Quick Answer — What is Mebex?
Mebex to doustna mebendazole 100 mg chewable tablet od Cipla. Mebendazole is a WHO Essential Medicine for pinworm, roundworm, hookworm, and whipworm. Standardowa dawka dla dorosłych: 100 mg as a single dose for pinworm, repeat in 2 weeks. For mixed infection or whipworm: 100 mg twice daily for 3 days.
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Dlaczego warto zamawiać z MedsBase
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What is Mebex?
Mebex is mebendazole 100 mg chewable from Cipla. Mebendazole was the first benzimidazole anthelmintic in routine human use and remains a WHO Essential Medicine. Albendazole has overtaken it as first-line in most settings, but mebendazole has a niche role: it is preferred in patients with concurrent moderate-to-severe hepatic impairment (less hepatic metabolism) and is the agent of choice in some paediatric whipworm protocols.
Mechanizm działania
Mebendazole binds β-tubuliną in parasite cells, preventing microtubule polymerisation. This blocks parasite glucose uptake and depletes glycogen stores — the worm starves over 2–3 days. Mebendazole’s oral bioavailability is very low (< 10%), which is therapeutically useful: high concentrations stay in the gut lumen where intestinal worms live, with minimal systemic exposure.
Mebex indications and dose
| Wskazanie | Dawka | Harmonogram |
|---|---|---|
| Pinworm (Enterobius) | 100 mg | Single dose, repeat at 2 weeks |
| Roundworm (Ascaris) | 100 mg BID | For 3 days |
| Hookworm (Ancylostoma, Necator) | 100 mg BID | For 3 days |
| Włosogłówka (Trichuris) | 100 mg BID | For 3 days; may extend to 5–7 days for heavy load |
| Mixed nematode infection | 100 mg BID | For 3 days |
Tablets can be chewed, swallowed whole, or crushed and mixed with food.
Efekty uboczne
- Częste: mild abdominal pain, transient diarrhoea, flatulence as worms pass
- Rzadsze: headache, dizziness, mild rash
- Rzadko: reversible neutropenia (high-dose long courses), elevated transaminases, alopecia (very rare)
- Very rare: Stevens-Johnson syndrome, toxic epidermal necrolysis
Interakcje lekowe
- Cimetidine — raises mebendazole plasma levels modestly; clinically relevant only in long courses for tissue parasites
- Phenytoin, carbamazepine, rifampicin — reduce mebendazole levels (CYP induction)
- Metronidazol — case reports of Stevens-Johnson syndrome with concurrent use; avoid if possible
Przeciwwskazania
- Hypersensitivity to mebendazole or other benzimidazoles
- Children < 1 year
- First trimester of pregnancy
- Ciężka niewydolność wątroby
Przechowywanie
Store Mebex below 30°C in the original blister, away from light and moisture.
Dlaczego warto zamawiać z MedsBase
Mebex is supplied from a producenta certyfikowanego przez WHO-GMP, zapakowana dyskretnie i wysyłana na całym świecie. Każde zamówienie jest objęte naszą Reshipment Assurance Policy — nigdy nie ponosisz kosztów zagubionej przesyłki.
Najczęściej zadawane pytania
Can I just take one tablet?
For pinworm, yes — one 100 mg dose, then a second at 2 weeks. For roundworm, hookworm, whipworm, or mixed infection, the standard course is 100 mg twice daily for 3 days.
Do I need to fast before Mebex?
No. Mebendazole works locally in the gut lumen and absorption is intentionally low. Take with or without food.
Can my child chew Mebex?
Yes — the tablet is designed to be chewed, swallowed whole, or crushed into food. Chewing is fine for children old enough to spit out anything they dislike (typically age 4+).
How is mebendazole different from albendazole?
Both are benzimidazoles with the same mechanism. Albendazole has higher systemic absorption (better for tissue-dwelling parasites like echinococcus), while mebendazole stays mostly in the gut lumen (preferred for some paediatric protocols and patients with hepatic impairment). For routine intestinal nematodes, both work.
Will Mebex treat tapeworm?
Mebendazole has activity against some intestinal cestodes (Hymenolepis nana) but is NOT first-line for tapeworm. Use niclosamide or praziquantel for confirmed Taenia infection.
How long until the worms are gone?
Adult worms are paralysed within 24–48 hours and pass in faeces over the following 3–5 days. Visible worms in stool are normal and a sign the drug is working. Itching and other symptoms resolve within 1–2 weeks.
Is Mebex safe in pregnancy?
Avoid in the first trimester. After week 13, mebendazole is acceptable for moderate-to-heavy worm burden — discuss with a clinician.
Can I drink alcohol with Mebex?
There is no specific alcohol interaction. Heavy alcohol use stresses the liver, and if the worm load is heavy enough to cause transient transaminase rise, abstaining for the treatment course is prudent.
Does Mebex treat lice or scabies?
No. Mebendazole has no activity against ectoparasites — use ivermectin or permethrin for scabies and pediculicide shampoos or oral ivermectin for lice.
Should I retest after treatment?
For routine pinworm or hookworm in an immunocompetent person with symptom resolution, no follow-up testing is needed. Persistent eosinophilia, weight loss, or recurring symptoms warrant repeat stool ova-and-parasite testing 2–4 weeks after treatment.
For broad-spectrum coverage beyond the standard mebendazole range offered by Mebex (mebendazole 100 mg), Wormentel (fenbendazole 222 / 500 mg) extends antiparasitic activity to Giardia, Trichinella, and tapeworm species not fully addressed by mebendazole monotherapy.
Inne leki przeciwpasożytnicze
- Mebex (mebendazol 100 mg)
- Lupimeb (mebendazole 100 mg)
- ABD 400 (albendazol 400 mg)
- Nemocid (pyrantel pamoate)
- Iverheal (ivermectin)



























Alles okay, kam auch schnell an