Maxiliv Injection
Maxiliv Injection (Glutathione 600 mg per IV vial) — antioxidant tripeptide for chemotherapy-induced peripheral neuropathy and oxidative liver stress. Hospital-administered. Not for cosmetic skin-whitening (FDA-warned). WHO-GMP certified manufacturer.
✓ Медицински преглед от Morgan Ellis — Фармацевтичен изследовател · 8 години опит · Последен преглед: май 2026 г.
⚡ Quick Answer — What is Maxiliv Injection?
Maxiliv Injection is reduced glutathione (GSH) 600 mg per vial for IV use — a tripeptide antioxidant (glutamate-cysteine-glycine) used clinically for oxidative liver stress, cisplatin- or oxaliplatin-induced peripheral neuropathy, and adjunct therapy in chemotherapy. It is administered intravenously by a healthcare professional. Glutathione is the body’s principal intracellular antioxidant, neutralising reactive oxygen species and conjugating reactive electrophiles for renal/biliary excretion.
📦 Всяка поръчка е покрита от нашата Политика за повторна изпратка — ако вашата пратка не пристигне в рамките на 20 работни дни, ние я изпращаме отново.
Защо да поръчвате от MedsBase
Нашите генерични лекарства се доставят от производители, сертифицирани от WHO-GMP, и се изпращат по целия свят в дискретна, обикновена опаковка — без име на лекарството външно на пратката. Плащанията с карта се обработват чрез регулиран процесор (описанието на извлечението включва регулиран процесор за плащане с карта — никога “MedsBase” или име на лекарство). Приемат се също криптовалути и банков превод SEPA. Всяка поръчка е подкрепена от нашата политика за гарантирано преизпращане.
Защо да поръчвате от MedsBase
Maxiliv Injection is supplied from a WHO-GMP certified manufacturer. Every order ships discreetly worldwide and is covered by our Политика за повторна изпратка — if it does not arrive within 20 business days, we reship at no cost. IV glutathione is used as supportive therapy in oncology and hepatology — not as a cosmetic intervention. Clinical doses, frequencies, and administration protocols are determined by the treating physician.
Mechanism
Glutathione is a thiol tripeptide that exists in reduced (GSH) and oxidised (GSSG) forms; the reduced form donates electrons to neutralise hydrogen peroxide and lipid peroxides via glutathione peroxidase, and conjugates reactive electrophiles via glutathione-S-transferase. Cellular glutathione is depleted by oxidative stress, paracetamol overdose, alcohol, ageing, and several disease states. IV glutathione transiently raises circulating levels; cellular uptake of intact GSH is limited, but the molecule is hydrolysed and the constituent amino acids (especially cysteine, the rate-limiting precursor) support intracellular re-synthesis.
Clinical indications
- Cisplatin- and oxaliplatin-induced peripheral neuropathy (Schmitt 2009 trial — preserved sensory nerve function on serial nerve-conduction studies)
- Oxidative liver stress in chronic hepatitis, fatty liver, post-anaesthetic, post-chemotherapy
- Acute paracetamol toxicity (N-acetylcysteine is the standard antidote that replenishes intracellular GSH; IV GSH is supplementary)
- Some Parkinson’s disease research protocols (off-label, low evidence)
- Idiopathic pulmonary fibrosis adjunct (low evidence)
Doses (clinician-determined)
Cisplatin-induced neuropathy: 1.5–2.4 g IV before each chemotherapy cycle. Hepatic support: 600 mg–1.2 g once daily or every other day. Always slow IV push or short infusion in compatible diluent (typically 5 percent dextrose or normal saline; check compatibility per local protocol).
Side effects
- Injection-site reactions, mild venous irritation
- Sulphurous taste / smell during infusion
- Hypersensitivity (rare; thiol allergy, asthma triggers)
- Stevens-Johnson syndrome / TEN (rare but reported, particularly with frequent unsupervised cosmetic dosing)
- Thyroid dysfunction with chronic high-dose use (FDA cosmetic-use warning)
- Renal impairment (rare)
Cautions
- Severe asthma (sulphite/thiol exacerbation risk)
- Active malignancy — specialist oncology decision (concern that antioxidant therapy could blunt chemo cytotoxicity offset by neuroprotection benefit)
- Pregnancy and breastfeeding — insufficient data, avoid unless clinical benefit is clear
- Renal impairment — reduce dose
Често задавани въпроси
Can I have IV glutathione for skin-whitening?
No — this is not a recognised medical indication. The FDA has issued specific warnings against unsupervised IV glutathione for cosmetic use due to serious adverse-event reports.
Does it really protect against chemo-induced neuropathy?
Schmitt 2009 (Italian Multicentre Cooperative Group) showed reduced sensory neuropathy on cisplatin in colorectal cancer patients pre-treated with IV glutathione. Several subsequent trials have shown variable effects. It remains an option in oncology supportive care but is not universally adopted.
How is it administered?
By a healthcare professional, intravenously, after reconstitution with a compatible diluent. Self-administration is unsafe and not endorsed.
Are there oral alternatives?
Liposomal oral glutathione has modest absorption. N-acetylcysteine (NAC) 600–1200 mg/day is a more bioavailable cysteine precursor and is the standard oral approach to raising intracellular glutathione.
Is it safe in pregnancy?
Insufficient data — avoid unless the clinical situation strongly justifies it. NAC has a longer pregnancy safety record.
Can I take it with chemotherapy?
Only under oncology supervision. The interaction between antioxidant supplementation and chemotherapy efficacy is debated; clinical decisions need to be made within the multidisciplinary team.
Why does it smell of sulphur?
Glutathione contains a sulfhydryl (-SH) group. The smell during infusion is harmless and dissipates within minutes.
How often should I have it?
Determined by the treating clinician. Frequent dosing (more than once weekly) is not supported by clinical evidence and increases risk of adverse reactions.
Storage
Below 25°C, protect from light. Discard reconstituted solution if not used within the local protocol’s stability window (typically 2–4 hours).
What if I miss a dose?
Discuss with the treating clinician. Do not self-administer or arrange unsupervised infusions.
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| Сила | 600 mg |
|---|---|
| Количество | 1 Vial/s, 2 Vial/s, 3 Vials/s, 6 Vial/s |
Maxiliv Injection
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Maxiliv Injection
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