Levolin Rotacaps

📦 Всяка поръчка е покрита от нашата Политика за повторна изпратка — ако вашата пратка не пристигне в рамките на 20 работни дни, ние я изпращаме отново.

Защо да поръчвате от MedsBase

Нашите генерични лекарства се доставят от производители, сертифицирани от WHO-GMP, и се изпращат по целия свят в дискретна, обикновена опаковка — без име на лекарството външно на пратката. Плащанията с карта се обработват чрез регулиран процесор (описанието на извлечението включва регулиран процесор за плащане с карта — никога “MedsBase” или име на лекарство). Приемат се също криптовалути и банков превод SEPA. Всяка поръчка е подкрепена от нашата политика за гарантирано преизпращане.

What Is Levolin Rotacaps?

Levolin Rotacaps is a dry-powder rotacaps произведени от Cipla at WHO-GMP certified facilities. Each rotacaps delivers 100 mcg per rotacap of levosalbutamol. levosalbutamol is on the WHO List of Essential Medicines and is the world’s most-used reliever medication for asthma and reversible airflow obstruction.

Levosalbutamol is the pharmacologically active R-(−)-enantiomer of salbutamol. Standard salbutamol is a 50:50 racemic mixture of R and S isomers; the S-isomer contributes nothing to bronchodilation but may worsen airway hyperreactivity in some patients. By using only the R-isomer, levosalbutamol delivers the same therapeutic effect at half the milligram dose, with potentially less tremor and tachycardia in sensitive patients (especially children and those with cardiovascular comorbidities).

How Does Levolin Rotacaps Work?

levosalbutamol selectively activates beta-2 adrenergic receptors on the smooth muscle that rings the bronchial airways. Receptor activation raises intracellular cyclic AMP, smooth muscle relaxes, and the airway lumen widens — this is bronchodilation. Bronchodilation begins within 1–5 minutes, peaks at 30–90 minutes, and lasts 4–6 часа. levosalbutamol also modestly inhibits mast-cell mediator release, reduces plasma exudation from airway capillaries, and improves mucociliary clearance.

Selectivity is dose-dependent: at therapeutic doses, β2 effects predominate; at higher systemic doses (oral tablets, repeated nebulisation), spillover onto β1 receptors causes tachycardia and palpitations, and onto β2 receptors elsewhere causes tremor and hypokalaemia.

Употреба и показания

• Acute asthma exacerbations — first-line reliever (rescue) inhaler/nebulisation
• Chronic obstructive pulmonary disease (COPD) — symptomatic relief of acute breathlessness and exercise dyspnoea
• Exercise-induced bronchoconstriction — inhaled 15–30 minutes before exercise
• Bronchospasm with allergen, cold air, or viral exposure
• Anaphylaxis with bronchospasm — adjunct to adrenaline
• Hyperkalaemia (off-label) — nebulised salbutamol drives K⁺ intracellularly

Важно: Levolin Rotacaps is a reliever, not a controller. It does not reduce underlying airway inflammation. Patients using more than the equivalent of one SABA canister per month, or needing a SABA more than three days per week outside of exercise pre-dosing, have poorly-controlled asthma and require step-up to inhaled corticosteroid (ICS) or ICS-LABA combination therapy.

Levolin Rotacaps Dosage

How to Use Levolin Rotacaps Properly

• Insert one rotacap into a Rotahaler with the coloured end facing down.
• Twist the base sharply — listen for the click that pierces the cap.
• Breathe out gently away from the device.
• Seal lips around the mouthpiece.
• Inhale forcefully and deeply in one fast breath; you should hear the rotacap whir.
• Hold breath 10 seconds, then breathe out slowly through the nose.
• Check the rotacap is empty; if powder remains, repeat the inhalation.

