Carditrex
Carditrex (Methotrexate 2.5 mg) — Cipla antifolate for haematological malignancies, severe psoriasis, and rheumatoid arthritis. WEEKLY dosing for autoimmune use only.
✓ Medically reviewed by Morgan Ellis — Pharmacy Researcher · 8 years experience · Last reviewed: May 2026
Quick Answer
Carditrex — Methotrexate 2.5 mg (Cipla Inc). Antifolate for haematological malignancies (ALL, lymphoma), trophoblastic disease, severe psoriasis, rheumatoid arthritis. Multiple dose schedules (weekly low-dose for autoimmune; high-dose IV for cancer with leucovorin rescue).
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⚠️ Specialist-supervised cancer therapy — this medication is started, monitored, and stopped by an oncologist or haematologist. Dosing depends on tumour type, stage, body surface area, organ function, and concomitant therapy. Self-treatment is not appropriate; the information below is educational and supports informed conversations with your specialist.
MTX for autoimmune disease is taken ONCE A WEEK — daily dosing has caused fatal toxicity. Always confirm the schedule. Co-prescribe folic acid 5 mg/week (different day) to reduce toxicity. Mandatory FBC, LFTs, renal function before each weekly dose for first 6 months. Cancer high-dose IV regimens require leucovorin rescue + plasma MTX monitoring.
Frequently Asked Questions
When is this used?
Antifolate for haematological malignancies (ALL, lymphoma), trophoblastic disease, severe psoriasis, rheumatoid arthritis. Multiple dose schedules (weekly low-dose for autoimmune; high-dose IV for cancer with leucovorin rescue). Specific protocols are oncologist-determined.
Side effects?
Class-typical: myelosuppression, nausea, alopecia, mucositis, fatigue. Specific toxicities depend on the drug — see safety boxes above.
Drug interactions?
Cancer chemotherapy has multiple critical interactions. Always disclose all medications including herbals and supplements. Anticoagulants, anticonvulsants, antibiotics, antifungals, and antivirals all need review.
Pregnancy?
Cytotoxic chemotherapy is teratogenic. Effective contraception during and for 6 months after for both partners.
Monitoring?
Specialist-determined — typically FBC, renal/liver function, electrolytes before each cycle. Drug-specific tests (echocardiogram for anthracyclines, audiometry for cisplatin, etc.).
What if I miss a dose?
Oral cytotoxics: skip the missed dose, do not double up, contact your oncology team. IV: dosing is strictly scheduled — discuss any delay or missed cycle with the specialist.
Storage?
Oral cytotoxics: at room temperature, away from children, in original blister. Hand washing after handling tablets. Pregnant household members should not handle broken tablets.
Vaccines?
Live vaccines are contraindicated during chemotherapy. Inactivated vaccines (annual influenza, pneumococcal) are recommended. Coordinate with oncology for timing.
Long-term complications?
Class-dependent: secondary malignancy, infertility, cardiotoxicity, neuropathy. Discuss with oncology — fertility preservation may be relevant before starting.
When is treatment finished?
Determined by tumour response, treatment intent (curative vs palliative), and toxicity. Imaging and clinical assessment guide ongoing therapy.
Other Cancer Medications
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- Xbira — abiraterone 250 mg — CYP17 inhibitor for metastatic prostate cancer
- Zoldria — zoledronic acid IV — for bone metastases and hypercalcaemia
- Actorise — darbepoetin alfa — for chemotherapy-induced anaemia
More options in Anti Cancer Medication
Ranked by recent MedsBase order volume — what other customers in this category are picking.
| Strength | 2.5 mg |
|---|---|
| Quantity | 30 Tablet/s, 60 Tablet/s, 90 Tablet/s |
| Pharma Form | Tablet/s |
| Manufacturer | Cadila Pharmaceuticals |
| Treatment | Anti Cancer |
| Generic Brand | Methotrexate |
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