Xepar

✅ Treats depression
✅ Manages anxiety disorders
✅ Javítja a hangulatot
✅ Enhances well-being
✅ Regulates serotonin levels

Xepar contains Paroxetine.

SKU: N/A Kategória: Kategória áttekintése, Krónikus betegségek, Helyzeti szorongás kezelése Címke: Paroxetin, Xepar

✓ Orvosi ellenőrzés Morgan Ellis — Gyógyszerkutató · 8 év tapasztalat · Utolsó felülvizsgálat: 2026 május

Több vásárlás, több megtakarítás Ár tablettánként

Válasszon erősséget a csomagárak megtekintéséhez.

Titkosított fizetés

Kriptovaluta fizetés 10% kedvezmény

Diszkrét világszerte szállítás

1 400+ vásárló · 50+ ország

Erősség

10 mg
20 mg
30 mg
40 mg

Mennyiség

30 tabletta
60 Tablet/s
90 tabletta
180 tabletta

Törlés

⚡ Quick Answer — What is Xepar?

Xepar tartalmaz paroxetine 20 mg from a WHO-GMP certified manufacturer (Sun Pharma) — the SSRI with the broadest range of FDA-approved anxiety indications (MDD, GAD, social anxiety, panic, OCD, PTSD, PMDD). Standard adult dose: 20 mg once daily in the morning with food (range 10–50 mg/day). Of all SSRIs, paroxetine has the strongest discontinuation syndrome (very short half-life, no active metabolite) — tapering is mandatory; patients should never stop abruptly. Pregnancy category D — not used in pregnancy due to first-trimester cardiac defect signal. Most weight gain and sexual dysfunction of the common SSRIs. Strong CYP2D6 inhibitor — major interactions with metoprolol, codeine, tamoxifen.

Mit kapsz a MedsBase-nál: WHO-GMP minősítésű gyártó · Diszkrét csomagolás · Világszerte szállítás · 1.400+ hitelesített vásárlói vélemény

📦 Minden rendelést fedez a Újraküldési Garancia — ha a csomagod nem érkezik meg 20 munkanapon belül, újraküldjük.

Miért rendelj a MedsBase-ról

Generikus gyógyszereink WHO-GMP minősítésű gyártóktól származnak, és diszkrét, egyszerű csomagolásban szállítjuk őket világszerte — a csomagon nem szerepel a gyógyszer neve. A kártyás fizetések egy szabályozott feldolgozón keresztül történnek (a számlaleírások egy szabályozott kártyafizetési feldolgozót tartalmaznak — soha nem “MedsBase” vagy bármilyen gyógyszer neve). Kriptovalutát és SEPA banki átutalást is elfogadunk. Minden rendelést a Reshipment Assurance Policy biztosíték fedez.

Important — this is not a situational-anxiety medication. Xepar is a szerotonin visszavétel-gátló (SSRI), prescribed and titrated over weeks for major depressive disorder (MDD), generalised anxiety disorder (GAD), social anxiety, panic disorder, OCD, PTSD, and PMDD. It is nem the right drug for acute, performance-related anxiety (flying, public speaking, exams) — for those use cases beta-blockers (propranolol), benzodiazepines, or hydroxyzine are clinically appropriate. If you do not have a diagnosed mood, anxiety, or psychiatric disorder, do not start this medication.

FDA black-box warning — suicidality. All antidepressants carry an FDA black-box warning for increased risk of suicidal thinking and behaviour in children, adolescents, and young adults under 25, particularly during the first weeks of treatment or after dose changes. Family members and prescribers should monitor closely for worsening mood, agitation, or suicidal ideation in this age group.

What Is Xepar?

Xepar is an oral tablet of paroxetine hydrochloride 20 mg manufactured by Sun Pharma. Paroxetine (US brand Paxil; UK brand Seroxat) is an SSRI launched by SmithKline Beecham in 1992 and one of the most-prescribed antidepressants in the 1990s and early 2000s. It potently and selectively blocks the serotonin transporter (SERT) and has the broadest range of FDA-approved indications across the SSRI class.

Jóváhagyott indikációk

Súlyos depressziós zavar (MDD)
Generalised anxiety disorder (GAD)
Social anxiety disorder (chronic / generalised)
Pánikzavar — with and without agoraphobia
Kényszerbetegség (OCD)
Poszttraumás stressz zavar (PTSD)
Premenstruális diszfórás zavar (PMDD)
Off-label: hot flashes (low-dose 7.5 mg paroxetine mesylate is FDA-approved for this; off-label for menopause vasomotor symptoms in women who cannot use HRT)

Adagolás

Agoprex is a 25 mg agomelatine tablet supplied by Sun Pharma. Agomelatine is mechanistically unique among antidepressants: it acts as an agonist at melatonin MT1 and MT2 receptors and an antagonist at 5-HT2C serotonin receptors. The dual mechanism resynchronises disrupted circadian rhythms (a feature of major depression) while indirectly increasing dopamine and noradrenaline release in the frontal cortex.	Kezelés indítása	Indications and dosing	Megjegyzések
MDD, GAD, social anxiety, PTSD	20 mg/day in the morning with food	20–50 mg/day	Increase by 10 mg/day at intervals of at least 1 week
Pánikzavar	10 mg/day × 1 week	40–60 mg/day	Slow up-titration to avoid early panic exacerbation
OCD	20 mg/nap	40–60 mg/day	Often requires upper end of range; 8–12 weeks for assessment
PMDD	12.5–25 mg/day	25–50 mg/day	Continuous or luteal-phase only dosing
Idős / májkárosodott betegek	10 mg/day	Maximum 40 mg/day	Reduce starting dose; titrate slowly

