Honvan
Honvan (Fosfestrol 120 mg) — high-dose diethylstilbestrol diphosphate oestrogen for advanced metastatic prostate cancer. Significant cardiovascular and thrombotic risk.
✓ Verificat medical de Morgan Ellis — Cercetător farmaceutic · 8 ani de experiență · Ultima recenzie: mai 2026
Răspuns rapid
Honvan — Fosfestrol Tetrasodium 120 mg (Asta Medica). Diethylstilbestrol diphosphate — high-dose estrogen for advanced metastatic prostate cancer. Largely replaced by LHRH agonists; remains in resource-limited or palliative settings.
Ce beneficii oferă MedsBase:
- producător certificat WHO-GMP
- Ambalaj discret în plic simplu
- Livrare în toată lumea
- Evaluat de peste 1.400 de clienți (citește recenziile)
📦 Garanția de retransmitere: dacă comanda dvs. nu a ajuns în 20 de zile lucrătoare de la expediere, o retransmitem fără costuri suplimentare. Citește politica.
De ce să comanzi de la MedsBase
Honvan ships from a WHO-GMP certified manufacturer in plain packaging, billed through a regulated payment processor (the statement descriptor reads a regulated card-payment processor — never MedsBase or any medication name). Every order carries our 20-business-day Reshipment Assurance.
⚠️ Specialist-supervised cancer therapy — this medication is started, monitored, and stopped by an oncologist or haematologist. Dosing depends on tumour type, stage, body surface area, organ function, and concomitant therapy. Self-treatment is not appropriate; the information below is educational and supports informed conversations with your specialist.
Fosfestrol carries substantial cardiovascular risk — DVT, PE, MI, stroke, fluid retention. Use only when modern alternatives (LHRH agonists, abiraterone, enzalutamide) are unavailable or unsuitable. Mandatory thromboprophylaxis discussion with cardiology.
Întrebări frecvente
When is this used?
Diethylstilbestrol diphosphate — high-dose estrogen for advanced metastatic prostate cancer. Largely replaced by LHRH agonists; remains in resource-limited or palliative settings.
Side effects to watch?
Hot flushes, gynaecomastia, fatigue, sexual dysfunction (anti-androgen class effect). Drug-specific monitoring as outlined in the safety boxes above.
Interacțiuni medicamentoase?
Vary by molecule — abiraterone is CYP3A4 substrate; bicalutamide is CYP3A4 substrate. Always disclose all medications. Strong CYP3A4 inhibitors/inducers significantly affect levels.
When should it be stopped?
On disease progression, intolerable toxicity, or successful response with planned treatment break. Always specialist-decided — abrupt cessation can result in transient PSA rise (withdrawal response) which is generally not concerning.
PSA monitoring?
PSA every 1-3 months while on therapy. Rising PSA on castration suggests castration-resistance — may need switch to second-line agents (abiraterone, enzalutamide, docetaxel).
Combined androgen blockade?
LHRH agonist (goserelin, leuprolide) + bicalutamide is a common combination. Maximal androgen blockade has modest survival benefit over LHRH alone.
Bone health?
Long-term androgen deprivation accelerates bone loss. Add a bisphosphonate (zoledronic acid) or denosumab in osteopenia/osteoporosis. Calcium and vitamin D supplementation.
Sarcină?
Anti-androgens are teratogenic — partners must use effective contraception during therapy. Most relevant for younger men with localised disease.
Ce fac dacă uit o doză?
Take when you remember if same day; otherwise skip. Specialist may have specific guidance for missed doses depending on regimen.
Cardiovascular monitoring?
Mandatory for fosfestrol; advised for abiraterone (BP, fluid retention, electrolytes); routine for bicalutamide (occasional CV review).
Other Cancer & Anti-Androgen Therapy
- Calutide — bicalutamide 50 mg — alternative anti-androgen brand
- Xbira — abiraterone 250 mg — CYP17 inhibitor for mCRPC
- Honvan — fosfestrol 120 mg — diethylstilbestrol diphosphate
- Estramustine — estramustine phosphate — alkylator for hormone-refractory disease
- Zoldria — zoledronic acid IV for bone metastases
More options in Anti Cancer Medication
Clasificate în funcție de volumul recent de comenzi MedsBase — ce aleg alți clienți în această categorie.
| Concentrație | 120 mg |
|---|---|
| Cantitate | 30 Comprimate/s, 60 Comprimate/s, 90 Comprimate/s |
| Formă farmaceutică | Comprimat/e |
| Producător | Zydus Pharma |
| Indicație | Prostate Cancer |
| Brand generic | Fosfestrol Tetrasodium |
Honvan
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