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Revolade

Revolade (Eltrombopag 25/50 mg) — GSK thrombopoietin receptor agonist for chronic ITP, severe aplastic anaemia, hepatitis C-associated thrombocytopenia.

Artikelnummer: Revolade Categories: , ,

Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience  · Last reviewed: May 2026

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Quick Answer

Revolade — Eltrombopag 25/50 mg (GlaxoSmithKline). Thrombopoietin receptor agonist for chronic immune thrombocytopenia (ITP), severe aplastic anaemia, hepatitis C-associated thrombocytopenia, chemotherapy-induced thrombocytopenia.

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⚠️ Specialist-supervised cancer therapy — this medication is started, monitored, and stopped by an oncologist or haematologist. Dosing depends on tumour type, stage, body surface area, organ function, and concomitant therapy. Self-treatment is not appropriate; the information below is educational and supports informed conversations with your specialist.

Hepatotoxicity + thromboembolic risk
FDA black-box warning for hepatotoxicity. Baseline + biweekly LFTs, then monthly. Stop if ALT >3× ULN with symptoms. Risk of thrombotic events — avoid dose-related platelet rises >200,000/μL. Take on empty stomach away from polyvalent cations (calcium, iron, magnesium — separate by 4 hours).

Frequently Asked Questions

When is this used?

Thrombopoietin receptor agonist for chronic immune thrombocytopenia (ITP), severe aplastic anaemia, hepatitis C-associated thrombocytopenia, chemotherapy-induced thrombocytopenia.

Side effects?

Class-specific — see safety boxes above. Most supportive cancer medications are well-tolerated when used per protocol but require specialist supervision.

Drug interactions?

Always disclose all medications. Cancer supportive therapy interacts with multiple cytotoxics, chemo regimens, and concomitant medications.

Pregnancy?

Variable by molecule. Consult oncology for pregnancy planning during cancer therapy.

Monitoring?

Specialist-determined — typically FBC, electrolytes, renal/liver function, cardiac monitoring as relevant.

What if I miss a dose?

Take when you remember; do not double up. Discuss with oncology team if multiple doses missed.

When is treatment finished?

Determined by clinical response, planned regimen length, and patient tolerance.

Storage?

Per package insert — typically below 25-30°C, away from light and moisture. Pregnant household members should not handle broken tablets/capsules.

Cost?

Generic Indian biosimilars and chemical equivalents are dramatically less expensive than originator products with documented bioequivalence and clinical equivalence.

Vaccines?

Coordinate with oncology — live vaccines may be contraindicated during cancer therapy.

Other Cancer & Supportive Medications

  • Xeloda — capecitabine 500 mg — oral 5-FU prodrug for breast/colorectal/gastric cancers
  • Altraz — anastrozole 1 mg — aromatase inhibitor for post-menopausal breast cancer
  • Xbira — abiraterone 250 mg — CYP17 inhibitor for metastatic prostate cancer
  • Zoldria — zoledronic acid IV — for bone metastases and hypercalcaemia
  • Actorise — darbepoetin alfa — for chemotherapy-induced anaemia
Medical Disclaimer: Cancer therapy is highly individualised. Specific drug, dose, schedule, monitoring, and supportive care must be determined by a qualified oncologist or haematologist based on tumour biology, staging, comorbidities, and goals of care. This information is educational; it does not substitute for professional medical advice.

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Strength

25 mg, 50 mg

Quantity

14 Tablet/s, 28 Tablet/s, 56 Tablet/s

Pharma Form

Tablet/s

Manufacturer

Glaxosmithkline

Treatment

Low platelet count due to ITP or HCV infection

Generic Brand

Eltrombopag

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