Rapact
Rapact (Sirolimus 5/10 mg) — Sun Pharma mTOR inhibitor for solid-organ transplant maintenance, lymphangioleiomyomatosis, tuberous sclerosis-associated tumours.
✓ Медицински преглед от Morgan Ellis — Фармацевтичен изследовател · 8 години опит · Последен преглед: май 2026 г.
Бърз отговор
Rapact — Sirolimus (Rapamycin) 5/10 mg (Sun Pharma). mTOR inhibitor for solid-organ transplant maintenance immunosuppression, lymphangioleiomyomatosis (LAM), tuberous sclerosis-associated angiomyolipomas, certain cancers. Therapeutic drug monitoring (target trough 5-15 ng/mL).
Какво получавате с MedsBase:
- СЗО-GMP сертифициран производител
- Дискретна опаковка в обикновен плик
- Доставка по целия свят
- Оценено от над 1,400 клиенти (прочети ревюта)
📦 Гаранция за преизпращане: ако поръчката ви не е пристигнала в рамките на 20 работни дни след изпращане, я преизпращаме без допълнителни такси. Прочети политиката.
Защо да поръчвате от MedsBase
Rapact ships from a WHO-GMP certified manufacturer in plain packaging, billed through a regulated payment processor (the statement descriptor reads a regulated card-payment processor — never MedsBase or any medication name). Every order carries our 20-business-day Reshipment Assurance.
⚠️ Specialist-supervised cancer therapy — this medication is started, monitored, and stopped by an oncologist or haematologist. Dosing depends on tumour type, stage, body surface area, organ function, and concomitant therapy. Self-treatment is not appropriate; the information below is educational and supports informed conversations with your specialist.
Immunosuppressants need ongoing specialist supervision (transplant, rheumatology, or haematology). Drug levels (cyclosporine, sirolimus, tacrolimus), FBC, LFTs, renal function, lipids, glucose, BP — all need regular monitoring. Infection surveillance is mandatory. Vaccination status must be optimised before starting; live vaccines contraindicated during therapy.
Long-term immunosuppression increases risks: opportunistic infections (PCP, CMV, EBV-driven PTLD), bacterial/fungal infection, reactivation of latent TB or HBV/HCV. Increased risk of skin cancer (especially squamous cell), lymphoproliferative disease, and other malignancies. Annual skin checks, regular cancer surveillance per guidelines.
Често задавани въпроси
When is this used?
mTOR inhibitor for solid-organ transplant maintenance immunosuppression, lymphangioleiomyomatosis (LAM), tuberous sclerosis-associated angiomyolipomas, certain cancers. Therapeutic drug monitoring (target trough 5-15 ng/mL). Always specialist-supervised — transplant, rheumatology, haematology, or oncology context.
Why is monitoring needed?
Therapeutic drug monitoring (cyclosporine, sirolimus, tacrolimus): trough levels target organ-protection without toxicity. Renal function: most are nephrotoxic. Lipids/glucose: metabolic effects. FBC: marrow suppression.
Лекарствени взаимодействия?
Critical class — strong CYP3A4 substrates (calcineurin inhibitors, mTOR inhibitors). Many interactions: antifungals raise levels (often dramatically — even 5-10×), rifampicin drops levels (rejection risk), grapefruit raises levels. Any new medication should be checked first.
Vaccines?
Inactivated vaccines fine; live vaccines contraindicated during therapy. Optimise vaccinations BEFORE starting — pneumococcal, annual influenza, hepatitis B, varicella, MMR, HPV as appropriate.
Бременност?
Mycophenolate is teratogenic — strict contraception. Cyclosporine, tacrolimus, azathioprine are used in pregnancy with specialist supervision. mTOR inhibitors generally avoided. Always discuss family planning with specialist.
Cancer screening?
Skin checks every 6-12 months (lifelong skin cancer risk). Cervical cytology more frequent. Lymph nodes — monitor for lymphoproliferative disease.
Infections?
Cotrimoxazole prophylaxis for PCP first 6-12 months post-transplant. CMV monitoring. TB screening before starting. Ongoing infection vigilance — fever needs prompt assessment.
Sun protection?
Daily broad-spectrum SPF 50+ from the day of transplant onwards. Annual dermatology review. Skin cancer is the most common post-transplant malignancy.
Какво да направя, ако пропусна доза?
Take when you remember if same day; if >12 hours late, skip and resume next dose. Do not double up. Consistent levels matter — discuss adherence with your transplant team.
Stopping?
Never stop without specialist guidance — risks acute rejection (transplant) or disease flare (autoimmune). Tapers happen over months, not days, and only when clinically appropriate.
Other Immunosuppressant & Cancer Medications
- Mycept — mycophenolate mofetil 250 mg — alternative MMF brand
- Mycofit — mycophenolate mofetil 500 mg
- Cyclophil ME — cyclosporine ME 25/50/100 mg
- Renodapt S — mycophenolate sodium 360 mg — enteric-coated
- Rapact — sirolimus 5/10 mg — mTOR inhibitor
More options in Anti Cancer Medication
Класирани според скорошния обем на поръчки в MedsBase — какво избират други клиенти в тази категория.
| Сила | 5 mg, 10 mg |
|---|---|
| Количество | 28 Таблетки, 56 Таблетки, 84 Таблетки |
| Фармацевтична форма | Таблетки |
| Производител | Natco Pharma |
| Лечение | Breast cancer, Pancreatic cancer, Lung cancer |
| Generic Brand | Sirolimus |
Rapact
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Rapact
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