Betnovate C Cream
✅ Zmniejsza stan zapalny skóry
✅ Leczenie infekcji bakteryjnych
✅ Lightens skin tone
✅ Heals skin allergies
✅ Soothes psoriasis symptoms
Betnovate C Cream contains betamethasone valerate i clioquinol.
✓ Zweryfikowany medycznie przez Morgan Ellis — Badacz farmaceutyczny · 8 lat doświadczenia · Ostatnia weryfikacja: maj 2026
⚡ Quick Answer — What is Betnovate-C Cream?
Betnovate-C Cream zawiera betamethasone valerate 0.1% + clioquinol 3% — a fixed-dose combination of a potent topical corticosteroid (UK Class III / US Class III, “potent”) with clioquinol, a broad-spectrum antibacterial and antifungal halogenated hydroxyquinoline — manufactured by Glaxo SmithKline. Used for short-term treatment of inflamed skin conditions complicated by bacterial OR fungal infection — infected eczema, contact dermatitis with secondary infection, lichen simplex chronicus with bacterial colonisation, infected discoid eczema, otitis externa with eczematous component. Apply a thin film once or twice daily for a maximum of 7-10 days. Beyond this, the antibiotic component should be discontinued (continue plain steroid alone if needed) to avoid sensitisation, resistance, or toxicity. Ważne: Clioquinol is a halogenated hydroxyquinoline that can stain skin, hair, fabrics, and bath surfaces yellow. Wear old clothing and use dark-coloured towels during treatment. Stains can be permanent on light fabrics. Do NOT apply to the face, eyelids, armpits, groin, or genital area for more than a few days — thin-skin areas have much higher absorption with both atrophy risk from the steroid AND systemic-toxicity risk from the antibiotic.
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What Is Betnovate-C Cream?
Betnovate-C Cream is a fixed-dose topical combination cream containing betamethasone valerate 0.1% + clioquinol 3%. Glaxo SmithKline manufactures the original branded version; generic equivalents are widely available globally. Pack size at MedsBase: 30 g tube.
The rationale for combining a potent steroid with an antibacterial in one product is to address inflammatory skin conditions where bacterial colonisation or infection is contributing to the inflammation — eczematous skin in particular is prone to Staphylococcus aureus overgrowth, which perpetuates the inflammatory cycle. Treating the inflammation alone (steroid) without addressing the bacteria leads to slower clearance and higher recurrence; treating the bacteria alone (without controlling inflammation) is similarly limited.
How Betnovate-C Cream Works
- Betamethasone valerate 0.1% — binds intracellular glucocorticoid receptors in keratinocytes and inflammatory cells, suppressing pro-inflammatory cytokines (IL-1, IL-2, IL-6, TNF-α), inhibiting phospholipase A2, and promoting T-lymphocyte apoptosis. Result: rapid suppression of skin inflammation, redness, swelling, and itch.
- Clioquinol — broad-spectrum antibacterial and antifungal halogenated hydroxyquinoline targeting bacteria contributing to or complicating the dermatitis. Reduces bacterial colonisation that perpetuates the inflammatory cycle.
- Efekt kombinowany — faster clearance of infected/colonised inflammatory dermatoses than either component alone.
Onset of effect: visible improvement within 24-72 hours; full response in 1-2 weeks at the right indication.
When Betnovate-C Cream Is Used
Betnovate-C Cream is for short-term treatment of:
- Infected eczema or atopic dermatitis with visible signs of bacterial superinfection (crusting, weeping, golden-yellow exudate)
- Infected contact dermatitis
- Infected lichen planus, lichen simplex chronicus
- Infected discoid eczema
- Infected psoriasis (selected cases; usually a sign of mismanagement, e.g. excessive steroid use causing skin atrophy and infection)
- Otitis externa with an eczematous and bacterial/fungal component (selected cases)
Betnovate-C Cream is NOT indicated for routine eczema/dermatitis without infection — in those cases, plain betamethasone valerate 0.1% (without antibiotic) is the appropriate choice. Long-term use of an antibiotic-containing topical promotes bacterial resistance and systemic clioquinol absorption.
Betnovate-C Cream Dosage and How to Apply
- Wash and dry the affected area first.
- Umyj ręce before and after applying.
- Apply a thin film to the affected area — one fingertip unit (FTU = ~0.5 g) treats an area roughly two adult palms in size.
- Rub in gently until absorbed. Do NOT use thick layers.
- Once or twice daily as directed.
- Maximum continuous course: 7-10 days. After this period, the antibiotic-containing combination should be stopped. If the underlying inflammatory condition still needs treatment, continue with plain betamethasone valerate 0.1% (or another appropriate steroid) without the antibiotic.
- Do NOT cover with airtight dressings — occlusion increases systemic absorption ten-fold for both the steroid AND the antibiotic.
- Allow at least 30 minutes before applying any moisturiser to the same area.
Where NOT to Apply Betnovate-C Cream
- Face, eyelids, mucous membranes, and intertriginous folds — standard topical-steroid atrophy and absorption concerns, plus higher antibiotic absorption
- Eyes / periocular area — both the steroid (glaucoma, cataract risk) and the antibiotic (corneal toxicity) are problematic here
- Extensive body surface area — cumulative clioquinol systemic absorption
- Otic use — do not use in the ear canal unless specifically directed; clioquinol is potentially ototoxic if it reaches the middle ear through a perforated tympanic membrane
- Acne, perioral dermatitis, rosacea
- Ciąża for extended periods
Działania niepożądane
Local side effects:
- From the steroid component: skin atrophy, telangiectasia, striae, hypopigmentation, perioral dermatitis (face), steroid-acne, contact dermatitis
- From the clioquinol component: yellow staining of skin/hair/fabrics, mild irritation, contact dermatitis (rare)
- Burning, stinging, or itching at application site
Systemic side effects (rare with short courses; real risk with extensive or prolonged use):
- HPA-axis suppression from the steroid
- Clioquinol is absorbed through inflamed or broken skin; large-area or prolonged use can cause neurotoxicity (peripheral neuropathy, optic atrophy) at toxic systemic levels. Cumulative exposure over weeks should be avoided. Iodine-allergic patients should not use this combination — clioquinol contains iodine.
