💡 Quick Answer — What is Retino AC Gel?
Retino AC Gel contains clindamycin phosphate 1% + tretinoin 0.025% — a topical combination of an antibiotic and a retinoid for moderate-to-severe inflammatory acne vulgaris. Apply a thin layer once daily at night to clean dry skin. Avoid eyes, lips, and corners of the nose. SPF 30+ daily. Combination therapy is more effective than either agent alone but more irritating; introduce gradually.
📦 Fiecare comandă este acoperită de politica noastră de Politica noastră de Reexpediere Garantată — dacă coletul dumneavoastră nu sosește în 20 de zile lucrătoare, îl relivrăm.
De ce să comanzi de la MedsBase
Medicamentele noastre generice sunt procurate de la producători certificați WHO-GMP și expediate la nivel mondial în ambalaje discrete și simple — fără denumirea medicamentului pe exteriorul coletului. Plățile cu cardul sunt procesate printr-un procesor reglementat (descrierile de pe extrasul de cont includ un procesor de plăți cu card reglementat — niciodată “MedsBase” sau numele vreunui medicament). Acceptăm și criptomonede și transferuri bancare SEPA. Fiecare comandă este susținută de Politica noastră de Asigurare pentru Relivrare.
De ce să comanzi de la MedsBase
Choosing Retino AC Gel from MedsBase:
- producător certificat WHO-GMP — sourced from a regulated facility, finished pack with batch number and expiry.
- Ambalaj discret — plain envelope, no medication name on the outside.
- Livrare în toată lumea cu Reshipment Assurance — if your parcel does not arrive within 20 business days we re-ship at no cost (subject to policy terms).
- Loyalty points — 1 point per $1 spent (excludes peptides); 100 points = $5 off.
What Retino AC Gel is and how it works
Retino AC Gel contains clindamycin phosphate 1% + tretinoin 0.025%. Clindamycin is a lincosamide antibiotic that targets Cutibacterium acnes (formerly P. acnes) by binding the bacterial 50S ribosome and blocking protein synthesis. Tretinoin is a retinoid that normalises follicular keratinisation, reduces sebum, and accelerates comedone clearance. Combining the two gives faster and more complete clearance of inflammatory acne lesions than either agent alone, while the steric configuration of the gel formulation prevents tretinoin from oxidising the clindamycin. Manufacturer: Johnson & Johnson / Janssen (WHO-GMP certified).
Indicații
- Moderate-to-severe inflammatory acne vulgaris — papules, pustules, and nodules with comedonal background.
- Mixed comedonal-inflammatory acne where the dual mechanism shortens treatment time.
Cum să aplicați
- Cleanse with a gentle non-foaming cleanser; pat dry; wait 10–15 minutes (apply on damp skin amplifies irritation).
- Apply a pea-sized amount once daily at night to entire affected area, not just spots.
- Acclimation: alternate nights for 2 weeks if irritation is significant.
- Avoid eyes, lips, mouth corners, and nasal corners (>5 mm clearance).
- Mandatory SPF 30+ broad-spectrum daily.
- Continue for at least 8–12 weeks before judging response.
✓ Antibiotic stewardship — Topical clindamycin monotherapy drives C. acnes resistance. Combination with tretinoin (or with benzoyl peroxide) reduces resistance development. Limit clindamycin courses to 12 weeks where possible; switch to non-antibiotic maintenance (tretinoin alone, adapalene, BPO) after acne control is established.
Efecte secundare
- Frecvente: dryness, peeling, mild burning, transient acne flare in weeks 2–4 (purge), photosensitivity.
- Mai puțin frecvente: contact dermatitis, perioral dermatitis if applied close to mouth, mild gastrointestinal upset (rare from topical absorption).
- Rare: pseudomembranous colitis from systemic clindamycin absorption (very rare with topical use), severe contact allergy.
Contraindicații
- Pregnancy (Category C/X for tretinoin component) and breastfeeding.
- History of inflammatory bowel disease (clindamycin contraindication).
- Eczema, severe sunburn, broken skin at application site.
- Known hypersensitivity to clindamycin, lincosamides, or retinoids.
Interacțiuni medicamentoase
Avoid concurrent strong topical agents (BPO at the same application — apply at separate times of day; salicylic acid; alpha hydroxy acids). Topical clindamycin has additive risk if combined with neuromuscular blockers (theoretical, with significant systemic absorption only). Avoid concurrent erythromycin (cross-resistance and antagonism in some strains).
Depozitare
Store below 25 °C, away from direct light. Keep tube tightly closed.
Întrebări frecvente
Cât durează până văd rezultate?
Inflammatory lesions typically reduce by 30–50% at 4–6 weeks, with full effect by 12 weeks. If no improvement at 12 weeks, escalate to oral antibiotics, oral isotretinoin (severe cases), or hormonal therapy under specialist guidance.
Why does Retino AC Gel include both an antibiotic and a retinoid?
The two attack different parts of the acne pathway — clindamycin kills C. acnes bacteria in pores; tretinoin normalises pore-blocking dead skin and reduces sebum. The combination is more effective than monotherapy, and the retinoid component reduces antibiotic resistance development.
Is Retino AC Gel safe in pregnancy?
No — the tretinoin component is teratogenic (Category C/X). Use effective contraception throughout treatment; stop before conception.
Can I use Retino AC Gel with benzoyl peroxide?
Yes, at separate times — BPO in the morning, Retino AC Gel at night. BPO further reduces antibiotic resistance and treats inflammatory lesions independently.
Why is my skin getting worse after 2 weeks?
Retinoid purge — pre-existing micro-comedones surfacing as visible lesions. Resolves by week 4–6 with continued use. Add a non-comedogenic moisturiser; do not stop unless severe.
Can I shave the affected area?
Yes, but use a sharp blade with mild shaving cream and rinse with cool water. Allow tretinoin to fully absorb (2 hours) before shaving. Stop tretinoin 24 hours before any waxing.
Can I use Retino AC Gel on the chest and back?
Yes — if your acne involves trunk, use a thin layer; this is sometimes called “chest and back” or “torso” acne and the same protocol applies.
Is it normal for my skin to feel waxy/sticky?
A slight residue is normal in the first hour after application and absorbs fully by morning. If persistent, you may be applying too much — reduce to a smaller pea-sized amount.
Should I use Retino AC Gel if I have only mild comedonal acne?
Probably not — for purely comedonal acne (blackheads/whiteheads only, no inflammation), topical retinoid alone (Retino-A, A-Ret, Tretin) is preferred to avoid unnecessary antibiotic exposure.
How does it compare with topical adapalene + BPO?
Adapalene + BPO is a non-antibiotic alternative with similar efficacy and lower resistance risk; it is now first-line for inflammatory acne in most guidelines. Retino AC Gel is reserved when adapalene is unavailable or BPO is poorly tolerated.
Other Beauty & Skin Care Medications
- Melalite Forte Cream — hydroquinone 4% for melasma
- Retino-A Cream — tretinoin for acne and ageing
- Melacare Cream — Kligman triple for melasma
- Permite Cream — permethrin 5% for scabies
- Tenovate Cream — clobetasol 0.05% for severe inflammation
Notă medicală. This content is for general information about the product and is not medical advice or a substitute for advice from a qualified healthcare professional. Use any topical or oral medication only under appropriate medical supervision; misuse can cause serious harm.
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