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Otoflu Eye/Ear Drops

Otoflu (fluconazole + ofloxacin) — combination antifungal + fluoroquinolone for fungal otitis externa and bacterial-fungal external-ear infections. Tympanic membrane intact.

Verificat medical de Morgan Ellis — Cercetător farmaceutic · 8 ani de experiență  · Ultima recenzie: mai 2026

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⚡ Quick Answer — What is Otoflu Eye/Ear Drops?

Otoflu Eye/Ear Drops is a combination eye/ear drop (fluconazole 0.3% + ofloxacin 0.3%) for mixed bacterial-fungal infections of the external ear canal and outer eye. Used 3–4 times daily for 7–10 days. Confirm tympanic membrane is intact before use in the ear.

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De ce să comanzi de la MedsBase

Otoflu Eye/Ear Drops is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our Politica noastră de Reexpediere Garantată — if it has not arrived after 20 business days we reship at no extra cost. Backed by 1,400+ verified customer reviews.

What is Otoflu Eye/Ear Drops?

Otoflu Eye/Ear Drops is manufactured by Sun Pharma as a combination eye and ear drop containing fluconazole 0.3% + ofloxacin 0.3%. The dual antibacterial and antifungal action targets mixed infections of the external ear canal (otitis externa) and superficial outer-eye structures.

Cum funcționează

The fluoroquinolone component (ofloxacin) inhibits bacterial DNA gyrase and topoisomerase IV, killing Gram-positive and Gram-negative bacteria including Pseudomonas. The antifungal component (fluconazole) inhibits fungal cytochrome P450 14α-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane integrity. Together they cover the mixed flora typical of swimmer’s ear and persistent external otitis.

Indicații

  • Otitis externa (swimmer’s ear) with bacterial and fungal involvement
  • Persistent external otitis after antibiotic-alone failure
  • Otomycosis (fungal ear infection)
  • Selected superficial outer-eye infections with mixed flora — under prescriber guidance

Doza

For ear use: 3–4 drops in the affected ear 3–4 times daily. Lie on your side with the affected ear up, instil drops, remain in position for 5 minutes, then sit up. For eye use: 1–2 drops 3–4 times daily. Course duration: 7–10 days.

Confirm tympanic membrane is intact before ear use. Some components of combination ear drops are ototoxic if they reach the middle ear through a perforated tympanic membrane. Always have the eardrum examined before starting ear drops, especially after recent ear infection, ear surgery, or a history of perforation.

Efecte Secundare

Ear: itching, mild stinging, transient hearing changes. Eye: stinging, conjunctival hyperaemia, transient blur. Systemic effects are rare.

Warnings & Contraindications

  • Perforated tympanic membrane (ear use)
  • Hypersensitivity to fluoroquinolones or azoles
  • Viral or herpetic eye disease (eye use) — fluoroquinolones do not treat viral disease
  • Pregnancy — discuss with prescriber
  • Children — generally safe from age 1; consult paediatrician for younger

Depozitare

Store at 15–25°C. Discard 28 days after first opening.

Întrebări frecvente

When is Otoflu Eye/Ear Drops the right choice?

Mixed bacterial-fungal infection of the external ear canal — particularly persistent otitis externa not responding to antibiotic alone, or recurrent otomycosis. Selected outer-eye infections under prescriber guidance.

Why combine antibiotic and antifungal?

Mixed infections occur in moisture-trapped ear canals (swimmer’s ear) and after antibiotic-only courses select for fungal overgrowth. Combination drops cover both groups in one bottle.

What if I have a perforated eardrum?

Don’t use without specialist clearance — some drops are ototoxic if they reach the middle ear. Have the eardrum examined first.

How long does it take to work?

Symptoms usually improve within 48–72 hours. Complete the full course (7–10 days) even if symptoms resolve early.

Can I use Otoflu Eye/Ear Drops for routine eye redness?

No — most red eyes are viral or allergic. Combination drops should be reserved for confirmed mixed bacterial-fungal infection or specialist instruction.

What if my hearing changes?

Stop the drop and contact your prescriber. Possible causes: drop reached middle ear through unrecognised perforation, hypersensitivity, or unrelated cause.

Is Otoflu Eye/Ear Drops safe in pregnancy?

Topical absorption is low. Discuss with your prescriber — there are usually narrower-spectrum alternatives for routine infections.

What about contact lenses?

Stop lenses during ocular treatment.

What if symptoms don't improve?

Re-evaluate. Persistent symptoms may indicate Pseudomonas resistance, atypical organism, foreign body, malignant otitis externa (in diabetics), or wrong diagnosis.

What are the warning signs of malignant otitis externa?

Severe deep ear pain especially at night, granulation tissue in the ear canal, facial nerve weakness, fever — particularly in diabetics or immunocompromised patients. Same-day specialist review.

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Declinare de responsabilitate medicală

The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight — sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.

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Concentrație

0.3% w/v

Cantitate

1 Sticlă/ă, 2 Sticle/ă, 3 Sticle/ă, 6 Sticle/ă

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