Maxiliv Injection
Maxiliv Injection (Glutathione 600 mg per IV vial) — antioxidant tripeptide for chemotherapy-induced peripheral neuropathy and oxidative liver stress. Hospital-administered. Not for cosmetic skin-whitening (FDA-warned). WHO-GMP certified manufacturer.
✓ Verificat medical de Morgan Ellis — Cercetător farmaceutic · 8 ani de experiență · Ultima recenzie: mai 2026
⚡ Quick Answer — What is Maxiliv Injection?
Maxiliv Injection este reduced glutathione (GSH) 600 mg per vial for IV use — a tripeptide antioxidant (glutamate-cysteine-glycine) used clinically for oxidative liver stress, cisplatin- or oxaliplatin-induced peripheral neuropathy, and adjunct therapy in chemotherapy. It is administered intravenously by a healthcare professional. Glutathione is the body’s principal intracellular antioxidant, neutralising reactive oxygen species and conjugating reactive electrophiles for renal/biliary excretion.
📦 Fiecare comandă este acoperită de politica noastră de Politica noastră de Reexpediere Garantată — dacă coletul dumneavoastră nu sosește în 20 de zile lucrătoare, îl relivrăm.
De ce să comanzi de la MedsBase
Medicamentele noastre generice sunt procurate de la producători certificați WHO-GMP și expediate la nivel mondial în ambalaje discrete și simple — fără denumirea medicamentului pe exteriorul coletului. Plățile cu cardul sunt procesate printr-un procesor reglementat (descrierile de pe extrasul de cont includ un procesor de plăți cu card reglementat — niciodată “MedsBase” sau numele vreunui medicament). Acceptăm și criptomonede și transferuri bancare SEPA. Fiecare comandă este susținută de Politica noastră de Asigurare pentru Relivrare.
De ce să comanzi de la MedsBase
Maxiliv Injection is supplied from a producător certificat WHO-GMP. Every order ships discreetly worldwide and is covered by our Politica noastră de Reexpediere Garantată — if it does not arrive within 20 business days, we reship at no cost. IV glutathione is used as supportive therapy in oncology and hepatology — not as a cosmetic intervention. Clinical doses, frequencies, and administration protocols are determined by the treating physician.
Mechanism
Glutathione is a thiol tripeptide that exists in reduced (GSH) and oxidised (GSSG) forms; the reduced form donates electrons to neutralise hydrogen peroxide and lipid peroxides via glutathione peroxidase, and conjugates reactive electrophiles via glutathione-S-transferase. Cellular glutathione is depleted by oxidative stress, paracetamol overdose, alcohol, ageing, and several disease states. IV glutathione transiently raises circulating levels; cellular uptake of intact GSH is limited, but the molecule is hydrolysed and the constituent amino acids (especially cysteine, the rate-limiting precursor) support intracellular re-synthesis.
Clinical indications
- Cisplatin- and oxaliplatin-induced peripheral neuropathy (Schmitt 2009 trial — preserved sensory nerve function on serial nerve-conduction studies)
- Oxidative liver stress in chronic hepatitis, fatty liver, post-anaesthetic, post-chemotherapy
- Acute paracetamol toxicity (N-acetylcysteine is the standard antidote that replenishes intracellular GSH; IV GSH is supplementary)
- Some Parkinson’s disease research protocols (off-label, low evidence)
- Idiopathic pulmonary fibrosis adjunct (low evidence)
Doses (clinician-determined)
Cisplatin-induced neuropathy: 1.5–2.4 g IV before each chemotherapy cycle. Hepatic support: 600 mg–1.2 g once daily or every other day. Always slow IV push or short infusion in compatible diluent (typically 5 percent dextrose or normal saline; check compatibility per local protocol).
Efecte secundare
- Injection-site reactions, mild venous irritation
- Sulphurous taste / smell during infusion
- Hypersensitivity (rare; thiol allergy, asthma triggers)
- Stevens-Johnson syndrome / TEN (rare but reported, particularly with frequent unsupervised cosmetic dosing)
- Thyroid dysfunction with chronic high-dose use (FDA cosmetic-use warning)
- Renal impairment (rare)
Cautions
- Severe asthma (sulphite/thiol exacerbation risk)
- Active malignancy — specialist oncology decision (concern that antioxidant therapy could blunt chemo cytotoxicity offset by neuroprotection benefit)
- Pregnancy and breastfeeding — insufficient data, avoid unless clinical benefit is clear
- Renal impairment — reduce dose
Întrebări frecvente
Can I have IV glutathione for skin-whitening?
No — this is not a recognised medical indication. The FDA has issued specific warnings against unsupervised IV glutathione for cosmetic use due to serious adverse-event reports.
Does it really protect against chemo-induced neuropathy?
Schmitt 2009 (Italian Multicentre Cooperative Group) showed reduced sensory neuropathy on cisplatin in colorectal cancer patients pre-treated with IV glutathione. Several subsequent trials have shown variable effects. It remains an option in oncology supportive care but is not universally adopted.
How is it administered?
By a healthcare professional, intravenously, after reconstitution with a compatible diluent. Self-administration is unsafe and not endorsed.
Are there oral alternatives?
Liposomal oral glutathione has modest absorption. N-acetylcysteine (NAC) 600–1200 mg/day is a more bioavailable cysteine precursor and is the standard oral approach to raising intracellular glutathione.
Is it safe in pregnancy?
Insufficient data — avoid unless the clinical situation strongly justifies it. NAC has a longer pregnancy safety record.
Can I take it with chemotherapy?
Only under oncology supervision. The interaction between antioxidant supplementation and chemotherapy efficacy is debated; clinical decisions need to be made within the multidisciplinary team.
Why does it smell of sulphur?
Glutathione contains a sulfhydryl (-SH) group. The smell during infusion is harmless and dissipates within minutes.
How often should I have it?
Determined by the treating clinician. Frequent dosing (more than once weekly) is not supported by clinical evidence and increases risk of adverse reactions.
Depozitare
Below 25°C, protect from light. Discard reconstituted solution if not used within the local protocol’s stability window (typically 2–4 hours).
Ce fac dacă uit o doză?
Discuss with the treating clinician. Do not self-administer or arrange unsupervised infusions.
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Clasificate în funcție de volumul recent de comenzi MedsBase — ce aleg alți clienți în această categorie.
| Concentrație | 600 mg |
|---|---|
| Cantitate | 1 Vial/s, 2 Vial/s, 3 Vials/s, 6 Vial/s |
Maxiliv Injection
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