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Airz

✅ Allergy symptom relief
✅ Non-drowsy formula
✅ Rapid symptom control
✅ Improved comfort

Contains Glycopyrronium bromide

Medicinskt granskad av Morgan Ellis — Apoteksforskare · 8 års erfarenhet  · Senast granskad: maj 2026

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1 400+ kunder · 50+ länder

Denna produkt är för närvarande slut i lager och inte tillgänglig.

⚡ Quick Answer — What is Airz?

Airz innehåller glycopyrronium bromide, en long-acting muscarinic antagonist (LAMA) bronchodilator that blocks parasympathetic constriction of the airways for 24 hours. Airz is used as once-daily maintenance therapy i chronic obstructive pulmonary disease (COPD) — and (in some markets) as add-on therapy for difficult-to-control asthma. Each rotacaps delivers 50 mcg per rotacap, tillverkad av Glenmark Pharma at WHO-GMP certified facilities. Same active drug as international brand Seebri Breezhaler. Airz is a controller, not a reliever — keep a SABA (Asthalin, Levolin) for acute breathlessness.

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What Is Airz?

Airz is an Indian-manufactured generic of glycopyrronium bromide, a long-acting anticholinergic bronchodilator. Internationally the same drug is sold as Seebri Breezhaler. glycopyrronium bromide binds muscarinic receptors (M1 and M3) on airway smooth muscle for many hours, providing 24-hour bronchodilation with once-daily dosing. It does not cause the tremor, palpitations, or hypokalaemia of β2 agonists.

How Does Airz Work?

The parasympathetic nervous system maintains a baseline tone in bronchial smooth muscle through acetylcholine acting on M3 muscarinic receptors. In COPD this tone is the dominant reversible component of airflow obstruction. glycopyrronium bromide is a kinetically-selective M3 antagonist — it binds and dissociates slowly, giving sustained bronchodilation over 24 hours. The result is:

  • Sustained bronchodilation for 24 hours from a single dose
  • Reduced exacerbations in COPD by 14–28% in landmark trials (UPLIFT, POET-COPD)
  • Improved exercise tolerance and reduced dyspnoea in stable COPD
  • Reduced rescue inhaler use when added to ICS-LABA in severe asthma (TIOSPIR-asthma trial)

Användningsområden och indikationer

  • COPD maintenance — first-line LAMA at GOLD groups B, E (with or without LABA / ICS depending on phenotype)
  • COPD exacerbation prevention
  • Add-on for severe asthma not controlled by ICS-LABA (Step 5 GINA)
  • Asthma-COPD overlap (ACOS)

Airz Dosage

PatientDosFrekvens
Adults — COPD maintenance50 mcg (1 capsule)Once daily

How to Use Airz Properly

  • Insert one rotacap into the Rotahaler with the coloured end down.
  • Twist sharply — listen for the click.
  • Breathe out fully away from device.
  • Seal lips around mouthpiece.
  • Inhale forcefully and deeply; you should hear the rotacap whir.
  • Hold breath 10 seconds, then breathe out slowly.
  • Check rotacap is empty; repeat if powder remains.
  • For ICS-containing combinations: rinse mouth, gargle, and spit out.

Side Effects of Airz

Common (anticholinergic, dose-related):

  • Dry mouth (commonest — typically mild, may improve with sips of water)
  • Constipation
  • Throat irritation, mild cough on inhalation
  • Sinusitis, rhinitis, nasopharyngitis
  • Mild urinary hesitancy in older men with prostate enlargement

Mindre vanliga:

  • Acute angle-closure glaucoma (rare; care with mist contacting eyes)
  • Urinary retention in patients with prostatic obstruction
  • Tachycardia, palpitations (less common than with β2 agonists)
  • Blurred vision (transient if drug contacts eyes)
  • Atrial fibrillation in susceptible older patients

Serious (stop and seek emergency help):

  • Severe allergic reaction / anaphylaxis / angio-oedema
  • Acute eye pain with red eye, halos around lights, blurred vision (suspected glaucoma — emergency)
  • Acute urinary retention
  • Paradoxical bronchospasm

