⚡ Quick Answer — What is Cipmox?
Cipmox is an amoxicillin capsule (250 mg / 500 mg, Cipla) — a first-line aminopenicillin antibiotic for ear, sinus, throat, dental, urinary, and respiratory tract infections. Standard adult dose is 500 mg three times daily for 5–7 days. Take with or without food. Always finish the full course.
📦 Всяка поръчка е покрита от нашата Политика за повторна изпратка — ако вашата пратка не пристигне в рамките на 20 работни дни, ние я изпращаме отново.
Защо да поръчвате от MedsBase
Нашите генерични лекарства се доставят от производители, сертифицирани от WHO-GMP, и се изпращат по целия свят в дискретна, обикновена опаковка — без име на лекарството външно на пратката. Плащанията с карта се обработват чрез регулиран процесор (описанието на извлечението включва регулиран процесор за плащане с карта — никога “MedsBase” или име на лекарство). Приемат се също криптовалути и банков превод SEPA. Всяка поръчка е подкрепена от нашата политика за гарантирано преизпращане.
How Cipmox works
Cipmox contains амоксицилин, an aminopenicillin that blocks bacterial cell-wall synthesis by binding penicillin-binding proteins (PBP1A, PBP1B, PBP3). It is bactericidal against many Gram-positive cocci (Streptococcus pyogenes, Streptococcus pneumoniae, Enterococcus faecalis), some Gram-negative rods (Haemophilus influenzae, Helicobacter pylori, sensitive E. coli, Salmonella, Shigella), and oral anaerobes. It does not cover Pseudomonas, staphylococci that produce beta-lactamase, or atypical respiratory pathogens (Mycoplasma, Chlamydia, Legionella).
Показания и дозиране
| Показание | Стандартна доза | Продължителност |
|---|---|---|
| Mild–moderate respiratory tract infection (sinusitis, otitis media, CAP) | 500 mg three times daily | 5–7 дни |
| Severe pneumonia / non-MRSA pneumonia (high-dose) | 1 g three times daily | 7–10 days |
| Streptococcal pharyngitis / tonsillitis | 500 mg three times daily or 1 g twice daily | 10 days (eradication) |
| Uncomplicated UTI in pregnancy (sensitive E. coli) | 500 mg three times daily | 5–7 дни |
| Dental abscess / pre-procedural endocarditis prophylaxis | 2 g single dose 60 min before procedure | Еднократна доза |
| Helicobacter pylori triple therapy (with PPI + clarithromycin or metronidazole) | 1 g twice daily | 14 days |
| Lyme disease (early localised, pregnancy) | 500 mg three times daily | 14–21 days |
Renal dose adjustment: CrCl 10–30 mL/min — extend interval to 12-hourly. CrCl <10 mL/min — every 24 h. Haemodialysis — dose after dialysis.
Paediatric (oral suspension): 25–45 mg/kg/day divided 8-hourly for ordinary infections; 80–90 mg/kg/day divided 12-hourly for high-dose AOM in regions with intermediate-resistant S. pneumoniae.
Странични ефекти
- Gastrointestinal: diarrhoea, nausea, vomiting, anorexia (5–20%). Diarrhoea more common with ampicillin/amp+clox than amoxicillin.
- Хиперчувствителност: maculopapular rash (especially with concurrent EBV — characteristic ampicillin rash, not a true allergy), urticaria, angioedema, anaphylaxis. True IgE-mediated reactions are rare (~0.01% anaphylaxis) but cross-react with all beta-lactams to varying degrees.
- Candidiasis: oral thrush and vulvovaginal candidiasis are common with prolonged courses.
- Clostridioides difficile colitis: watch for new-onset watery diarrhoea, abdominal pain, fever during or up to 8 weeks after treatment.
- Чернодробни: mild transaminase elevation; cholestatic hepatitis is rare but reported.
- Haematological: rare interstitial nephritis, neutropenia, eosinophilia with prolonged courses.
Contraindications & cautions
- Known IgE-mediated penicillin allergy (anaphylaxis, severe urticaria, angioedema, Stevens–Johnson) — choose a non-beta-lactam class.
- History of cephalosporin- or carbapenem-induced anaphylaxis — variable cross-reactivity.
- Active glandular fever (infectious mononucleosis) — high risk of widespread maculopapular rash; choose a different agent if possible.
- Severe renal impairment without dose adjustment.
