Lupimeb

📦 Fiecare comandă este acoperită de politica noastră de Politica noastră de Reexpediere Garantată — dacă coletul dumneavoastră nu sosește în 20 de zile lucrătoare, îl relivrăm.

De ce să comanzi de la MedsBase

Medicamentele noastre generice sunt procurate de la producători certificați WHO-GMP și expediate la nivel mondial în ambalaje discrete și simple — fără denumirea medicamentului pe exteriorul coletului. Plățile cu cardul sunt procesate printr-un procesor reglementat (descrierile de pe extrasul de cont includ un procesor de plăți cu card reglementat — niciodată “MedsBase” sau numele vreunui medicament). Acceptăm și criptomonede și transferuri bancare SEPA. Fiecare comandă este susținută de Politica noastră de Asigurare pentru Relivrare.

What is Lupimeb?

Lupimeb is mebendazole 100 mg chewable from Lupin. Mebendazole was the first benzimidazole anthelmintic in routine human use and remains a WHO Essential Medicine. Albendazole has overtaken it as first-line in most settings, but mebendazole has a niche role: it is preferred in patients with concurrent moderate-to-severe hepatic impairment (less hepatic metabolism) and is the agent of choice in some paediatric whipworm protocols.

Mecanism de acțiune

Mebendazole binds β-tubulină in parasite cells, preventing microtubule polymerisation. This blocks parasite glucose uptake and depletes glycogen stores — the worm starves over 2–3 days. Mebendazole’s oral bioavailability is very low (< 10%), which is therapeutically useful: high concentrations stay in the gut lumen where intestinal worms live, with minimal systemic exposure.

Lupimeb indications and dose

Tablets can be chewed, swallowed whole, or crushed and mixed with food.

Efecte secundare

• Frecvente: mild abdominal pain, transient diarrhoea, flatulence as worms pass
• Mai puțin frecvente: headache, dizziness, mild rash
• Rare: reversible neutropenia (high-dose long courses), elevated transaminases, alopecia (very rare)
• Very rare: Stevens-Johnson syndrome, toxic epidermal necrolysis

Interacțiuni medicamentoase

• Cimetidina — raises mebendazole plasma levels modestly; clinically relevant only in long courses for tissue parasites
• Phenytoin, carbamazepine, rifampicin — reduce mebendazole levels (CYP induction)
• Metronidazole — case reports of Stevens-Johnson syndrome with concurrent use; avoid if possible

Contraindicații

• Hypersensitivity to mebendazole or other benzimidazoles
• Children < 1 year
• First trimester of pregnancy
• Severe hepatic impairment

Depozitare

Store Lupimeb below 30°C in the original blister, away from light and moisture.

De ce să comanzi de la MedsBase

Lupimeb is supplied from a producător certificat WHO-GMP, ambalată discret și expediată la nivel mondial. Fiecare comandă este acoperită de asigurarea noastră Politica noastră de Reexpediere Garantată — nu suportați niciodată costul unui colet pierdut.

Întrebări frecvente

Can I just take one tablet?

For pinworm, yes — one 100 mg dose, then a second at 2 weeks. For roundworm, hookworm, whipworm, or mixed infection, the standard course is 100 mg twice daily for 3 days.

Do I need to fast before Lupimeb?

No. Mebendazole works locally in the gut lumen and absorption is intentionally low. Take with or without food.

Can my child chew Lupimeb?

Yes — the tablet is designed to be chewed, swallowed whole, or crushed into food. Chewing is fine for children old enough to spit out anything they dislike (typically age 4+).

How is mebendazole different from albendazole?

Both are benzimidazoles with the same mechanism. Albendazole has higher systemic absorption (better for tissue-dwelling parasites like echinococcus), while mebendazole stays mostly in the gut lumen (preferred for some paediatric protocols and patients with hepatic impairment). For routine intestinal nematodes, both work.

Will Lupimeb treat tapeworm?

Mebendazole has activity against some intestinal cestodes (Hymenolepis nana) but is NOT first-line for tapeworm. Use niclosamide or praziquantel for confirmed Taenia infection.

How long until the worms are gone?

Adult worms are paralysed within 24–48 hours and pass in faeces over the following 3–5 days. Visible worms in stool are normal and a sign the drug is working. Itching and other symptoms resolve within 1–2 weeks.

Is Lupimeb safe in pregnancy?

Avoid in the first trimester. After week 13, mebendazole is acceptable for moderate-to-heavy worm burden — discuss with a clinician.

Can I drink alcohol with Lupimeb?

There is no specific alcohol interaction. Heavy alcohol use stresses the liver, and if the worm load is heavy enough to cause transient transaminase rise, abstaining for the treatment course is prudent.

Does Lupimeb treat lice or scabies?

No. Mebendazole has no activity against ectoparasites — use ivermectin or permethrin for scabies and pediculicide shampoos or oral ivermectin for lice.

Should I retest after treatment?

For routine pinworm or hookworm in an immunocompetent person with symptom resolution, no follow-up testing is needed. Persistent eosinophilia, weight loss, or recurring symptoms warrant repeat stool ova-and-parasite testing 2–4 weeks after treatment.

Patients seeking extended parasite coverage beyond Lupimeb (mebendazole 100 mg) may consider Wormentel (fenbendazole 222 / 500 mg) as a fenbendazole alternative in the same benzimidazole class but with a broader organism spectrum covering Giardia, tapeworm, and Trichinella.

Alte Medicamente Antiparazitare

• Mebex (mebendazol 100 mg)
• Lupimeb (mebendazole 100 mg)
• ABD 400 (albendazol 400 mg)
• Nemocid (pamoat de pirantel)
• Iverheal (ivermectin)

Mai multe opțiuni în Tratamentul Oxiurilor

Clasificate în funcție de volumul recent de comenzi MedsBase — ce aleg alți clienți în această categorie.

Iverheal

US$36.00 – US$699.00価格帯: US$36.00～US$699.00

Prazinec

US$11.00 – US$56.00価格帯: US$11.00～US$56.00

ABD 400 (Albendazol)

US$27.00 – US$122.00価格帯: US$27.00～US$122.00

Ivimec

US$36.00 – US$575.00価格帯: US$36.00～US$575.00