Mellékhatások

Side-effect profile

Gyakoriság	Hatás	Megjegyzések
Gyakori	Nausea, dry mouth, constipation, sweating	Anticholinergic burden is mild but more than other SSRIs
Gyakori	Sedation	Take at bedtime if drowsy; can help if insomnia is a depressive symptom
Gyakori	Sexual dysfunction (delayed orgasm, low libido, erectile difficulty)	Highest of the SSRIs — up to 60% of long-term users
Gyakori	Weight gain (3–7+ kg over 6–12 months)	Highest of the SSRIs
Gyakori	Dizziness, blurred vision	Anticholinerg
Kevesebb gyakoriságú	Bruising, GI bleeding	Caution with NSAIDs / anticoagulants
Kevesebb gyakoriságú	Hyponatraemia (SIADH)	Older adults at risk
Ritka	Szerotonin szindróma	See interactions
Ritka	Akathisia (restless agitation), suicidal ideation	First weeks of treatment; black-box monitoring

Discontinuation Syndrome — the Paroxetine Problem

Paroxetine has the shortest half-life of all SSRIs (~21 h) és no active metabolite. This combination produces the worst discontinuation syndrome in the antidepressant class: dizziness, brain zaps, paraesthesia, anxiety, irritability, insomnia, nausea, and headache — often beginning within 24–48 hours of a missed dose. Symptoms can persist for weeks if stopped abruptly.

Mandatory taper: reduce by 10 mg every 2–4 weeks for short-term users; for long-term users (> 1 year), use much slower hyperbolic tapers (e.g. liquid formulation step-downs of 1–2 mg every 2–4 weeks below 10 mg). Never stop paroxetine abruptly outside a hospital setting.

Gyógyszerkölcsönhatások

Absolute contraindications: MAOIs, linezolid, methylene blue, thioridazine, pimozide. 14-day washout period.

CYP2D6 (strong inhibitor) — clinically meaningful: tamoxifen (reduces conversion to endoxifen — avoid in breast cancer survivors), codeine and tramadol (reduces analgesic activation), metoprolol and other 2D6 beta-blockers (raises plasma levels), atomoxetine, risperidone, aripiprazole (raises levels).

Serotonergic interactions: triptans, tramadol, dextromethorphan, St John’s wort, lithium — serotonin syndrome risk.

Anticoagulants and NSAIDs: increased bleeding risk (especially upper GI).

Terhesség és szoptatás

Pregnancy category D — first-trimester paroxetine exposure has been associated with a small but reproducible signal for fetal cardiac malformations, particularly Ebstein’s anomaly. Paroxetine is not used in pregnancy when alternatives (sertraline, citalopram, escitalopram) are available. Women planning pregnancy should switch antidepressants well in advance.

Breastfeeding: low transfer; sertraline is preferred but paroxetine is reasonable if continuing what worked in pregnancy.

Gyakran Ismételt Kérdések

How long does Xepar take to work?

Anxiety and panic symptoms often respond within 2–3 weeks; mood response in MDD typically appears at 4–6 weeks. OCD may require 8–12 weeks at higher doses.

Why is paroxetine harder to come off than other SSRIs?

Paroxetine has a very short half-life (about 21 hours) and no active metabolite, so plasma levels drop fast when doses are missed. This produces a sharper withdrawal than longer-half-life SSRIs (sertraline, citalopram) or those with active metabolites (fluoxetine).

Can I switch from Xepar to another SSRI?

Yes — common switch destinations are sertraline (cleaner profile) or escitalopram (better tolerated). Switches usually involve cross-tapering or a paroxetine taper followed by a brief washout. Always done under prescriber direction.

Is Xepar safe in pregnancy?

Paroxetine is generally avoided in pregnancy due to a small first-trimester cardiac defect signal. Women planning pregnancy should switch to sertraline or escitalopram in advance.

Will Xepar cause weight gain?

Yes — paroxetine causes the most weight gain of the SSRIs (commonly 3–7 kg over 6–12 months). This is a significant reason patients switch to sertraline, escitalopram, or bupropion.

Does paroxetine help with menopause hot flashes?

Low-dose paroxetine (7.5 mg paroxetine mesylate, sold as Brisdelle in the US) is FDA-approved for menopausal hot flashes — useful for women who cannot or prefer not to use hormone replacement.

Mi történik, ha kihagyok egy adagot?

Take it as soon as you remember; if you remember close to the next dose, skip the missed one. Do not double up. Missing more than one dose can produce noticeable withdrawal symptoms within 24–48 hours.

Can Xepar be combined with anti-anxiety medication?

In severe panic disorder, prescribers sometimes overlap a benzodiazepine for the first 2–4 weeks until the SSRI takes effect, then taper the benzodiazepine. This is a short-term bridging strategy, not chronic combination therapy.

How is Xepar different from sertraline?

Both are SSRIs with similar mechanism. Paroxetine has more sedation, more weight gain, more sexual dysfunction, worse discontinuation, and a stronger CYP2D6 interaction profile — but historically a marginally faster anxiety response. Sertraline is the cleaner first choice for most patients.

How should Xepar be stored?

Store at 15–30 °C in the original blister packaging, away from moisture and sunlight. Keep out of reach of children.

Orvosi felelősségi nyilatkozat: Information on this page is intended for adults using prescribed psychiatric medication and is not a substitute for individualised medical care. Antidepressants, antipsychotics, and related medications can interact with other drugs, alcohol, and pre-existing conditions. Discuss any new medication, dose change, or planned discontinuation with a qualified prescriber. If you experience suicidal thoughts, mania, severe akathisia, signs of serotonin syndrome (high fever, confusion, muscle rigidity, rapid heart rate), or neuroleptic malignant syndrome, seek emergency care immediately.