Nilol

📦 Fiecare comandă este acoperită de politica noastră de Politica noastră de Reexpediere Garantată — dacă coletul dumneavoastră nu sosește în 20 de zile lucrătoare, îl relivrăm.

De ce să comanzi de la MedsBase

Medicamentele noastre generice sunt procurate de la producători certificați WHO-GMP și expediate la nivel mondial în ambalaje discrete și simple — fără denumirea medicamentului pe exteriorul coletului. Plățile cu cardul sunt procesate printr-un procesor reglementat (descrierile de pe extrasul de cont includ un procesor de plăți cu card reglementat — niciodată “MedsBase” sau numele vreunui medicament). Acceptăm și criptomonede și transferuri bancare SEPA. Fiecare comandă este susținută de Politica noastră de Asigurare pentru Relivrare.

What Is Nilol?

Nilol is an oral tablet from a WHO-GMP certified manufacturer containing:

• Atenolol 50 mg — a cardioselective beta-1 blocker (the same molecule in Atenheal)
• Nifedipine 20 mg — a dihydropyridine calcium-channel blocker (extended-release; same molecule in Depin, Nicardia Retard)

The combination originated in 1980s European cardiology (brand Tenif, Tenoretic) and remains popular in India for patients with both hypertension and stable angina. The two drugs target different mechanisms: atenolol for heart-rate and contractility reduction; nifedipine for direct arterial vasodilation. The beta-blocker prevents the reflex tachycardia that nifedipine monotherapy would otherwise cause.

How Nilol Works

• Atenolol — beta-1 blockade in the SA node reduces heart rate; blockade in ventricular myocardium reduces contractility. Lower cardiac output = lower blood pressure; lower myocardial oxygen demand = less angina.
• Nifedipină — L-type calcium channel blockade in arterial smooth muscle causes direct arterial dilation. Reduces systemic vascular resistance and coronary vasospasm.
• Pereche complementară — bare nifedipine would cause reflex tachycardia (sympathetic response to vasodilation); atenolol blocks that reflex, giving smoother BP control without the palpitation side effect.

Utilizări și dozare

• Combined hypertension + stable angina — indicație principală
• Hipertensiune rezistentă — step-up therapy when single-agent has failed
• Hypertension with coronary artery disease

Doza: one tablet once daily, usually morning. Maximum 2 tablets/day. Target BP <140/90 (or <130/80 with comorbidity).

Monitorizare: baseline + periodic ECG (atenolol bradycardia / nifedipine effect on PR interval), pulse, BP, peripheral oedema (nifedipine commonly causes ankle swelling).

Efecte Secundare

Atenolol-related: fatigue, cold extremities, bradycardia, exercise intolerance, mild fatigue, erectile dysfunction, masked hypoglycaemia in diabetics.

Nifedipine-related:

• Edem la glezne (peripheral swelling) — dose-related; occurs in up to 25% of long-term users
• Flushing, headache (vasodilation)
• Gingival hyperplasia (gum overgrowth)
• Constipație
• Hot flashes, particularly at onset of therapy

Contraindicații

• Asthma / severe COPD (atenolol component)
• Second/third-degree heart block, sinus bradycardia <50, sick sinus syndrome
• Acute decompensated heart failure, cardiogenic shock
• Severe aortic stenosis (nifedipine can worsen)
• Recent myocardial infarction, unstable angina (short-acting nifedipine concern; the ER form is safer)
• Severe renal impairment (eGFR <15 — atenolol dose reduction needed; prefer non-renally-cleared beta-blocker)
• Pregnancy (both components)
• Hipersensibilitate la oricare componentă

Depozitare

Store below 25°C; protect from light.

Why combine atenolol with nifedipine?

Complementary mechanisms and side-effect-mitigation. Bare nifedipine causes reflex tachycardia (sympathetic response to vasodilation); atenolol blocks that reflex, giving smoother BP control. For patients with both hypertension AND stable angina, the two drugs target both diseases simultaneously.

What about the ankle swelling from nifedipine?

Dose-related peripheral oedema occurs in up to 25% of long-term nifedipine users. It is NOT from fluid overload — it is from pre-capillary vasodilation increasing hydrostatic pressure in the lower legs. Treatment: dose reduction, leg elevation, compression stockings, or switch to a non-dihydropyridine CCB (verapamil, diltiazem) or a different vasodilator class (ACE inhibitor, ARB).

Why not use this in pregnancy?

Atenolol is associated with intrauterine growth restriction in pregnancy (more so than other beta-blockers) and neonatal bradycardia/hypoglycaemia. For antihypertensive use in pregnancy, labetalol, methyldopa, and nifedipine-monotherapy (not this FDC) are the preferred options.

Where can I buy Nilol online?

You can buy Nilol (atenolol + nifedipine 50 mg + 20 mg, 30-180 tablets) from MedsBase with discreet packaging and worldwide shipping.

Beta-Blocante și Antihipertensive Asemănătoare

• Beloc — Propranolol 10/20/40 mg
• Betapro SR — Propranolol 80 mg SR
• Metolar — Tartrat de Metoprolol 25/50/100 mg
• Metomac — Metoprolol 25 mg
• P-Nolol — Propranolol 20/40 mg
• Topme — Metoprolol 50 mg
• Răsfoiți toate medicamentele pentru hipertensiune arterială

Alternative conexe

Alte produse din Afecțiuni cronice pe care clienții le vizualizează de asemenea:

• Spray GTN
• Vilano
• Symbicort Turbohaler
• Olmezest AM
• Cosart

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