Взаимодействия с лекарства
| Лекарство | Ефект | Действие |
|---|---|---|
| Метотрексат | Penicillins reduce renal clearance; risk of methotrexate toxicity | Monitor levels; consider holding antibiotic if methotrexate >100 mg/week |
| Combined oral contraceptive | Theoretical reduction in efficacy via gut-flora suppression — modern data show no clinically significant reduction | Counsel on additional barrier method only if breakthrough bleeding occurs |
| Пробенецид | Reduces renal tubular secretion of penicillin; raises serum levels | Sometimes used clinically to extend dosing interval |
| Allopurinol | Increases incidence of penicillin-related rash | No dose change; counsel |
| Warfarin | Variable INR effect; case reports of both potentiation and reduction | Check INR 3–5 days into therapy |
Бременност и кърмене
Aminopenicillins are category B (FDA) — extensively used in pregnancy and considered safe across all trimesters. Amoxicillin is the drug of choice for asymptomatic bacteriuria, group B streptococcal prophylaxis, and uncomplicated pyelonephritis in pregnancy. Excretion in breast milk is minimal and considered compatible with breastfeeding.
Съхранение
Съхранявайте при температура под 25 °C, далече от пряка слънчева светлина и влага. Пазете в оригиналната опаковка. Пазете извън обсега на децата. Изхвърлете всички неизползвани таблетки след отпечатаната дата на изтичане на срока на годност — разградените антибиотици могат да загубят ефективност или да освободят продукти на разграждане.
Този лекарствен продукт е ефективен само срещу бактериални инфекции. Не го използвайте при вирусни заболявания (обикновена настинка, повечето възпаления на гърлото, грип, COVID-19), не спирайте лечението преждевременно, когато се почувствате по-добре, и не съхранявайте остатъци за бъдещи инфекции. Злоупотребата води до устойчиви бактерии като MRSA, ESBL и CRE — СЗО класифицира антимикробната резистентност сред топ 10 глобални заплахи за общественото здраве.
Често задавани въпроси
Should I take Cipmox with food?
Cipmox (amoxicillin) can be taken with or without food — absorption is barely affected, so take it with food if it upsets your stomach.
Колко бързо ще се почувствам по-добре?
Most patients with simple respiratory or urinary infections feel meaningfully better within 48–72 hours. If you are no better at 72 hours — or if you are getting worse — seek medical review. A bacterial culture or alternative antibiotic class may be needed.
Мога ли да пия алкохол?
There is no direct interaction between aminopenicillins and alcohol — but heavy drinking weakens immune defences and slows recovery. Light social use is acceptable; avoid binge drinking during the course.
Какво да направя, ако пропусна доза?
Take it as soon as you remember. If you are within 2 hours of the next scheduled dose, skip the missed dose — never double up. Repeated missed doses risk treatment failure and resistance emergence.
Is the rash I developed a true penicillin allergy?
A delayed maculopapular rash 5–10 days into a course is usually a non-IgE reaction and not a true allergy — re-challenge with future penicillins is often safe under clinical guidance. Hives, swelling of face/lips, wheeze or anaphylaxis ARE true allergies — record on your medical notes and avoid all penicillins.
Why not use this for a viral cold or flu?
Aminopenicillins are bactericidal — they only work on bacteria. Using them for viral illnesses provides no clinical benefit and accelerates resistance in your own gut and respiratory flora.
Do I need to take a probiotic alongside?
Saccharomyces boulardii or a multi-strain Lactobacillus product taken several hours apart from the antibiotic may reduce antibiotic-associated diarrhoea risk in adults — evidence strength is moderate. Stop if any GI symptoms.
Can I take this if I am also on methotrexate?
Penicillins can raise methotrexate levels and increase toxicity (mucositis, marrow suppression). Inform your prescriber — methotrexate may need to be held during the antibiotic course or levels checked.
Will it affect my contraceptive pill?
Modern evidence does not support a clinically significant reduction in pill efficacy with most antibiotics including penicillins. Continue your usual pill schedule — but use additional protection if you experience vomiting or diarrhoea, which can affect absorption.
What should I do if symptoms have not improved by day 3?
Return for medical review. The cause may be viral, the bacterium may be resistant, or there may be an abscess that requires drainage. Do not simply lengthen the course or escalate the dose without specialist input.
Други антибиотици и противомикробни лекарства
- Augmentin (Amoxicillin + Clavulanic acid) — broader spectrum
- Cetil (Cefuroxime) — second-generation cephalosporin
- Azee (Azithromycin) — penicillin-allergy alternative for respiratory infection
- Cifran (Ciprofloxacin) — fluoroquinolone for UTI / GI
- Doxt (Doxycycline) — атипична пневмония / ИППП






























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