective if essential |
| Hurok- vagy tiazid-diuretikumok | Additive hypokalaemia from LABA | Monitor potassium with high doses |
| Theophylline / aminophylline | Additív tachycardia és hypokalaemia | Szívfrekvencia és kálium monitorozása |
| MAO-k és triciklusos antidepresszánsok | Potentiate LABA cardiovascular effects | Óvatosan — vérnyomás/szívfrekvencia monitorozása |
Tárolás
- Tárolás 25°C alatt 25°C in a dry place. Keep desiccant in the bottle.
- Do not store in the bathroom — humidity makes the powder clump and reduces dose delivery.
- Once the strip/blister is opened, use within the period stated on the leaflet (typically 2–3 months).
- Tartsa gyermekektől elérhetetlen helyen.
Kapcsolódó alternatívák a MedsBase-en
- Budecort Inhaler — budesonide tartalmú megelőző inhalációs szteroid
- Asthalin Inhaler — salbutamol gyorshatású hörgőtágító
- Tiova Inhaler — tiotropium tartalmú hosszú hatású muszkarinreceptor-antagonista COPD kezelésére
- Montair — montelukast LTRA add-on
- Duolin Inhaler — salbutamol + ipratropium combo reliever
Gyakran Ismételt Kérdések
Is Seroflo the same as Seretide or Advair?
Yes — all three contain fluticasone propionate + salmeterol. Seretide (GSK, EU/UK), Advair (GSK, US), Seroflo (Cipla, India). Clinically interchangeable at equivalent strength pairs.
Why is Seroflo a preventer and not a rescue inhaler?
The salmeterol component has slow onset (15–30 minutes) — it does not relieve acute breathlessness. For acute attacks, use a separate SABA reliever (Asthalin, Levolin). Take Seroflo every day to prevent attacks.
How long until Seroflo starts to work?
Some lung function gain by day 1; symptom improvement by week 1; full preventer effect by 2–4 weeks of consistent twice-daily use.
Why must I rinse my mouth after Seroflo?
Local steroid deposition can cause oral thrush and hoarseness. Rinsing, gargling, and spitting after every dose largely prevents both.
Can children use Seroflo?
Yes from age 4 — typically at 50/25 or 100/25 strength via inhaler with spacer + mask. Higher strengths reserved for older children and adults.
Is Seroflo safe in pregnancy?
Fluticasone has reassuring observational data in pregnancy. Budesonide-formoterol (Foracort) has more data; some prescribers prefer that combination during pregnancy. Uncontrolled asthma is more dangerous than either drug.
Can I use Seroflo as a SMART/MART reliever?
No — salmeterol has slow onset and is not licensed for as-needed use. Only formoterol-containing combinations (Foracort, Symbicort) can be used as SMART/MART.
How long does a Seroflo Inhaler last?
A 120-actuation canister lasts 60 days at twice-daily dosing. Rotacaps come in blister packs; check the leaflet for actuations per pack.
What’s the difference between Seroflo Inhaler, Rotacaps, Multihaler, Autohaler, Accuhaler?
All deliver fluticasone + salmeterol but use different devices and dose strengths. Inhaler = pressurised aerosol with spacer-friendly dosing. Rotacaps = single-dose dry powder via Rotahaler. Multihaler = multi-dose dry powder. Autohaler = breath-activated MDI (no need to coordinate). Accuhaler = multi-dose blister-strip dry powder. Choose based on your inspiratory ability and coordination.
Kapcsolódó alternatívák
Egyéb termékek a Krónikus betegségek vásárlók által szintén megtekintett termékek:
További lehetőségek az asztma/COPD kezelésében
Rangsorolva a MedsBase legutóbbi rendelési adatai alapján — hogy ebben a kategóriában más vásárlók mit választanak.
| Erősség | 50+500 mcg |
|---|---|
| Mennyiség | 1 Inhaler/s, 2 Inhaler/s, 3 Inhaler/s, 6 Inhaler/s |
Seroflo Multihaler
Kérdések és válaszok
Seroflo Multihaler
Kapcsolódó termékek
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