Ливиал

✅ Relieves menopausal symptoms
✅ Improves bone density
✅ Enhances libido
✅ Protects against osteoporosis
✅ Regulates hormonal balance

Livial contains Tibolone.

SKU: N/A Категория: Преглед на категориите, Хормонална заместителна терапия (HRT) при менопауза, Женско здраве Етикет: Ливиал, Tibolone

✓ Медицински преглед от Morgan Ellis — Фармацевтичен изследовател · 8 години опит · Последен преглед: май 2026 г.

Купувайте повече, спестявайте повече Цена на таблетка

28 таблетки

US$2.00/таблетка

US$56.00

56 таблетки

US$1.93/tablet · спестете 4%

US$108.00

84 таблетки

US$1.86/tablet · спестяване на 7%

156.00 щ.д.

168 таблетки НАЙ-ДОБРА ЦЕНА

US$1.71/таблетка · спестявате 14%

US$288.00

Шифровано плащане

Криптовалути - 10% отстъпка

Дискретна доставка по целия свят

1,400+ клиенти · 50+ държави

Сила

2.5 mg

Количество

28 таблетки
56 таблетки
84 таблетки
168 таблетки

Изчисти

💡 Бърз отговор

Ливиал е tibolone 2.5 mg, a synthetic steroid that produces mild estrogenic, progestogenic, and androgenic activity after tissue-specific metabolism. Used for menopausal symptom relief and osteoporosis prevention in women at least 1 year post-menopause. Unlike standard combined HRT, tibolone does not require a separate progestin. Has a distinct risk profile — slightly elevated stroke risk in women over 60, and slightly increased recurrence risk in women with a history of breast cancer.

Какво получавате с MedsBase: Производител, сертифициран от WHO-GMP · Дискретна опаковка · Доставка по целия свят · Над 1400 потвърдени отзива от клиенти

📦 Всяка поръчка е покрита от нашата Политика за повторна изпратка — ако вашата пратка не пристигне в рамките на 20 работни дни, ние я изпращаме отново.

🔒 What you get with MedsBase: WHO-GMP certified manufacturer · Discreet plain packaging (no medication name on the outside) · Worldwide shipping · Read our 1,400+ потребителски ревюта

Защо да поръчвате от MedsBase

Every MedsBase order ships from a WHO-GMP certified manufacturer in plain, fully discreet packaging — nothing on the outside identifies the contents or the pharmacy. Card payments run through a regulated crypto on-ramp; the statement descriptor on your bank record is the processor name (a regulated card-payment processor) — never “MedsBase” or anything pharmacy-related. Crypto payments via Plisio stay fully anonymous. Every parcel is covered by our Политика за повторна изпратка.

What Is Livial?

Livial is a branded generic of tibolone 2.5 mg, a selective tissue estrogenic activity regulator (STEAR). Tibolone is a synthetic steroid that is metabolised in different tissues to compounds with estrogen-like, progestin-like, or androgen-like effects — producing a favourable profile in some tissues and less activity in others. Manufactured by Organon.

Clinical profile: estrogenic in bone, brain, and vagina (symptom relief), progestogenic in endometrium (does not stimulate endometrial proliferation — no separate progestin needed), androgenic in breast and liver (may help libido; may also affect lipid profile).

Клинични приложения

Menopausal vasomotor symptoms (hot flushes, night sweats) — ~70–80% reduction in trials.
Genitourinary syndrome of menopause — vaginal dryness, dyspareunia.
Postmenopausal osteoporosis prevention — reduces vertebral fracture risk.
Women preferring single-agent HRT — no separate progestin tablet needed.
Some women report libido benefit from tibolone’s mild androgenic activity (unique among HRT options).

Start Criteria

At least 12 months past the last period (tibolone in perimenopausal women causes irregular bleeding).
Natural or surgical menopause (post-hysterectomy, post-bilateral oophorectomy).
Symptoms significant enough to warrant treatment.
No contraindications (see below).

Как се приема

Приемете one tablet (2.5 mg) once daily, at roughly the same time each day, with water. With or without food.
Effect on vasomotor symptoms typically begins within 4–8 weeks; peak response at 3 months.
Continuous daily dosing, every day — no cyclic breaks.
If starting within 12 months of last period, irregular bleeding is more likely; wait until at least 1 year post-menopause.
Review annually for ongoing need. Most guidelines recommend the lowest effective dose for the shortest effective duration.

