Triomune
Triomune (Stavudine + Lamivudine 150 mg + Nevirapine 200 mg) — Cipla older 3-in-1 ART. Replaced by TDF-based regimens in modern WHO guidelines due to mitochondrial toxicity.
✓ Verificat medical de Morgan Ellis — Cercetător farmaceutic · 8 ani de experiență · Ultima recenzie: mai 2026
Răspuns rapid
Triomune — Stavudine 30/40 mg + Lamivudine 150 mg + Nevirapine 200 mg (Cipla Inc). Older 3-in-1 FDC. Stavudine component is mitochondrially toxic; this regimen has been replaced by Trioday (TDF-based) in current WHO guidelines.
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- producător certificat WHO-GMP
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📦 Reshipment Assurance: if your order has not arrived 20 business days after dispatch, we reship it at no extra cost. Read the policy.
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Triomune ships from a WHO-GMP certified manufacturer in plain packaging, billed through a regulated payment processor (the statement descriptor reads a regulated card-payment processor — never MedsBase or any medication name). Every order carries our 20-business-day Reshipment Assurance.
If your regimen contains lamivudine, tenofovir, or emtricitabine, these also treat HBV. Test HBsAg and HBV DNA before starting. Stopping abruptly can cause severe HBV flare in co-infected patients — always under hepatology supervision.
>95% adherence is mandatory. Take at the same time daily, with or without food per the regimen instructions. Missed doses risk resistance, viral rebound, and treatment failure across multiple drug classes simultaneously.
Why fixed-combination regimens
Single-tablet regimens reduce pill burden, improve adherence (proven in multiple trials), simplify dosing, and reduce stigma. They are the preferred form of ART worldwide where available. The trade-off is reduced flexibility — if one component is contraindicated (renal disease, HBV monoinfection, drug interaction), the regimen must be replaced rather than partially adjusted.
Întrebări frecvente
What does each component do?
Each fixed-combination has a specific role: NRTI backbone (typically two NRTIs) provides the core of viral suppression; the third agent (NNRTI, INSTI, or PI) closes the regimen. Look at the strengths panel for the exact components.
What if I’m intolerant to one component?
Switch to separate components or a different fixed-combination. Never cut tablets to reduce the dose of an offending component — that risks resistance.
Drug interactions?
Depend on components. Most NRTIs have few interactions; NNRTIs and PIs have many CYP-mediated interactions. Always disclose all medications. Use the Liverpool HIV-DDI database (hiv-druginteractions.org).
Pregnancy?
Safety depends on components. TDF + 3TC + EFV (Trioday) is widely used in pregnancy with extensive safety data. Switch from regimens containing problematic components (high-dose ritonavir, cobicistat, some PIs) under specialist guidance.
Ce fac dacă uit o doză?
Take it when you remember if <6 hours late. If >6 hours late, skip and resume — do not double up. Repeated missed doses risk multi-class resistance.
HBV testing?
Critical — test HBsAg and HBV DNA before starting any regimen containing lamivudine, tenofovir, or emtricitabine. These also treat HBV; stopping risks hepatic flare.
Resistance testing?
Genotypic resistance testing is recommended at HIV diagnosis, before any new regimen, and at virological failure.
U=U?
Yes — Undetectable = Untransmittable. Consistent <200 copies/mL viral load on ART eliminates sexual HIV transmission risk.
Lifelong therapy?
Yes — current ART is lifelong. With consistent adherence, life expectancy approaches that of HIV-negative peers.
When should I see my HIV team?
Routine: every 3-6 months once stable, annual STI screening, vaccinations, cardiometabolic screening. Earlier if symptoms or treatment-failure signals.
Other HIV & Antiviral Medications
- Trioday — TDF + 3TC + EFV — single-tablet regimen by Cipla
- Triomune — d4T + 3TC + NVP — older 3-in-1 (stavudine-based)
- Zepdon — raltegravir 400 mg — integrase inhibitor
- Abamune L — abacavir + lamivudine — alternative NRTI backbone
- Tenvir L — tenofovir + lamivudine — alternative NRTI backbone
More options in HIV Medication
Clasificate în funcție de volumul recent de comenzi MedsBase — ce aleg alți clienți în această categorie.
| Concentrație | 30+150+200 mg, 40+150+200 mg |
|---|---|
| Cantitate | 30 Tablet/s, 60 Tablet/s, 90 Tablet/s |
| Formă farmaceutică | Capsule/s |
| Producător | Cipla Inc |
| Indicație | HIV Infection |
| Brand generic | Stavudine + Lamivudine + Nevirapine |
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