Varningar och försiktighetsåtgärder

  • {$brand} is a controller, not a reliever. Use Asthalin or Levolin for acute breathlessness.
  • Use once daily, every day — protective effect is maintained only with consistent dosing.
  • Avoid mist contacting the eyes — risk of acute angle-closure glaucoma in predisposed patients (narrow anterior chamber, family history). Seek immediate help if eye pain or vision change occurs.
  • Prostatic obstruction: use cautiously in men with benign prostatic hyperplasia or bladder neck obstruction — risk of urinary retention.
  • Renal impairment: glycopyrronium bromide is largely renally excreted; use cautiously when CrCl <50 ml/min and monitor for systemic anticholinergic effects.
  • Graviditet och amning: limited data — use only if benefit clearly outweighs risk.
  • Storage: keep capsules in the original blister with desiccant; do not pre-load multiple capsules.

Kontraindikationer

  • Known hypersensitivity to glycopyrronium bromide, atropine derivatives, or formulation excipients
  • Severe hypersensitivity to lactose or milk proteins (DPI formulations contain lactose)
  • Acute glaucoma — relative contraindication
  • Severe symptomatic prostatic obstruction or bladder outlet obstruction — relative

Läkemedelsinteraktioner

Interacting drugEffektVad man ska göra
Other anticholinergics (oral atropine, oxybutynin, hyoscine)Additive dry mouth, urinary retention, constipationMonitor symptoms — combine cautiously
Tricyclic antidepressantsAdditive anticholinergic burdenCaution in elderly
Antihistamines (1st generation)Additive anticholinergic effectsAvoid combination if possible

Förvaring

  • Store below 25°C in a dry place. Keep desiccant in the bottle.
  • Do not store in the bathroom — humidity makes the powder clump and reduces dose delivery.
  • Once the strip/blister is opened, use within the period stated on the leaflet (typically 2–3 months).
  • Keep out of reach of children.

Relaterade alternativ på MedsBase

Vanliga frågor

How is glycopyrronium different from tiotropium?

Both are LAMAs for COPD. Glycopyrronium has a faster onset (5 min for partial effect) than tiotropium (1–3 h to peak), but final 24-hour bronchodilation is similar. Glycopyrronium is also the LAMA component in some combination inhalers (Ultibro, Xoterna with indacaterol; Trimbow with formoterol + beclomethasone).

Is Airz the same as Seebri?

Yes — both deliver glycopyrronium 50 mcg per dry-powder capsule. Seebri Breezhaler (Novartis) is the international brand; Airz (Glenmark) is the Indian-market generic. Clinically interchangeable.

Can Airz be used for asthma?

Glycopyrronium is licensed for COPD only — tiotropium has more asthma data and is the LAMA of choice for severe asthma add-on. Discuss with your prescriber.

Why is Airz once daily?

Glycopyrronium has a long airway residence time (~24 h), allowing once-daily maintenance dosing.

Does Airz cause dry mouth?

Yes — the most common LAMA side effect. Usually mild; manage with sips of water, sugar-free gum, good oral hygiene.

Is Airz a rescue inhaler?

No — it is a controller. Keep a SABA (Asthalin, Levolin) for acute attacks.

Can I take Airz during pregnancy?

Limited data — use only if benefit clearly outweighs risk.

What if mist contacts my eyes?

Risk of acute angle-closure glaucoma in predisposed patients. Aim away from eyes; seek emergency care for eye pain or halos around lights.

How does Airz compare to ipratropium (Ipravent)?

Ipratropium is short-acting (4–6 hours, 4× daily). Glycopyrronium is long-acting (24 hours, once daily). Modern COPD management uses LAMAs (long-acting); short-acting ipratropium is reserved for symptomatic relief, COPD exacerbations, or asthma add-on.

Medical disclaimer: This page is educational and does not replace professional medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any inhaler or respiratory medication, especially if you have other medical conditions, take other prescriptions, are pregnant or breastfeeding, or are over 65.

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Styrka

50 mcg

Kvantitet

30 Rotacap/s, 60 Rotacap/s, 90 Rotacap/s

Pharma Form

Capsule/s

Manufacturer

Glenmark Pharma

Treatment

Chronic obstructive pulmonary disease (COPD)

Generic Brand

Glycopyrronium bromide

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