Safety — LIFT and LIBERATE Trials

Two major trials shaped tibolone safety understanding:

LIFT trial (osteoporosis prevention in older women): showed increased stroke risk in women over 60 taking tibolone. Use is now not recommended in women over 60 for new initiation.
LIBERATE trial (breast cancer survivors): showed increased breast cancer recurrence when tibolone was used in women with prior breast cancer. Contraindicated in breast cancer survivors.
In women <60 without breast cancer history, tibolone has a reasonable safety profile with efficacy comparable to low-dose combined HRT.

Странични ефекти

Чести: vaginal discharge, breast tenderness (less than combined HRT), weight gain (mild), lower abdominal pain, breast enlargement.

По-рядко: androgenic effects — mild acne, increased facial hair, oily skin (from tibolone’s weak androgenic activity), mood changes.

Сериозни (рядко): stroke (particularly in women over 60), breast cancer recurrence (in prior breast cancer survivors), VTE (lower than oral combined HRT but not zero), unexpected uterine bleeding (investigate).

Who Should Not Take Livial

Women over 60 initiating new HRT (stroke risk) — use alternatives
History of breast cancer — contraindicated per LIBERATE
History of estrogen-dependent cancer or unexplained vaginal bleeding
Current or history of VTE, DVT, or PE
History of stroke or TIA
Активно заболяване на черния дроб
Known pregnancy (should not occur post-menopause)
Within 12 months of last menstrual period (irregular bleeding)
Известна хиперчувствителност

Tibolone vs Combined HRT — Decision Framework

Consideration	Tibolone	Combined HRT (estrogen+progestin)
Pills per day	1	1 or 2 (depending on regimen)
Bleeding profile	~90% bleed-free after 3 months	Withdrawal bleed (sequential) or bleed-free (continuous-combined)
Libido	Mild androgenic benefit reported	Neutral or slightly suppressive
Use in women over 60	Avoid initiation (stroke risk)	Unfavourable risk-benefit over 60
Breast cancer survivors	Противопоказано (LIBERATE)	Противопоказано
VTE risk	Low (lower than oral combined HRT)	Moderate (oral route, higher)

Съхранение

Store at room temperature (15–25 °C / 59–77 °F), away from moisture. Keep in original packaging.

Често задавани въпроси

Is tibolone HRT?

Yes, in effect — it is a form of hormone therapy for menopausal symptoms. It differs from classic HRT because one tablet delivers estrogen-like, progestin-like, and mild androgen-like effects, so no separate progestin is needed.

Can I start tibolone if I'm still having periods?

No. Tibolone causes irregular bleeding in perimenopausal women. Wait until 12 months after your last period.

Will I bleed on tibolone?

About 90% of women are bleed-free by 3 months on tibolone. Breakthrough bleeding in the first 3 months is common and usually settles. Persistent bleeding beyond 6 months needs investigation.

Is tibolone safer than combined HRT?

Mixed. Tibolone has lower VTE risk than oral combined HRT but slightly elevated stroke risk in women over 60 (LIFT trial) and contraindicated in breast cancer survivors (LIBERATE). In women under 60 without breast cancer history, it’s a reasonable option.

Can I switch from combined HRT to tibolone?

Yes, but typically after 12 months of stable HRT. Discuss with a clinician — switching involves a short overlap or washout depending on current regimen.

Does tibolone help with libido?

Some women report libido benefit from tibolone’s mild androgenic activity. This is a unique feature vs standard estrogen-based HRT.

Will tibolone cause weight gain?

Small weight changes (~1–2 kg) are reported. Tibolone is generally weight-neutral in controlled trials, though individual variation exists.

How long can I take tibolone?

Modern guideline: lowest effective dose for the shortest effective duration. Annual review. Long-term safety data are reassuring for women under 60 who don’t have contraindications.

Related Hormone & Women’s Health Products

⚕️ Медицинско предупреждение: Information is educational and does not replace medical advice. Hormone therapies carry specific risks (breast cancer, VTE, stroke, endometrial cancer if unopposed estrogen) — consult a clinician before starting, stopping, or changing any hormone medication. Individual risk–benefit depends on personal and family medical history.