Quick Answer
Quadriderm RF Cream — Beclomethasone dipropionate 0.025% + clotrimazole 1% + neomycin 0.5% + tolnaftate 1% (Fulford). Quadruple-action topical for mixed inflammatory + bacterial + fungal skin infections — short-term symptomatic use only, NOT first-line single-pathogen therapy.
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Quadriderm RF Cream ships from a WHO-GMP certified manufacturer in plain packaging, billed through a regulated payment processor (the statement descriptor reads a regulated card-payment processor — never MedsBase or any medication name). Every order carries our 20-business-day Reshipment Assurance.
Combination steroid-antimicrobial creams have a high misuse risk: prolonged use causes skin atrophy, telangiectasia, striae, perioral dermatitis, and topical steroid withdrawal. Use only when a mixed bacterial+fungal+inflammatory picture is confirmed — single-pathogen rashes are better treated with the corresponding single-agent therapy. Maximum 1-2 weeks; reassess if no improvement.
How to use
Apply a thin layer to affected area twice daily. Wash hands afterwards (unless treating the hands). Stop and reassess at 2 weeks if no improvement, or sooner if symptoms worsen.
Avoid these areas without specialist advice:
- Face — high risk of perioral dermatitis, steroid rosacea
- Genitals/groin — atrophy, striae, hypopigmentation
- Skin folds (axilla, under breasts) — occluded steroid effect, candida overgrowth despite the antifungal component
- Children <12 — systemic absorption risk; lower-potency steroid alternatives preferred
- Open broken skin — risk of systemic absorption + neomycin sensitisation
5-10% of users develop neomycin contact sensitisation. Once sensitised, all topical neomycin / framycetin / paromomycin become unusable for life. If a patch worsens or a new red itchy patch appears under the cream, suspect contact allergy and stop immediately.
Întrebări frecvente
What does each ingredient do?
Beclomethasone (mid-potency steroid) reduces inflammation and itching. Clotrimazole (imidazole antifungal) treats Candida, dermatophytes, and pityriasis. Neomycin (aminoglycoside) covers Gram-negative and some Gram-positive bacteria. Tolnaftate (thiocarbamate antifungal) treats dermatophyte infections.
When is this combination really needed?
Genuine mixed dermatoses where bacterial superinfection + tinea + inflammation coexist (e.g. infected eczema with secondary tinea). For pure tinea, a single-agent antifungal is better. For pure bacterial impetigo, mupirocin is better. For pure inflammatory eczema, a steroid alone is better.
Why not use it long-term?
The steroid component causes irreversible skin atrophy, telangiectasia, and topical steroid withdrawal with prolonged use. The neomycin component causes contact sensitisation in 5-10% of users — and that allergy then complicates future antibiotic-cream use.
Will it cure athlete’s foot?
It will reduce inflammation and may help, but the steroid mask can let resistant fungal cases progress unchecked. For pure tinea pedis, single-agent topical terbinafine 1 cream (1 week) or clotrimazole 1% (2-4 weeks) is preferred.
Can I use it on a fungal nail infection?
No — topical creams do not penetrate nail plate. For onychomycosis, oral terbinafine or itraconazole is required, with topical amorolfine or ciclopirox lacquer as adjuncts.
Pregnancy & breastfeeding?
Limited safety data on the combination. Single-agent topical clotrimazole or single-agent low-potency hydrocortisone are preferred when antifungal or anti-inflammatory action is needed in pregnancy.
Children?
Avoid in children <12 unless specialist-advised. Lower-potency single-agent products are preferred.
Allergic reaction?
Discontinue immediately. Neomycin is a common topical allergen — burning, redness, or worsening rash beyond expected baseline can indicate contact dermatitis from neomycin.
Storage?
Below 30°C, away from direct sunlight. Tighten cap after use.
What if symptoms worsen?
Stop the cream and seek medical review. Worsening on a steroid-containing combination can indicate scabies, herpes simplex (which steroids worsen dramatically), or a misdiagnosed condition.
Other Skin & Topical Medications
- Candid B Lotion — clotrimazole + beclomethasone — 2-agent alternative without antibiotics
- Betnovate GM — betamethasone + gentamicin + miconazole triple
- Fucibet — fusidic acid + betamethasone — bacterial-eczema specific
- Clocip Cream — clotrimazole 1% — pure antifungal
- Tenovate Cream — clobetasol propionate — high-potency steroid alone




























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