Przeciwwskazania i ostrzeżenia
Do not use Betnovate-C Cream if you have:
- Hypersensitivity to betamethasone, clioquinol, or any excipient (including known iodine allergy — clioquinol contains iodine)
- Untreated viral skin infection (HSV, VZV, HPV warts) or fungal infection (clioquinol has antifungal activity but the steroid component still suppresses immune control of the fungus — use a dedicated antifungal first)
- Tuberculosis of the skin, syphilitic skin lesions
- Acne vulgaris, perioral dermatitis, rosacea
- Children under 12 (Generally not used in children under 12 because of the systemic absorption / neurotoxicity profile of clioquinol. If essential, paediatric dermatology supervision required.)
- Perforated tympanic membrane (avoid otic use)
Ciąża: avoid for extended use; brief small-area use generally acceptable. Karmienie piersią: do not apply to nipple/areola.
Interakcje lekowe
- Other topical antibiotics — do not combine; redundant and increases sensitisation/resistance
- Other topical steroids — do not stack; use one at a time
- Iodine-containing medications and contrast media — clioquinol contains iodine; can interfere with thyroid function tests and is theoretically a cumulative iodine exposure.
How Betnovate-C Cream Compares to Alternatives
| Approach | When appropriate |
|---|---|
| Betnovate-C Cream (betamethasone valerate 0.1% + clioquinol 3%) | Inflamed dermatosis with infection; short courses (7-10 days) |
| Plain betamethasone valerate 0.1% | Inflammatory dermatosis without infection; longer courses possible |
| Mupirocin or fusidic acid topical | Bacterial skin infection without significant inflammation (impetigo, folliculitis) |
| Oral flucloxacillin / cephalexin | Extensive or systemic bacterial skin infection |
| Tacrolimus 0.1% / 0.03% | Steroid-sparing for thin-skin areas; long-term maintenance |
Storage & Shelf Life
Store Betnovate-C Cream below 25°C in the original tube. Replace the cap tightly after each use. Keep out of reach of children. Use within 3-6 months of first opening, or before the printed expiry date.
Najczęściej zadawane pytania
Why is Betnovate-C Cream limited to 7-10 days?
The antibiotic component (clioquinol) causes problems with prolonged use: cumulative systemic absorption with neurotoxicity risk (peripheral neuropathy, optic atrophy reported with prolonged extensive use), staining of skin/fabrics, and selection of resistant bacteria. Beyond 7-10 days, switch to plain betamethasone.
Can I use Betnovate-C Cream on my face?
No — the steroid is too potent for routine facial use, AND the antibiotic component adds extra absorption and sensitisation risks on the thin facial skin. For inflamed and infected facial dermatoses, use mild hydrocortisone separately (or topical pimecrolimus if no infection) plus a dedicated topical antibiotic course only if needed, both under doctor supervision.
My eczema is itchy but not weeping or crusted — do I need Betnovate-C Cream?
No — uncomplicated inflammatory eczema does not need an antibiotic. Plain betamethasone valerate 0.1% (or mometasone, fluticasone, etc.) is the right choice for routine flares. Reserve antibiotic-containing combinations for clearly infected or colonised dermatitis (golden crusts, weeping, classic Staph superinfection).
Why does Betnovate-C Cream stain everything yellow?
Clioquinol is a halogenated hydroxyquinoline with intrinsic yellow colour. It transfers to skin, hair, clothing, towels, and bath surfaces during application. Wear old clothing during treatment, use dark-coloured towels, and clean any porcelain or grouted surfaces immediately after they contact the cream. Stains on light fabrics may be permanent.
Is Betnovate-C Cream safe in pregnancy?
Avoid for extended use. Brief small-area use for a clear infected dermatosis may be acceptable on specialist advice. The antibiotic component crosses the placenta in small amounts; the steroid carries the same low-birth-weight concern as other potent topical steroids in pregnancy.
Can children use Betnovate-C Cream?
Generally not used in children under 12 because of the systemic absorption / neurotoxicity profile of clioquinol. If essential, paediatric dermatology supervision required.
Where can I order Betnovate-C Cream online?
You can order Betnovate-C Cream from MedsBase in standard pack sizes (30 g tube). Orders ship worldwide with discreet packaging. Topical steroid-antibiotic combinations are restricted to specialist supervision in most countries.
For bacterial (rather than fungal) superinfection, compare with Betnovate-N Cream (betamethasone 0.1% + neomycin sulfate) — same corticosteroid base as Betnovate-C, antibiotic co-agent instead of clioquinol.
Gdzie Betnovate-C pairs betamethasone with the antiseptic clioquinol, Betnovate-N Cream (betamethasone 0.1% + neomycin 0.5%) uses the antibiotic neomycin instead — preferred when a defined bacterial pathogen is the concern.
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Ranking według liczby ostatnich zamówień MedsBase — co wybierają inni klienci w tej kategorii.
| Moc | 30 grams |
|---|---|
| Ilość | 1 Tubka, 3 Tubki, 6 Tubaek |
| Postać farmaceutyczna | Cream/s |
| Producent | Glaxo SmithKline |
| Leczenie | Skin infections |
| Marka generyczna | Clotrimazole + Beclometasone |
Betnovate C Cream
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