Oxitan Injection
Oxitan Injection (Oxaliplatin) — Celon Labs third-generation platinum for colorectal cancer (FOLFOX, CAPEOX). Cumulative peripheral neuropathy is dose-limiting.
✓ Ιατρικά ελεγμένο από Morgan Ellis — Ερευνητής Φαρμακευτικής · 8 χρόνια εμπειρία · Τελευταία αναθεώρηση: Μάιος 2026
Γρήγορη απάντηση
Oxitan Injection — Oxaliplatin (Celon Laboratories). Platinum-based DNA cross-linking chemotherapy. Third-generation platinum for colorectal cancer (FOLFOX, CAPEOX). Less nephrotoxic than cisplatin; cumulative peripheral neuropathy is dose-limiting. Hospital-administered IV. Strict pre-medication, hydration, and antiemetic protocols.
Αυτό που λαμβάνετε με την MedsBase:
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- Συσκευασία σε απλό φάκελο χωρίς ενδείξεις
- Παγκόσμια αποστολή
- Αξιολογήθηκε από 1,400+ πελάτες (διαβάστε κριτικές)
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Γιατί να παραγγείλετε από τη MedsBase
Oxitan Injection ships from a WHO-GMP certified manufacturer in plain packaging, billed through a regulated payment processor (the statement descriptor reads a regulated card-payment processor — never MedsBase or any medication name). Every order carries our 20-business-day Reshipment Assurance.
⚠️ Specialist-supervised cancer therapy — this medication is started, monitored, and stopped by an oncologist or haematologist. Dosing depends on tumour type, stage, body surface area, organ function, and concomitant therapy. Self-treatment is not appropriate; the information below is educational and supports informed conversations with your specialist.
All platinum agents are hospital-administered intravenous chemotherapy under specialist supervision. Self-administration is not appropriate. Pre-medication, hydration, antiemetic regimens, and monitoring are part of the protocol.
Cisplatin: nephrotoxicity (mandatory hyperhydration), severe nausea/vomiting, ototoxicity (especially in children — pre/post audiometry), peripheral neuropathy, electrolyte wasting (Mg, K). Oxaliplatin: cumulative peripheral neuropathy (cold-triggered acute neuropathy is distinctive), less nephrotoxic, less emetogenic. Carboplatin: dose-limiting myelosuppression, AUC-based dosing (Calvert formula).
Συχνές Ερωτήσεις
When is platinum chemotherapy used?
Cisplatin: testicular, ovarian, lung, bladder, head and neck, cervical cancers. Oxaliplatin: colorectal cancer (FOLFOX, CAPEOX). Carboplatin: ovarian, lung, breast, head and neck — typically when cisplatin toxicity profile is unacceptable.
How is it given?
IV infusion in a chemotherapy day-unit. Pre-medication includes antiemetics (5-HT3 antagonist + dexamethasone + NK1 antagonist), IV fluids (cisplatin requires aggressive hydration). Each cycle is 2-4 weeks depending on regimen.
Side effects to expect?
Nausea/vomiting (managed with antiemetics), fatigue, neutropenia, thrombocytopenia, neuropathy (oxaliplatin especially), tinnitus/hearing loss (cisplatin), renal dysfunction (cisplatin).
Pre-medication?
Antiemetics: ondansetron + dexamethasone + (for highly emetogenic regimens) aprepitant. Hydration: 1-3 L of saline before/after cisplatin.
Renal monitoring?
Cisplatin: baseline + before each cycle + weekly during therapy. Stop or switch if creatinine rises >25% from baseline. Magnesium and potassium replacement common.
Hearing test?
Audiometry baseline and as clinically indicated for cisplatin (especially in paediatric, repeated cycles, or pre-existing hearing loss).
Εγκυμοσύνη;
Strongly contraindicated — teratogenic and abortifacient. Effective contraception during and for ≥6 months after for both partners.
Αλληλεπιδράσεις φαρμάκων;
Aminoglycosides + cisplatin: massive nephrotoxicity. NSAIDs + cisplatin: nephrotoxicity. Phenytoin levels may drop with platinum chemo. Always disclose all medications.
Cumulative dose limits?
Cisplatin: stop or switch at cumulative neurotoxicity, ototoxicity, or persistent renal impairment. Oxaliplatin: total dose 850 mg/m² is associated with cumulative neuropathy — protocols typically include planned breaks (FOLFOX 4-6, then re-introduction).
When is treatment stopped?
Tumour response/disease progression dictates duration. Specialist decision based on response evaluation criteria (RECIST), toxicity, and patient goals.
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| Ισχύς | 50mg/25ml, 100mg/50ml |
|---|---|
| Ποσότητα | 1 Injection/s, 3 Injection/s, 6 Injection/s |
| Φαρμακευτική Μορφή | Injection/s |
| Κατασκευαστής | Fresenius Kabi |
| Θεραπεία | Cancer of colon and rectum |
| Γενόσημη μάρκα | Oxaliplatin |
Oxitan Injection
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Oxitan Injection
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