Side Effects of Levolin Rotacaps

Common (dose-related, settle within 30–60 minutes):

• Fine tremor, especially of the hands
• Palpitations or increased heart rate (typically 10–20 bpm rise)
• Главоболие
• Dry mouth, throat irritation (more common with DPI/MDI)
• Muscle cramps
• Hyperactivity or agitation in young children

По-рядко:

• Hypokalaemia — especially with high repeat doses, worsened by theophylline, steroids or loop diuretics
• Mild hyperglycaemia
• Insomnia if dosed late evening
• Possible paradoxical worsening with the R-isomer is rare

Serious (stop and seek emergency help):

• Severe allergic reaction / angio-oedema / anaphylaxis
• Paradoxical bronchospasm — worsening wheeze immediately after dose
• Cardiac arrhythmias (atrial fibrillation, supraventricular tachycardia)
• Severe hypokalaemia with arrhythmia or muscle weakness

Предупреждения и предпазни мерки

• Frequent {$brand} use = poor asthma control. Needing a reliever more than 3 days per week (excluding exercise pre-dosing) means the underlying disease is not managed. Step up ICS-based controller therapy.
• Carry your reliever with you — many fatal asthma attacks happen when the inhaler is at home or expired.
• Cardiovascular disease: use cautiously in severe coronary artery disease, arrhythmias, hyperthyroidism, or severe heart failure.
• Diabetes: monitor glucose with repeat high doses.
• Бременност и кърмене: levosalbutamol is used at the lowest effective dose. Uncontrolled asthma is more dangerous to mother and fetus than the drug itself.
• Severe attack red flags (call emergency services): no relief 10 min after a full dose, peak flow <50% of personal best, difficulty speaking in full sentences, blue lips or drowsiness.

Противопоказания

• Known hypersensitivity to levosalbutamol or any formulation excipient
• Tachyarrhythmias (uncontrolled) — relative contraindication
• Phaeochromocytoma — relative contraindication
• Hypertrophic obstructive cardiomyopathy — caution

Лекарствени взаимодействия

Съхранение

• Store below 25°C in a dry place. Keep desiccant in the bottle.
• Do not store in the bathroom — humidity makes the powder clump and reduces dose delivery.
• Once the strip/blister is opened, use within the period stated on the leaflet (typically 2–3 months).
• Keep out of reach of children.

Свързани алтернативи в MedsBase

• Asthalin Respules — salbutamol nebuliser solution
• Budecort Inhaler — budesonide ICS preventer
• Foracort Inhaler — budesonide + formoterol ICS-LABA
• Seretide Accuhaler — fluticasone + salmeterol ICS-LABA
• Duolin Inhaler — salbutamol + ipratropium combo reliever

Често задавани въпроси

What is the difference between Levolin Inhaler and Levolin Rotacaps?

Both contain levosalbutamol. The Inhaler is a pressurised aerosol (50 mcg/actuation, propellant-driven, slow-deep inhalation). The Rotacaps are a dry-powder formulation (100 mcg/cap) requiring a Rotahaler device and a fast, forceful inhalation.

How forcefully do I need to breathe in?

Strong and fast — peak inspiratory flow ≥30 L/min (ideally 60). Children under 6 and patients in acute severe attacks may not generate this — use an MDI + spacer or nebuliser respule instead.

Why didn’t I taste anything?

Pure levosalbutamol powder is nearly tasteless — normal. Verify the rotacap is empty after inhalation.

Can I use Levolin Rotacaps with a spacer?

No — DPIs cannot be used with spacers. Spacers are only for pressurised metered-dose inhalers.

How many rotacaps a day is safe?

Up to 4 rotacaps (400 mcg) typically. Going above this regularly = poorly-controlled asthma → step up controller.

What if a rotacap gets damp?

Moisture clumps the powder and reduces effective dose. Keep in original blister with desiccant; never store in the bathroom.

Are Levolin Rotacaps safe for children?

From age 6 with confirmed inspiratory flow. Below 6, use MDI + spacer or nebuliser.

How does levosalbutamol compare to salbutamol DPI?

Same mechanism. Levosalbutamol uses half the milligram dose for similar bronchodilation, with potentially less tremor and tachycardia in sensitive patients.

How should I clean the Rotahaler?

Wipe the mouthpiece with a dry tissue weekly. Do not wash with water — moisture damages the device and clumps any residual powder.

More options in Asthma/COPD Treatment

Класирани според скорошния обем на поръчки в MedsBase — какво избират други клиенти в тази категория.

Asthalin

US$2.00 – US$8.00Ártartomány: US$2.00 és US$8.00 között

Aerocort Inhaler

US$6.00 – US$14.00Ártartomány: US$6.00 és US$14.00 között

Asthalin Respules

US$10.90 – US$27.50Ártartomány: US$10.90 és US$27.50 között